Kakoei 2013
Supportive Therapie · Version 2.1
|
Referenz (Autor, Jahr, Journal) |
Studientyp Mono- vs. Multizentrisch, Verblindung, Randomisierung, Arme, Fallzahl n, Land, Zeitraum |
Patienten-merkmale Indikation, Alter, Geschlecht (m/w) |
Intervention Fallzahl n, Beschreibung der präventiven bzw. therapeutischen Maßnahme Kontrolle Fallzahl n, Beschreibung der präventiven Maßnahme bzw. therapeutischen Maßnahme |
Zielgrößen Primärer Endpunkt Sekundäre(r) Endpunkt(e) |
Primärer Endpunkt Angaben für Intervention vs. Kontrolle Sekundäre(r) Endpunkt(e) Angaben für Intervention vs. Kontrolle |
Finanzierung |
Evidenzstufe Bei Abwertung: Angabe von Gründen Bewertung des Autors |
|
Kakoei
2013
International Journal of Radiation Research
|
randomized controlled trial
1 centre
n = 40
Iran |
head and neck cancer with radiotherapy
male: 23 (57.5%)
average age: control group: 49.1±15.4 y Experimental group: 42.9±14.9 y
Average received radiation dose: 5387 cGy
|
experimental group (n=20)
sucking ice cubes before and afer each radiotherapy session for five minutes
control group (n=20) |
effect of ice cubes on oral mucosits following head and neck radiotherapy |
Pain severity experimental 1st day 2.22±0.43 7th day 2.95±0.42 14th day 2.7±0.38 p = 0.155 control 1st day 0.55±0.28 7th day 2.00±0.51 14th day 2.85±0.58 p < 0.001
Physician‐judged mucosits grading experimental 1st day 0.55±0.15 7th day 1.10±0.12 14th day 0.95±0.13 p < 0.05 control 1st day 0.50±0.17 7th day 0.85±0.18 14th day 1.2±0.20 p < 0.001 |
This study was Financially supported by the Office of Vice Chancellor for Research of Kerman University of Medical Sciences, to which the authors extend their appreciation |
2b single centre
"Although no significant difference was observed in mucosits intensity between the experimental and control groups, patents using ice cubes during radiotherapy sessions felt more comfort in their oral cavity." |