Koszo_2019

Referenz

(Autor, Jahr, Journal)

Studientyp

Mono- vs. Multizentrisch, Verblindung, Randomisierung, Arme, Fallzahl n, Land, Zeitraum

Patienten-merkmale

Indikation, Alter, Geschlecht (m/w)

Intervention

Fallzahl n, Beschreibung der präventiven bzw. therapeutischen Maßnahme

Kontrolle

Fallzahl n, Beschreibung der präventiven Maßnahme bzw. therapeutischen Maßnahme

Zielgrößen

Primärer Endpunkt

Sekundäre(r) Endpunkt(e)

Primärer Endpunkt

Angaben für Intervention vs. Kontrolle

Sekundäre(r) Endpunkt(e)

Angaben für Intervention vs. Kontrolle

Finanzierung

Evidenzstufe

Bei Abwertung: Angabe von Gründen

Bewertung des Autors

Kószó

2019

Pathology & Oncology Research

prospective analysis

single centre

n = 55

Hungary

10/2016 – 10/2017

prostate cancer

definitive pelvic RT

median [range] age: 65.60 [53.33–83.49] years

median [range] value of body mass index: 26.96

[19.37–41.62] kg/m2

supine positions on a belly board

prone positions on a belly board

exposure of organs at risk (OARs) using intensity modulated RT (IMRT).

volumes of the prostate, PTV, colon and small bowel:  no significant differences

prone position: all rectal volumes, diameters, and rectum–prostate distance were significantly higher

irradiated colon and small bowel volume was lower in dose ranges of 20–40 Gy

exposure to all rectal segments was more favorable in 40–75 Gy dose ranges

No significant difference was found in the exposure of other OARs

Prone positioning on a belly board is an appropriate positioning method aiming rectum and bowel protection during pelvic IMRT of prostate cancer. The relative reduction in rectal exposure might be a consequence of the slight departure between the prostate and rectal wall

The authors declare that they have no conflict of

interest

3

relatively small number of patients
lack of delineating the penile bulb
short follow-up period - no information about late toxicities

"Prone positioning on a belly board is an appropriate positioning method aiming rectum and bowel protection during pelvic IMRT of prostate cancer. The relative reduction in rectal exposure might be a consequence of the slight departure between the prostate and rectal wall."