Enwemeka_2004
Supportive Therapie · Version 2.1
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Referenz (Autor, Jahr, Journal) |
Studientyp Mono- vs. Multizentrisch, Verblindung, Randomisierung, Arme, Fallzahl n, Land, Zeitraum
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Patienten-merkmale Indikation, Alter, Geschlecht (m/w) |
Intervention Fallzahl n, Beschreibung der präventiven bzw. therapeutischen Maßnahme |
Kontrolle Fallzahl n, Beschreibung der präventiven Maßnahme bzw. therapeutischen Maßnahme |
Zielgrößen Primärer Endpunkt Sekundäre(r) Endpunkt(e) |
Primärer Endpunkt Angaben für Intervention vs. Kontrolle Sekundäre(r) Endpunkt(e) Angaben für Intervention vs. Kontrolle |
Finanzierung |
Evidenzstufe Bei Abwertung: Angabe von Gründen Bewertung des Autors |
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Enwemeka
2004
Photomedicine and Laser Surgery |
Meta-Analysis Study
34 tissue repair studies
9 pain control papers
USA
published within the last 30 years
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condition treated (e.g., bed sores, venous ulcers, diabetic ulcers, surgical wounds) |
Low-Power Laser with ≤ 500 mW average power |
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Cohen’s d
Tissue Repair
Pain Control |
pain relief: effect size: +1.11 (SD = 1.02; median = +0.79; 95% CI = +0.44 to +1.78).
tissue repair: effect size: +1.81; (SD = 2.26; median = 0.88; 95% CI = 1.16 to 2.46)
collagen formation (d = +2.78) rate of healing (d = +1.57) tensile strength (d = +2.13) time needed for wound closure (d = +0.76) tensile stress (d = +2.65) number and rate of degranulation of mast cells (d = +1.87) flap survival (d = +1.95)
various wavelengths of laser light on tissue repair: 632.8 nm (d = +2.44) 780 nm (d = 0.60).
fail-safe number tissue repair: 370 pain control: 41 |
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2a only papers published in the English literature
"These findings mandate the conclusion that laser phototherapy is a highly effective therapeutic armamentarium for tissue repair and pain relief." |