Leitlinienprogramm OnkologieSpeicheldrüsentumoren

8. Literaturverzeichnis – Speicheldrüsentumoren

Version 1.0 · Juli 2025 · AWMF 007-102OL
Leitlinienprogramm Onkologie · Deutsche Krebsgesellschaft · Deutsche Krebshilfe · AWMF

1. Fritz A,, Percy C,, Jack A,, Shanmugaratnam K,, Sobin L,, Parkin DM,, et.al. International Classification of Diseases for Oncology (ICD-O), 2000. 3rd edition ed.:

2. Seifert, G, Sobin, LH, The World Health Organization's Histological Classification of Salivary Gland Tumors. A commentary on the second edition., Cancer, 1992. 70 (2)(2): p. 379-85., https://pubmed.ncbi.nlm.nih.gov/1617588/

3. Ihrler, S, Guntinas-Lichius, O, Haas, C, Mollenhauer, M, [Updates on tumours of the salivary glands : 2017 WHO classification]., Pathologe, 2018. 39 (1)(1): p. 11-17., https://pubmed.ncbi.nlm.nih.gov/29372306/

4. Pinkston, J. A., Cole, P., Incidence rates of salivary gland tumors: results from a population-based study, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1999. 120(6): p. 834-40., http://www.ncbi.nlm.nih.gov/pubmed/10352436

5. Mortensen, K. S., Hjortlund, J., Bjorndal, K., Krogdal, A., Godballe, C., [Salivary gland tumors in the County of Funen, 1984-2003], Ugeskrift for laeger, 2008. 170(7): p. 545-8., http://www.ncbi.nlm.nih.gov/pubmed/18291086

6. PJ., Bradley, General epidemiology of salivary gland tumours, in Controversies in the management of salivary gland diseases, McGurk M.C., Renehan A. , Editor. 2013, Oxford University Press.

7. Bradley, P. J., McGurk, M., Incidence of salivary gland neoplasms in a defined UK population, Br J Oral Maxillofac Surg, 2013. 51(5): p. 399-403.

8. Moeller, K, Esser, D, Boeger, D, Buentzel, J, Hoffmann, K, Jecker, P, et.al. Parotidectomy and submandibulectomy for benign diseases in Thuringia, Germany: a population-based study on epidemiology and outcome., Eur Arch Otorhinolaryngol, 2013. 270 (3)(3): p. 1149-55., https://pubmed.ncbi.nlm.nih.gov/23073736/

9. Guntinas-Lichius, O., Wendt, T. G., Kornetzky, N., Buentzel, J., Esser, D., Boger, D., et.al. Trends in epidemiology and treatment and outcome for head and neck cancer: a population-based long-term analysis from 1996 to 2011 of the Thuringian cancer registry, Oral oncology, 2014. 50(12): p. 1157-64., http://www.ncbi.nlm.nih.gov/pubmed/25459063

10. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) - Ständige Kommission Leitlinien, AWMF-Regelwerk „Leitlinien“, Auflage 2.1, 2023., https://www.awmf.org/regelwerk/

11. Atkins, D, Best, D, Briss, PA, Eccles, M, Falck-Ytter, Y, Flottorp, S, et.al. Grading quality of evidence and strength of recommendations., BMJ, 2004. 328 (7454)(7454): p. 1490., https://pubmed.ncbi.nlm.nih.gov/15205295/

12. Kraft, M., Lang, F., Mihaescu, A., Wolfensberger, M., Evaluation of clinician-operated sonography and fine-needle aspiration in the assessmentof salivary gland tumours, Clin Otolaryngol, 2008. 33(1): p. 18-24., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1749-4486.2007.01598.x?download=true

13. Haldrup, Mette, Yde, Simon, Bolvig, Lars, Stolle, Lars, Utility of ultrasound of the lymph nodes in patients with high-risk cutaneous squamous cell carcinoma, 2018/12/01. 41: p. 1 - 6., https://link.springer.com/article/10.1007/s00238-018-1432-1

14. Haidar, YM, Moshtaghi, O, Mahmoodi, A, Helmy, M, Goddard, JA, Armstrong, WB, The Utility of In-Office Ultrasound in the Diagnosis of Parotid Lesions., Otolaryngol Head Neck Surg, 2017. 156 (3)(3): p. 511-517., https://pubmed.ncbi.nlm.nih.gov/28118551/

15. Berner, F, Koch, M, Müller, SK, Schapher, M, Grundtner, P, Iro, H, et.al. Investigation of Sonographic Criteria for Reliable Identification of T1-T2 Low-Grade Malignant Tumors of the Parotid Gland., Ultrasound Med Biol, 2021. 47 (3)(3): p. 471-477., https://pubmed.ncbi.nlm.nih.gov/33309444/

16. Li, C., Zhang, C., Li, N., Li, J., Compression Real-time Elastography for Evaluation of Salivary Gland Lesions: A Meta-analysis, J Ultrasound Med, 2016. 35(5): p. 999-1007., https://pubmed.ncbi.nlm.nih.gov/27072157/

17. Zhang, Y. F., Li, H., Wang, X. M., Cai, Y. F., Sonoelastography for differential diagnosis between malignant and benign parotidlesions: a meta-analysis, Eur Radiol, 2019. 29(2): p. 725-735., https://pubmed.ncbi.nlm.nih.gov/29992386/

18. Mansour, N, Bas, M, Stock, KF, Strassen, U, Hofauer, B, Knopf, A, Multimodal Ultrasonographic Pathway of Parotid Gland Lesions., Ultraschall Med, 2017. 38 (2)(2): p. 166-173., https://pubmed.ncbi.nlm.nih.gov/26274381/

19. Liang, Y. Y., Xu, F., Guo, Y., Wang, J., accuracy of magnetic resonance imaging techniques for parotid tumors, a systematicreview and meta-analysis, Clin Imaging, 2018. 52: p. 36-43., https://pubmed.ncbi.nlm.nih.gov/29908348/

20. Celebi, I., Mahmutoglu, A. S., Ucgul, A., Ulusay, S. M., Basak, T., Basak, M., Quantitative diffusion-weighted magnetic resonance imaging in the evaluation of parotidgland masses: A study with histopathological correlation, Clinical Imaging, 2013. 37(2): p. 232-238., https://www.sciencedirect.com/science/article/abs/pii/S0899707112001647?via%3Dihub

21. Milad, P., Elbegiermy, M., Shokry, T., Mahmoud, H., Kamal, I., Taha, M. S., et.al. The added value of pretreatment DW MRI in characterization of salivary glands pathologies, Am J Otolaryngol, 2017. 38(1): p. 13-20., https://pubmed.ncbi.nlm.nih.gov/27806890/

22. Bertagna, F., Nicolai, P., Maroldi, R., Mattavelli, D., Bertoli, M., Giubbini, R., et.al. Diagnostic role of (18)F-FDG-PET or PET/CT in salivary gland tumors: A systematicreview, Rev Esp Med Nucl Imagen Mol, 2015. 34(5): p. 295-302., https://pubmed.ncbi.nlm.nih.gov/26488055/

23. Barbara, R. R., Pawaroo, D., Beadsmoore, C., Hujairi, N., Newman, D., Parotid incidentalomas on positron emission tomography: what is their clinical significance?, Nucl Med Commun, 2019. 40(3): p. 264-269., https://pubmed.ncbi.nlm.nih.gov/30614921/

24. Kong, X., Li, H., Han, Z., The diagnostic role of ultrasonography, computed tomography, magnetic resonance imaging,positron emission tomography/computed tomography, and real-time elastographyin the differentiation of benign and malignant salivary gland tumors:a meta-analysis, Oral Surg Oral Med Oral Pathol Oral Radiol, 2019. 128(4): p. 431-443.e1., https://pubmed.ncbi.nlm.nih.gov/31327623/

25. Liu, C. C., Jethwa, A. R., Khariwala, S. S., Johnson, J., Shin, J. J., Sensitivity, Specificity, and Posttest Probability of Parotid Fine-Needle Aspiration:A Systematic Review and Meta-analysis, Otolaryngol Head Neck Surg, 2016. 154(1): p. 9-23., https://journals.sagepub.com/doi/pdf/10.1177/0194599815607841

26. Colella, G., Cannavale, R., Flamminio, F., Foschini, M. P., Fine-needle aspiration cytology of salivary gland lesions: a systematic review, J Oral Maxillofac Surg, 2010. 68(9): p. 2146-53., https://pubmed.ncbi.nlm.nih.gov/20580145/

27. Farahani, S. J., Baloch, Z., Retrospective assessment of the effectiveness of the Milan system for reporting salivarygland cytology: A systematic review and meta-analysis of published literature, Diagn Cytopathol, 2019. 47(2): p. 67-87., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dc.24097?download=true

28. Schmidt, RL, Hall, BJ, Layfield, LJ, A systematic review and meta-analysis of the diagnostic accuracy of ultrasound-guided core needle biopsy for salivary gland lesions., Am J Clin Pathol, 2011. 136 (4)(4): p. 516-26., https://pubmed.ncbi.nlm.nih.gov/21917673/

29. Novoa, E., Gurtler, N., Arnoux, A., Kraft, M., Role of ultrasound-guided core-needle biopsy in the assessment of head and neck lesions:a meta-analysis and systematic review of the literature, Head Neck, 2012. 34(10): p. 1497-503., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hed.21821?download=true

30. Schmidt, RL, Hall, BJ, Wilson, AR, Layfield, LJ, A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions., Am J Clin Pathol, 2011. 136 (1)(1): p. 45-59., https://pubmed.ncbi.nlm.nih.gov/21685031/

31. Witt, B. L., Schmidt, R. L., Ultrasound-guided core needle biopsy of salivary gland lesions: a systematic review and meta-analysis, Laryngoscope, 2014. 124(3): p. 695-700., https://pubmed.ncbi.nlm.nih.gov/23929672/

32. Ihrler, Stephan, Agaimy, Abbas, Guntinas-Lichius, Orlando, Haas, Christian J, Mollenhauer, Martin, Sandison, Ann, et.al. Why is the histomorphological diagnosis of tumours of minor salivary glands much more difficult?, Histopathology, 2021. 79(5): p. 779-790., https://onlinelibrary.wiley.com/doi/abs/10.1111/his.14421

33. Foresta, E., Torroni, A., Di Nardo, F., de Waure, C., Poscia, A., Gasparini, G., et.al. Pleomorphic adenoma and benign parotid tumors: extracapsular dissection vs superficialparotidectomy--review of literature and meta-analysis, Oral Surg Oral Med Oral Pathol Oral Radiol, 2014. 117(6): p. 663-76., https://pubmed.ncbi.nlm.nih.gov/24767698/

34. Albergotti, W. G., Nguyen, S. A., Zenk, J., Gillespie, M. B., Extracapsular dissection for benign parotid tumors: a meta-analysis, Laryngoscope, 2012. 122(9): p. 1954-60., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/lary.23396?download=true

35. Lin, Y. Q., Wang, Y., Ou, Y. M., Dong, S. Y., Wang, Y. D., Extracapsular dissection versus partial superficial parotidectomy for the treatmentof benign parotid tumours, International Journal of Oral and Maxillofacial Surgery, 2019. 48(7): p. 895-901., https://www.sciencedirect.com/science/article/abs/pii/S090150271930089X?via%3Dihub

36. Quer, M, Vander Poorten, V, Takes, RP, Silver, CE, Boedeker, CC, de Bree, R, et.al. Surgical options in benign parotid tumors: a proposal for classification., Eur Arch Otorhinolaryngol, 2017. 274 (11)(11): p. 3825-3836., https://pubmed.ncbi.nlm.nih.gov/28639060/

37. Mashrah, MA, Al-Sharani, HM, Al-Aroomi, MA, Abdelrehem, A, Aldhohrah, T, Wang, L, Surgical interventions for management of benign parotid tumors: Systematic review and network meta-analysis., Head Neck, 2021. 43 (11)(11): p. 3631-3645., https://pubmed.ncbi.nlm.nih.gov/34288212/

38. Mantsopoulos, K, Koch, M, Klintworth, N, Zenk, J, Iro, H, Evolution and changing trends in surgery for benign parotid tumors., Laryngoscope, 2015. 125 (1)(1): p. 122-7., https://pubmed.ncbi.nlm.nih.gov/25043324/

39. Psychogios, Georgios, Bohr, Christopher, Constantinidis, Jannis, Canis, Martin, Vander Poorten, Vincent, Plzak, Jan, et.al. Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors, 2021. 278(1): p. 15 - 29., https://doi.org/10.1007/s00405-020-06250-x

40. Bär, B, Mantsopoulos, K, Iro, H, Paradigm shift in surgery for benign parotid tumors: 19 years of experience with almost 3000 cases., Laryngoscope, 2020. 130 (8)(8): p. 1941-1946., https://pubmed.ncbi.nlm.nih.gov/31804719/

41. Quer, M, Guntinas-Lichius, O, Marchal, F, Vander Poorten, V, Chevalier, D, León, X, et.al. Classification of parotidectomies: a proposal of the European Salivary Gland Society., Eur Arch Otorhinolaryngol, 2016. 273 (10)(10): p. 3307-12., https://pubmed.ncbi.nlm.nih.gov/26861548/

42. Stathopoulos, P., Igoumenakis, D., Smith, W. P., Partial Superficial, Superficial, and Total Parotidectomy in the Management of BenignParotid Gland Tumors: A 10-Year Prospective Study of 205 Patients, Journal of Oral and Maxillofacial Surgery, 2018. 76(2): p. 455-459., https://www.sciencedirect.com/science/article/abs/pii/S0278239117307176?via%3Dihub

43. Sood, AJ, Houlton, JJ, Nguyen, SA, Gillespie, MB, Facial nerve monitoring during parotidectomy: a systematic review and meta-analysis., Otolaryngol Head Neck Surg, 2015. 152 (4)(4): p. 631-7., https://pubmed.ncbi.nlm.nih.gov/25628369/

44. Chiesa-Estomba, CM, Larruscain-Sarasola, E, Lechien, JR, Mouawad, F, Calvo-Henriquez, C, Diom, ES, et.al. Facial nerve monitoring during parotid gland surgery: a systematic review and meta-analysis., Eur Arch Otorhinolaryngol, 2021. 278 (4)(4): p. 933-943., https://pubmed.ncbi.nlm.nih.gov/32654023/

45. Schmidt, RL, Hunt, JP, Hall, BJ, Wilson, AR, Layfield, LJ, A systematic review and meta-analysis of the diagnostic accuracy of frozen section for parotid gland lesions., Am J Clin Pathol, 2011. 136 (5)(5): p. 729-38., https://pubmed.ncbi.nlm.nih.gov/22031311/

46. Tam, S, Sandulache, VC, Metwalli, KA, Rock, CD, Eraj, SA, Sheu, T, et.al. Incompletely treated malignancies of the major salivary gland: Toward evidence-based care., Head Neck, 2018. 40 (8)(8): p. 1630-1638., https://pubmed.ncbi.nlm.nih.gov/29734482/

47. Guzzo, M., Locati, L. D., Prott, F. J., Gatta, G., McGurk, M., Licitra, L., Major and minor salivary gland tumors, Crit Rev Oncol Hematol, 2010. 74(2): p. 134-48., https://pubmed.ncbi.nlm.nih.gov/19939701/

48. Wittekindt, C, Streubel, K, Arnold, G, Stennert, E, Guntinas-Lichius, O, Recurrent pleomorphic adenoma of the parotid gland: analysis of 108 consecutive patients., Head Neck, 2007. 29 (9)(9): p. 822-8., https://pubmed.ncbi.nlm.nih.gov/17563905/

49. Redaelli de Zinis, LO, Piccioni, M, Antonelli, AR, Nicolai, P, Management and prognostic factors of recurrent pleomorphic adenoma of the parotid gland: personal experience and review of the literature., Eur Arch Otorhinolaryngol, 2008. 265 (4)(4): p. 447-52., https://pubmed.ncbi.nlm.nih.gov/17960409/

50. Leonetti, JP, Marzo, SJ, Petruzzelli, GJ, Herr, B, Recurrent pleomorphic adenoma of the parotid gland., Otolaryngol Head Neck Surg, 2005. 133 (3)(3): p. 319-22., https://pubmed.ncbi.nlm.nih.gov/16143173/

51. S3-Leitlinie Psychoonkologische Diagnostik, Beratung und Behandlung von erwachsenen Krebspatienten, AWMF-Registernummer 032/051OL, 2023.

52. Papadogeorgakis, N, Goutzanis, L, Petsinis, V, Alexandridis, C, Management of malignant parotid tumors., Oral Maxillofac Surg, 2012. 16 (1)(1): p. 29-34., https://pubmed.ncbi.nlm.nih.gov/21207235/

53. Israel, Y, Rachmiel, A, Ziv, G, Nagler, R, Diagnostic and therapeutic modalities for 287 malignant and benign salivary tumors: A cohort study., J Craniomaxillofac Surg, 2017. 45 (4)(4): p. 585-588., https://pubmed.ncbi.nlm.nih.gov/28238560/

54. Geiger, JL, Ismaila, N, Beadle, B, Caudell, JJ, Chau, N, Deschler, D, et.al. Management of Salivary Gland Malignancy: ASCO Guideline., J Clin Oncol, 2021. 39 (17)(17): p. 1909-1941., https://pubmed.ncbi.nlm.nih.gov/33900808/

55. Sood, S, McGurk, M, Vaz, F, Management of Salivary Gland Tumours: United Kingdom National Multidisciplinary Guidelines., J Laryngol Otol, 2016. 130 (S2)(S2): p. S142-S149., https://pubmed.ncbi.nlm.nih.gov/27841127/

56. Guntinas-Lichius, O., Klussmann, J. P., Schroeder, U., Quante, G., Jungehuelsing, M., Stennert, E., Primary Parotid Malignoma Surgery in Patients with Normal Preoperative Facial NerveFunction: Outcome and Long-Term Postoperative Facial Nerve Function, Laryngoscope, 2004. 114(5): p. 949-956., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1097/00005537-200405000-00032?download=true

57. Lim, Y. C., Lee, S. Y., Kim, K., Lee, J. S., Koo, B. S., Shin, H. A., et.al. Conservative parotidectomy for the treatment of parotid cancers, Oral Oncol, 2005. 41(10): p. 1021-7., https://pubmed.ncbi.nlm.nih.gov/16129655/

58. Park, G. C., Roh, J. L., Cho, K. J., Jin, M. H., Jung, Y. G., Lee, H. W., et.al. Clinically Node-Negative Parotid Gland Cancers: Prognostic Factors of Survival andSurgical Extent, Oncology, 2020. 98(2): p. 102-110., https://www.karger.com/Article/Pdf/503580

59. Olsen, K. D., Moore, E. J., Deep lobe parotidectomy: clinical rationale in the management of primary and metastatic cancer, Eur Arch Otorhinolaryngol, 2014. 271(5): p. 1181-5., https://pubmed.ncbi.nlm.nih.gov/23832259/

60. Klussmann, J. P., Ponert, T., Mueller, R. P., Dienes, H. P., Guntinas-Lichius, O., Patterns of lymph node spread and its influence on outcome in resectable parotid cancer, Eur J Surg Oncol, 2008. 34(8): p. 932-7., https://pubmed.ncbi.nlm.nih.gov/18358679/

61. Guntinas-Lichius, O, Silver, CE, Thielker, J, Bernal-Sprekelsen, M, Bradford, CR, De Bree, R, et.al. Management of the facial nerve in parotid cancer: preservation or resection and reconstruction., Eur Arch Otorhinolaryngol, 2018. 275 (11)(11): p. 2615-2626., https://pubmed.ncbi.nlm.nih.gov/30267218/

62. Vander Poorten, V., Bradley, P. J., Takes, R. P., Rinaldo, A., Woolgar, J. A., Ferlito, A., Diagnosis and management of parotid carcinoma with a special focus on recent advances in molecular biology, Head Neck, 2012. 34(3): p. 429-40., https://pubmed.ncbi.nlm.nih.gov/21618326/

63. Iseli, T. A., Karnell, L. H., Preston, T. W., Graham, S. M., Funk, G. F., Buatti, J. M., et.al. Facial nerve sacrifice and radiotherapy in parotid adenoid cystic carcinoma, Laryngoscope, 2008. 118(10): p. 1781-1786., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1097/MLG.0b013e31817fae29?download=true

64. Lee, KC, Chuang, SK, Does Total Parotidectomy Improve Survival Over Partial Parotidectomy in Early-Stage Adenoid Cystic Carcinoma of the Parotid Gland?, J Oral Maxillofac Surg, 2022. 80 (9)(9): p. 1550-1556., https://pubmed.ncbi.nlm.nih.gov/35772513/

65. Casler, JD, Conley, JJ, Surgical management of adenoid cystic carcinoma in the parotid gland., Otolaryngol Head Neck Surg, 1992. 106 (4)(4): p. 332-8., https://pubmed.ncbi.nlm.nih.gov/1314372/

66. Terakedis, B. E., Hunt, J. P., Buchmann, L. O., Avizonis, V. N., Anker, C. J., Hitchcock, Y. J., The Prognostic Significance of Facial Nerve Involvement in Carcinomas of the ParotidGland, Am J Clin Oncol, 2017. 40(3): p. 323-328., https://www.ingentaconnect.com/content/wk/ajco/2017/00000040/00000003/art00019;jsessionid=51bgb4fgh7a57.x-ic-live-01

67. Terhaard, C., Lubsen, H., Tan, B., Merkx, T., van der Laan, B., Baatenburg-de Jong, R., et.al. Facial nerve function in carcinoma of the parotid gland, European Journal of Cancer, 2006. 42(16): p. 2744-2750., https://pubmed.ncbi.nlm.nih.gov/16950616/

68. Gomez, D. R., Katabi, N., Zhung, J., Wolden, S. L., Zelefsky, M. J., Kraus, D. H., et.al. Clinical and pathologic prognostic features in acinic cell carcinoma of the parotidgland, Cancer, 2009. 115(10): p. 2128-37., https://acsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.24259?download=true

69. Park, W., Park, J., Park, S. I., Kim, H., Bae, H., Cho, J., et.al. Clinical outcomes and management of facial nerve in patients with parotid gland cancerand pretreatment facial weakness, Oral Oncol, 2019. 89: p. 144-149., https://www.sciencedirect.com/science/article/abs/pii/S136883751930003X?via%3Dihub

70. Zhang, X., Zeng, X., Lan, X., Huang, J., Luo, K., Tian, K., et.al. Reoperation following the use of non-standardized procedures for malignant parotidtumors, Oncology Letters, 2017. 14(6): p. 6701-6707., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686523/pdf/ol-14-06-6701.pdf

71. Gidley, P. W., Thompson, C. R., Roberts, D. B., Weber, R. S., The results of temporal bone surgery for advanced or recurrent tumors of the parotidgland, Laryngoscope, 2011. 121(8): p. 1702-7., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/lary.21867?download=true

72. Carlson, ML, Patel, NS, Modest, MC, Moore, EJ, Janus, JR, Olsen, KD, Occult Temporal Bone Facial Nerve Involvement by Parotid Malignancies with Perineural Spread., Otolaryngol Head Neck Surg, 2015. 153 (3)(3): p. 385-91., https://pubmed.ncbi.nlm.nih.gov/26129739/

73. Mantsopoulos, K, Velegrakis, S, Iro, H, Unexpected Detection of Parotid Gland Malignancy during Primary Extracapsular Dissection., Otolaryngol Head Neck Surg, 2015. 152 (6)(6): p. 1042-7., https://pubmed.ncbi.nlm.nih.gov/25820585/

74. Nnochiri, CC, Watkin, GT, Hobsley, M, Unremarkable parotid tumours that prove to be malignant., Br J Surg, 1990. 77 (8)(8): p. 917-8., https://pubmed.ncbi.nlm.nih.gov/2100985/

75. Park, H, Han, S, Park, SJ, Jung, YH, Ahn, SH, Jeong, WJ, Oncological outcomes of preoperatively unexpected malignant tumors of the parotid gland., Eur Arch Otorhinolaryngol, 2021. 278 (6)(6): p. 2033-2040., https://pubmed.ncbi.nlm.nih.gov/32862275/

76. Ryu, IS, Roh, JL, Cho, KJ, Lee, SW, Choi, SH, Nam, SY, et.al. Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions., Head Neck, 2013. 35 (12)(12): p. 1764-70., https://pubmed.ncbi.nlm.nih.gov/23483628/

77. Kaszuba, S. M., Zafereo, M. E., Rosenthal, D. I., El-Naggar, A. K., Weber, R. S., Effect of initial treatment on disease outcome for patients with submandibular gland carcinoma, Arch Otolaryngol Head Neck Surg, 2007. 133(6): p. 546-50., https://pubmed.ncbi.nlm.nih.gov/17576904/

78. Lombardi, D, Accorona, R, Lambert, A, Mercante, G, Coropciuc, R, Paderno, A, et.al. Long-term outcomes and prognosis in submandibular gland malignant tumors: A multicenter study., Laryngoscope, 2018. 128 (12)(12): p. 2745-2750., https://pubmed.ncbi.nlm.nih.gov/29756241/

79. Vander Poorten, V., Hunt, J., Bradley, P. J., Haigentz, M., Jr., Rinaldo, A., Mendenhall, W. M., et.al. Recent trends in the management of minor salivary gland carcinoma, Head Neck, 2014. 36(3): p. 444-55., https://pubmed.ncbi.nlm.nih.gov/23559518/

80. Park, SI, Park, W, Choi, S, Jang, Y, Kim, H, Kim, SH, et.al. Clinical Outcome of Minor Salivary Gland Cancers in the Oral Cavity: A Comparative Analysis With Squamous Cell Carcinomas of the Oral Cavity., Front Oncol, 2020. 10 (): p. 881., https://pubmed.ncbi.nlm.nih.gov/32582548/

81. Lombardi, D., McGurk, M., Vander Poorten, V., Guzzo, M., Accorona, R., Rampinelli, V., et.al. Surgical treatment of salivary malignant tumors, Oral Oncol, 2017. 65: p. 102-113., https://pubmed.ncbi.nlm.nih.gov/28017651/

82. He, J. F., Lin, Y., Wang, B., Zhu, W. Y., Wei, D., Zhu, H. Y., Analysis of the clinicopathological characteristics and prognosis of adenoid cystic carcinoma of the intraoral minor salivary glands: a retrospective study of 40 cases, Int J Oral Maxillofac Surg, 2021. 50(4): p. 444-450., https://pubmed.ncbi.nlm.nih.gov/32811708/

83. Lupinetti, A. D., Roberts, D. B., Williams, M. D., Kupferman, M. E., Rosenthal, D. I., Demonte, F., et.al. Sinonasal adenoid cystic carcinoma: the M. D. Anderson Cancer Center experience, Cancer, 2007. 110(12): p. 2726-31., https://pubmed.ncbi.nlm.nih.gov/17960615/

84. Ettl, T., Maligne Speicheldrüsentumoren, Der MKG-Chirurg, 2015. 8(3): p. 151-166., https://doi.org/10.1007/s12285-015-0016-3

85. Lim, CM, Gilbert, M, Johnson, JT, Kim, S, Is level V neck dissection necessary in primary parotid cancer?, Laryngoscope, 2015. 125 (1)(1): p. 118-21., https://pubmed.ncbi.nlm.nih.gov/24965707/

86. Ali, S, Palmer, FL, DiLorenzo, M, Shah, JP, Patel, SG, Ganly, I, Treatment of the neck in carcinoma of the parotid gland., Ann Surg Oncol, 2014. 21 (9)(9): p. 3042-8., https://pubmed.ncbi.nlm.nih.gov/24719019/

87. Armstrong, JG, Harrison, LB, Thaler, HT, Friedlander-Klar, H, Fass, DE, Zelefsky, MJ, et.al. The indications for elective treatment of the neck in cancer of the major salivary glands., Cancer, 1992. 69 (3)(3): p. 615-9., https://pubmed.ncbi.nlm.nih.gov/1730113/

88. Jinnin, T, Kawata, R, Higashino, M, Nishikawa, S, Terada, T, Haginomori, SI, Patterns of lymph node metastasis and the management of neck dissection for parotid carcinomas: a single-institute experience., Int J Clin Oncol, 2019. 24 (6)(6): p. 624-631., https://pubmed.ncbi.nlm.nih.gov/30739264/

89. Otsuka, K., Imanishi, Y., Tada, Y., Kawakita, D., Kano, S., Tsukahara, K., et.al. Clinical Outcomes and Prognostic Factors for Salivary Duct Carcinoma: A Multi-InstitutionalAnalysis of 141 Patients, Ann Surg Oncol, 2016. 23(6): p. 2038-45., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858547/pdf/10434_2015_Article_5082.pdf

90. Harbison, R. A., Gray, A. J., Westling, T., Carone, M., Rodriguez, C. P., Futran, N. D., et.al. The role of elective neck dissection in high-grade parotid malignancy: A hospital-basedcohort study, Laryngoscope, 2019., https://pubmed.ncbi.nlm.nih.gov/31468551/

91. Kaura, A., Kennedy, R. A., Ali, S., Odell, E., Simo, R., Jeannon, J. P., et.al. Utility of neck dissection for management of carcinoma of the parotid gland, Br J Oral Maxillofac Surg, 2019., https://pubmed.ncbi.nlm.nih.gov/31564483/

92. Luksic, I, Suton, P, Elective neck dissection in adenoid cystic carcinoma of head and neck: yes or no? A systematic review., Eur Arch Otorhinolaryngol, 2019. 276 (11)(11): p. 2957-2962., https://pubmed.ncbi.nlm.nih.gov/31583431/

93. Xiao, R, Sethi, RKV, Feng, AL, Fontanarosa, JB, Deschler, DG, The role of elective neck dissection in patients with adenoid cystic carcinoma of the head and neck., Laryngoscope, 2019. 129 (9)(9): p. 2094-2104., https://pubmed.ncbi.nlm.nih.gov/30667061/

94. Ettl, T, Gosau, M, Brockhoff, G, Schwarz-Furlan, S, Agaimy, A, Reichert, TE, et.al. Predictors of cervical lymph node metastasis in salivary gland cancer., Head Neck, 2014. 36 (4)(4): p. 517-23., https://pubmed.ncbi.nlm.nih.gov/23780687/

95. Nobis, CP, Rohleder, NH, Wolff, KD, Wagenpfeil, S, Scherer, EQ, Kesting, MR, Head and neck salivary gland carcinomas--elective neck dissection, yes or no?, J Oral Maxillofac Surg, 2014. 72 (1)(1): p. 205-10., https://pubmed.ncbi.nlm.nih.gov/23891016/

96. Jayaprakash, V, Merzianu, M, Warren, GW, Arshad, H, Hicks, WL, Rigual, NR, et.al. Survival rates and prognostic factors for infiltrating salivary duct carcinoma: Analysis of 228 cases from the Surveillance, Epidemiology, and End Results database., Head Neck, 2014. 36 (5)(5): p. 694-701., https://pubmed.ncbi.nlm.nih.gov/23606370/

97. Zbären, P, Schüpbach, J, Nuyens, M, Stauffer, E, Elective neck dissection versus observation in primary parotid carcinoma., Otolaryngol Head Neck Surg, 2005. 132 (3)(3): p. 387-91., https://pubmed.ncbi.nlm.nih.gov/15746848/

98. Valstar, MH, van den Brekel, MW, Smeele, LE, Interpretation of treatment outcome in the clinically node-negative neck in primary parotid carcinoma: a systematic review of the literature., Head Neck, 2010. 32 (10)(10): p. 1402-11., https://pubmed.ncbi.nlm.nih.gov/20029981/

99. Lau, VH, Aouad, R, Farwell, DG, Donald, PJ, Chen, AM, Patterns of nodal involvement for clinically N0 salivary gland carcinoma: refining the role of elective neck irradiation., Head Neck, 2014. 36 (10)(10): p. 1435-9., https://pubmed.ncbi.nlm.nih.gov/24038533/

100. Stennert, E, Kisner, D, Jungehuelsing, M, Guntinas-Lichius, O, Schröder, U, Eckel, HE, et.al. High incidence of lymph node metastasis in major salivary gland cancer., Arch Otolaryngol Head Neck Surg, 2003. 129 (7)(7): p. 720-3., https://pubmed.ncbi.nlm.nih.gov/12874071/

101. Zhang, CY, Xia, RH, Han, J, Wang, BS, Tian, WD, Zhong, LP, et.al. Adenoid cystic carcinoma of the head and neck: clinicopathologic analysis of 218 cases in a Chinese population., Oral Surg Oral Med Oral Pathol Oral Radiol, 2013. 115 (3)(3): p. 368-75., https://pubmed.ncbi.nlm.nih.gov/23453028/

102. Hellquist, H, Skálová, A, Barnes, L, Cardesa, A, Thompson, LD, Triantafyllou, A, et.al. Cervical Lymph Node Metastasis in High-Grade Transformation of Head and Neck Adenoid Cystic Carcinoma: A Collective International Review., Adv Ther, 2016. 33 (3)(3): p. 357-68., https://pubmed.ncbi.nlm.nih.gov/26895332/

103. Suton, P, Luksic, I, Prognostic value of elective neck dissection in adenoid cystic carcinoma of head and neck: a meta-analysis: A call for randomized trials and international consensus., Int J Oral Maxillofac Surg, 2021. 50 (11)(11): p. 1403-1407., https://pubmed.ncbi.nlm.nih.gov/33602647/

104. Mc Loughlin, L., Gillanders, S. L., Smith, S., Young, O., The role of adjuvant radiotherapy in management of recurrent pleomorphic adenomaof the parotid gland: a systematic review, European Archives of Oto-Rhino-Laryngology, 2019. 276(2): p. 283-295., https://link.springer.com/content/pdf/10.1007/s00405-018-5205-z.pdf

105. Mannelli, G, Comini, LV, Sacchetto, A, Santoro, R, Spinelli, G, Bonomo, P, et.al. Estimating survival after salvage surgery for recurrent salivary gland cancers: Systematic review., Head Neck, 2022. 44 (8)(8): p. 1961-1975., https://pubmed.ncbi.nlm.nih.gov/35441406/

106. Hintze, JM, O'Duffy, F, White-Gibson, A, O'Neill, P, Kinsella, J, Timon, C, et.al. Supporting the use of adjuvant radiotherapy in recurrent pleomorphic adenoma of the parotid., Acta Otolaryngol, 2021. 141 (10)(10): p. 971-976., https://pubmed.ncbi.nlm.nih.gov/34622733/

107. Patel, S, Mourad, WF, Wang, C, Dhanireddy, B, Concert, C, Ryniak, M, et.al. Postoperative radiation therapy for parotid pleomorphic adenoma with close or positive margins: treatment outcomes and toxicities., Anticancer Res, 2014. 34 (8)(8): p. 4247-51., https://pubmed.ncbi.nlm.nih.gov/25075054/

108. Armstrong, J. G., Harrison, L. B., Spiro, R. H., Fass, D. E., Strong, E. W., Fuks, Z. Y., Malignant tumors of major salivary gland origin. A matched-pair analysis of the role of combined surgery and postoperative radiotherapy, Arch Otolaryngol Head Neck Surg, 1990. 116(3): p. 290-3., http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2306346

109. Noh, J. M., Ahn, Y. C., Nam, H., Park, W., Baek, C. H., Son, Y. I., et.al. Treatment Results of Major Salivary Gland Cancer by Surgery with or without Postoperative Radiation Therapy, Clin Exp Otorhinolaryngol, 2010. 3(2): p. 96-101., http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20607079

110. Schmid, M. P., Held, T., Lang, K., Herfarth, K., Hörner-Rieber, J., Harrabi, S. B., et.al. Intensity Modulated Radiotherapy with Carbon Ion Radiotherapy Boost for Acinic Cell Carcinoma of the Salivary Glands, Cancers (Basel), 2021. 13(1):, https://pubmed.ncbi.nlm.nih.gov/33401730/

111. Terhaard, CH, Lubsen, H, Van der Tweel, I, Hilgers, FJ, Eijkenboom, WM, Marres, HA, et.al. Salivary gland carcinoma: independent prognostic factors for locoregional control, distant metastases, and overall survival: results of the Dutch head and neck oncology cooperative group., Head Neck, 2004. 26 (8)(8): p. 681-92; discussion 692-3., https://pubmed.ncbi.nlm.nih.gov/15287035/

112. Terhaard, CH, Lubsen, H, Rasch, CR, Levendag, PC, Kaanders, HH, Tjho-Heslinga, RE, et.al. The role of radiotherapy in the treatment of malignant salivary gland tumors., Int J Radiat Oncol Biol Phys, 2005. 61 (1)(1): p. 103-11., https://pubmed.ncbi.nlm.nih.gov/15629600/

113. Safdieh, J, Givi, B, Osborn, V, Lederman, A, Schwartz, D, Schreiber, D, Impact of Adjuvant Radiotherapy for Malignant Salivary Gland Tumors., Otolaryngol Head Neck Surg, 2017. 157 (6)(6): p. 988-994., https://pubmed.ncbi.nlm.nih.gov/28675085/

114. Mahmood, U, Koshy, M, Goloubeva, O, Suntharalingam, M, Adjuvant radiation therapy for high-grade and/or locally advanced major salivary gland tumors., Arch Otolaryngol Head Neck Surg, 2011. 137 (10)(10): p. 1025-30., https://pubmed.ncbi.nlm.nih.gov/22006781/

115. Garden, AS, Weber, RS, Morrison, WH, Ang, KK, Peters, LJ, The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation., Int J Radiat Oncol Biol Phys, 1995. 32 (3)(3): p. 619-26., https://pubmed.ncbi.nlm.nih.gov/7790247/

116. Bjørndal, K, Krogdahl, A, Therkildsen, MH, Charabi, B, Kristensen, CA, Andersen, E, et.al. Salivary adenoid cystic carcinoma in Denmark 1990-2005: Outcome and independent prognostic factors including the benefit of radiotherapy. Results of the Danish Head and Neck Cancer Group (DAHANCA)., Oral Oncol, 2015. 51 (12)(12): p. 1138-42., https://pubmed.ncbi.nlm.nih.gov/26476712/

117. Lee, A, Givi, B, Osborn, VW, Schwartz, D, Schreiber, D, Patterns of care and survival of adjuvant radiation for major salivary adenoid cystic carcinoma., Laryngoscope, 2017. 127 (9)(9): p. 2057-2062., https://pubmed.ncbi.nlm.nih.gov/28194862/

118. North, L, Stadler, M, Massey, B, Campbell, B, Shukla, M, Awan, M, et.al. Intermediate-grade carcinoma of the parotid and the impact of adjuvant radiation., Am J Otolaryngol 40 (6)(6): p. 102282., https://pubmed.ncbi.nlm.nih.gov/31519432/

119. Zenga, J, Yu, Z, Parikh, A, Chen, JX, Lin, DT, Emerick, KS, et.al. Mucoepidermoid Carcinoma of the Parotid: Very Close Margins and Adjuvant Radiotherapy., ORL J Otorhinolaryngol Relat Spec 81 (1)(1): p. 55-62., https://pubmed.ncbi.nlm.nih.gov/30939481/

120. Zenga, J, Parikh, AS, Emerick, KS, Lin, DT, Faquin, WC, Deschler, DG, Close Margins and Adjuvant Radiotherapy in Acinic Cell Carcinoma of the Parotid Gland., JAMA Otolaryngol Head Neck Surg, 2018. 144 (11)(11): p. 1011-1016., https://pubmed.ncbi.nlm.nih.gov/29978180/

121. von der Grün, J, Rödel, C, Semrau, S, Balermpas, P, Martin, D, Fietkau, R, et.al. Patterns of care analysis for salivary gland cancer: a survey within the German Society of Radiation Oncology (DEGRO) and recommendations for daily practice., Strahlenther Onkol, 2022. 198 (2)(2): p. 123-134., https://pubmed.ncbi.nlm.nih.gov/34427717/

122. Hsieh, CE, Lee, LY, Chou, YC, Fan, KH, Tsang, NM, Chang, JT, et.al. Nodal failure patterns and utility of elective nodal irradiation in submandibular gland carcinoma treated with postoperative radiotherapy - a multicenter experience., Radiat Oncol, 2018. 13 (1)(1): p. 184., https://pubmed.ncbi.nlm.nih.gov/30241545/

123. Chen, AM, Garcia, J, Granchi, P, Bucci, MK, Lee, NY, Base of skull recurrences after treatment of salivary gland cancer with perineural invasion reduced by postoperative radiotherapy., Clin Otolaryngol, 2009. 34 (6)(6): p. 539-45., https://pubmed.ncbi.nlm.nih.gov/20070763/

124. Kordzińska-Cisek, I, Cisek, P, Grzybowska-Szatkowska, L, The Role of Prognostic Factors in Salivary Gland Tumors Treated by Surgery and Adjuvant Radio- or Chemoradiotherapy - A Single Institution Experience., Cancer Manag Res, 2020. 12 (): p. 1047-1067., https://pubmed.ncbi.nlm.nih.gov/32104086/

125. Haderlein, M, Scherl, C, Semrau, S, Lettmaier, S, Hecht, M, Putz, F, et.al. Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin - high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis., Radiat Oncol, 2019. 14 (1)(1): p. 68., https://pubmed.ncbi.nlm.nih.gov/31014362/

126. Mendenhall, WM, Morris, CG, Amdur, RJ, Werning, JW, Hinerman, RW, Villaret, DB, Radiotherapy alone or combined with surgery for adenoid cystic carcinoma of the head and neck., Head Neck, 2004. 26 (2)(2): p. 154-62., https://pubmed.ncbi.nlm.nih.gov/14762884/

127. Mendenhall, WM, Morris, CG, Amdur, RJ, Werning, JW, Villaret, DB, Radiotherapy alone or combined with surgery for salivary gland carcinoma., Cancer, 2005. 103 (12)(12): p. 2544-50., https://pubmed.ncbi.nlm.nih.gov/15880750/

128. Chen, AM, Garcia, J, Lee, NY, Bucci, MK, Eisele, DW, Patterns of nodal relapse after surgery and postoperative radiation therapy for carcinomas of the major and minor salivary glands: what is the role of elective neck irradiation?, Int J Radiat Oncol Biol Phys, 2007. 67 (4)(4): p. 988-94., https://pubmed.ncbi.nlm.nih.gov/17234357/

129. Nutting, CM, Morden, JP, Beasley, M, Bhide, S, Cook, A, De Winton, E, et.al. Results of a multicentre randomised controlled trial of cochlear-sparing intensity-modulated radiotherapy versus conventional radiotherapy in patients with parotid cancer (COSTAR; CRUK/08/004)., Eur J Cancer, 2018. 103 (): p. 249-258., https://pubmed.ncbi.nlm.nih.gov/30286418/

130. Jensen, AD, Poulakis, M, Nikoghosyan, AV, Welzel, T, Uhl, M, Federspil, PA, et.al. High-LET radiotherapy for adenoid cystic carcinoma of the head and neck: 15 years' experience with raster-scanned carbon ion therapy., Radiother Oncol, 2016. 118 (2)(2): p. 272-80., https://pubmed.ncbi.nlm.nih.gov/26164774/

131. Karam, SD, Rashid, A, Snider, JW, Wooster, M, Bhatia, S, Jay, AK, et.al. IMRT with Stereotactic Body Radiotherapy Boost for High Risk Malignant Salivary Gland Malignancies: A Case Series., Front Oncol, 2014. 4 (): p. 268., https://pubmed.ncbi.nlm.nih.gov/25374840/

132. Zakeri, K., Wang, H., Kang, J. J., Lee, A., Romesser, P., Mohamed, N., et.al. Outcomes and prognostic factors of major salivary gland tumors treated with proton beam radiation therapy, Head Neck, 2021. 43(4): p. 1056-1062., https://pubmed.ncbi.nlm.nih.gov/33606323/

133. Karam, S. D., Snider, J. W., Wang, H., Wooster, M., Lominska, C., Deeken, J., et.al. Reirradiation of recurrent salivary gland malignancies with fractionated stereotacticbody radiation therapy, J Radiat Oncol, 2012. 1(2): p. 147-153., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573714/pdf/13566_2012_Article_10.pdf

134. Chen, A. M., Garcia, J., Granchi, P. J., Johnson, J., Eisele, D. W., Late recurrence from salivary gland cancer: when does "cure" mean cure?, Cancer, 2008. 112(2): p. 340-4., https://pubmed.ncbi.nlm.nih.gov/18008358/

135. S3-Leitlinie Diagnostik und Therapie des Mundhöhlenkarzinoms,, AWMF-Registernummer 007/100OL, 2021. Version 3.0:

136. Lee, S. H., Roh, J. L., Kim, J. S., Lee, J. H., Choi, S. H., Nam, S. Y., et.al. Detection of distant metastasis and prognostic prediction of recurrent salivary glandcarcinomas using (18) F-FDG PET/CT, Oral Dis, 2018. 24(6): p. 940-947., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/odi.12877?download=true

137. Razfar, A., Heron, D. E., Branstetter, B. F. th, Seethala, R. R., Ferris, R. L., Positron emission tomography-computed tomography adds to the management of salivarygland malignancies, Laryngoscope, 2010. 120(4): p. 734-8., https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/lary.20829?download=true

138. Li, B. B., Xie, X. Y., Jia, S. N., A case-cohort study of recurrent salivary adenoid cystic carcinoma after iodine 125brachytherapy and resection treatment, Annals of Diagnostic Pathology, 2015. 19(1): p. 1-5., https://www.sciencedirect.com/science/article/abs/pii/S1092913414001270?via%3Dihub

139. Girelli, L, Locati, L, Galeone, C, Scanagatta, P, Duranti, L, Licitra, L, et.al. Lung metastasectomy in adenoid cystic cancer: Is it worth it?, Oral Oncol, 2017. 65 (): p. 114-118., https://pubmed.ncbi.nlm.nih.gov/28341276/

140. Mimica, X, McGill, M, Hay, A, Karassawa Zanoni, D, Shah, JP, Wong, RJ, et.al. Distant metastasis of salivary gland cancer: Incidence, management, and outcomes., Cancer, 2020. 126 (10)(10): p. 2153-2162., https://pubmed.ncbi.nlm.nih.gov/32097509/

141. Locati, LD, Guzzo, M, Bossi, P, Massone, PP, Conti, B, Fumagalli, E, et.al. Lung metastasectomy in adenoid cystic carcinoma (ACC) of salivary gland., Oral Oncol, 2005. 41 (9)(9): p. 890-4., https://pubmed.ncbi.nlm.nih.gov/16043380/

142. Jegadeesh, N, Liu, Y, Prabhu, RS, Magliocca, KR, Marcus, DM, Higgins, KA, et.al. Outcomes and prognostic factors in modern era management of major salivary gland cancer., Oral Oncol, 2015. 51 (8)(8): p. 770-7., https://pubmed.ncbi.nlm.nih.gov/26033470/

143. Shi, X, Dong, F, Wei, W, Song, K, Huang, N, Lu, Z, et.al. Prognostic significance and optimal candidates of primary tumor resection in major salivary gland carcinoma patients with distant metastases at initial presentation: A population-based study., Oral Oncol, 2018. 78 (): p. 87-93., https://pubmed.ncbi.nlm.nih.gov/29496064/

144. Ellington, CL, Goodman, M, Kono, SA, Grist, W, Wadsworth, T, Chen, AY, et.al. Adenoid cystic carcinoma of the head and neck: Incidence and survival trends based on 1973-2007 Surveillance, Epidemiology, and End Results data., Cancer, 2012. 118 (18)(18): p. 4444-51., https://pubmed.ncbi.nlm.nih.gov/22294420/

145. Spiro, RH, Distant metastasis in adenoid cystic carcinoma of salivary origin., Am J Surg, 1997. 174 (5)(5): p. 495-8., https://pubmed.ncbi.nlm.nih.gov/9374223/

146. Rajasekaran, K, Stubbs, V, Chen, J, Yalamanchi, P, Cannady, S, Brant, J, et.al. Mucoepidermoid carcinoma of the parotid gland: A National Cancer Database study., Am J Otolaryngol 39 (3)(3): p. 321-326., https://pubmed.ncbi.nlm.nih.gov/29559174/

147. Lievens, Y, Guckenberger, M, Gomez, D, Hoyer, M, Iyengar, P, Kindts, I, et.al. Defining oligometastatic disease from a radiation oncology perspective: An ESTRO-ASTRO consensus document., Radiother Oncol, 2020. 148 (): p. 157-166., https://pubmed.ncbi.nlm.nih.gov/32388150/

148. Florescu, C, Thariat, J, Local ablative treatments of oligometastases from head and neck carcinomas., Crit Rev Oncol Hematol, 2014. 91 (1)(1): p. 47-63., https://pubmed.ncbi.nlm.nih.gov/24556572/

149. Franceschini, D, De Rose, F, Franzese, C, Comito, T, Di Brina, L, Radicioni, G, et.al. Predictive Factors for Response and Survival in a Cohort of Oligometastatic Patients Treated With Stereotactic Body Radiation Therapy., Int J Radiat Oncol Biol Phys, 2019. 104 (1)(1): p. 111-121., https://pubmed.ncbi.nlm.nih.gov/30630030/

150. Pasalic, D, Lu, Y, Betancourt-Cuellar, SL, Taku, N, Mesko, SM, Bagley, AF, et.al. Stereotactic ablative radiation therapy for pulmonary metastases: Improving overall survival and identifying subgroups at high risk of local failure., Radiother Oncol, 2020. 145 (): p. 178-185., https://pubmed.ncbi.nlm.nih.gov/32044530/

151. Palma, DA, Olson, R, Harrow, S, Gaede, S, Louie, AV, Haasbeek, C, et.al. Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized Trial., J Clin Oncol, 2020. 38 (25)(25): p. 2830-2838., https://pubmed.ncbi.nlm.nih.gov/32484754/

152. Fitzpatrick, P.J, Theriault, C, Malignant salivary gland tumors, 1986. 12(10): p. 1743 - 1747., https://www.sciencedirect.com/science/article/pii/0360301686903147

153. Laramore, GE, Krall, JM, Griffin, TW, Duncan, W, Richter, MP, Saroja, KR, et.al. Neutron versus photon irradiation for unresectable salivary gland tumors: final report of an RTOG-MRC randomized clinical trial. Radiation Therapy Oncology Group. Medical Research Council., Int J Radiat Oncol Biol Phys, 1993. 27 (2)(2): p. 235-40., https://pubmed.ncbi.nlm.nih.gov/8407397/

154. Stannard, C, Vernimmen, F, Carrara, H, Jones, D, Fredericks, S, Hille, J, et.al. Malignant salivary gland tumours: can fast neutron therapy results point the way to carbon ion therapy?, Radiother Oncol, 2013. 109 (2)(2): p. 262-8., https://pubmed.ncbi.nlm.nih.gov/24044797/

155. Jensen, AD, Nikoghosyan, AV, Poulakis, M, Höss, A, Haberer, T, Jäkel, O, et.al. Combined intensity-modulated radiotherapy plus raster-scanned carbon ion boost for advanced adenoid cystic carcinoma of the head and neck results in superior locoregional control and overall survival., Cancer, 2015. 121 (17)(17): p. 3001-9., https://pubmed.ncbi.nlm.nih.gov/26043145/

156. Holtzman, A, Morris, CG, Amdur, RJ, Dziegielewski, PT, Boyce, B, Mendenhall, WM, Outcomes after primary or adjuvant radiotherapy for salivary gland carcinoma., Acta Oncol, 2017. 56 (3)(3): p. 484-489., https://pubmed.ncbi.nlm.nih.gov/27846763/

157. Vikram, B, Strong, EW, Shah, JP, Spiro, RH, Radiation therapy in adenoid-cystic carcinoma., Int J Radiat Oncol Biol Phys, 1984. 10 (2)(2): p. 221-3., https://pubmed.ncbi.nlm.nih.gov/6323361/

158. Vischioni, B, Dhanireddy, B, Severo, C, Bonora, M, Ronchi, S, Vitolo, V, et.al. Reirradiation of salivary gland tumors with carbon ion radiotherapy at CNAO., Radiother Oncol, 2020. 145 (): p. 172-177., https://pubmed.ncbi.nlm.nih.gov/32044529/

159. Franzese, C, Badalamenti, M, Teriaca, A, De Virgilio, A, Mercante, G, Cavina, R, et.al. Metastasis-directed stereotactic body radiation therapy in the management of oligometastatic head and neck cancer., J Cancer Res Clin Oncol, 2021. 147 (5)(5): p. 1307-1313., https://pubmed.ncbi.nlm.nih.gov/33471186/

160. Franzese, C, Ingargiola, R, Tomatis, S, Iacovelli, NA, Beltramo, G, Franco, P, et.al. Metastatic salivary gland carcinoma: A role for stereotactic body radiation therapy? A study of AIRO-Head and Neck working group., Oral Dis, 2022. 28 (2)(2): p. 345-351., https://pubmed.ncbi.nlm.nih.gov/33320410/

161. Gebhardt, B. J., Ohr, J. P., Ferris, R. L., Duvvuri, U., Kim, S., Johnson, J. T., et.al. Concurrent Chemoradiotherapy in the Adjuvant Treatment of High-risk Primary Salivary Gland Malignancies, Am J Clin Oncol, 2018. 41(9): p. 888-893., https://pubmed.ncbi.nlm.nih.gov/28394767/

162. Aro, K., Ho, A. S., Luu, M., Kim, S., Tighiouart, M., Yoshida, E. J., et.al. Survival Impact of Adjuvant Therapy in Salivary Gland Cancers following Resection and Neck Dissection, Otolaryngol Head Neck Surg, 2019. 160(6): p. 1048-1057., https://pubmed.ncbi.nlm.nih.gov/30721113/

163. Hsieh, C. E., Lin, C. Y., Lee, L. Y., Yang, L. Y., Wang, C. C., Wang, H. M., et.al. Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study, Radiat Oncol, 2016. 11: p. 47., https://pubmed.ncbi.nlm.nih.gov/27000157/

164. Swain, M, Ghosh-Laskar, S, Budrukkar, A, Patil, R, Murthy, V, Gupta, T, et.al. Concurrent chemoradiotherapy for locally advanced unresectable adenoid cystic carcinoma of head and neck: experience from a single institute., Eur Arch Otorhinolaryngol, 2021. 278 (11)(11): p. 4423-4431., https://pubmed.ncbi.nlm.nih.gov/33564909/

165. Jensen, AD, Poulakis, M, Nikoghosyan, AV, Chaudhri, N, Uhl, M, Münter, MW, et.al. Re-irradiation of adenoid cystic carcinoma: analysis and evaluation of outcome in 52 consecutive patients treated with raster-scanned carbon ion therapy., Radiother Oncol, 2015. 114 (2)(2): p. 182-8., https://pubmed.ncbi.nlm.nih.gov/25640299/

166. Samant, S, van den Brekel, MW, Kies, MS, Wan, J, Robbins, KT, Rosenthal, DI, et.al. Concurrent chemoradiation for adenoid cystic carcinoma of the head and neck., Head Neck, 2012. 34 (9)(9): p. 1263-8., https://pubmed.ncbi.nlm.nih.gov/22083968/

167. Jhaveri, KL, Wang, XV, Makker, V, Luoh, SW, Mitchell, EP, Zwiebel, JA, et.al. Ado-trastuzumab emtansine (T-DM1) in patients with HER2-amplified tumors excluding breast and gastric/gastroesophageal junction (GEJ) adenocarcinomas: results from the NCI-MATCH trial (EAY131) subprotocol Q., Ann Oncol, 2019. 30 (11)(11): p. 1821-1830., https://pubmed.ncbi.nlm.nih.gov/31504139/

168. Drilon, A, Laetsch, TW, Kummar, S, DuBois, SG, Lassen, UN, Demetri, GD, et.al. Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children., N Engl J Med, 2018. 378 (8)(8): p. 731-739., https://pubmed.ncbi.nlm.nih.gov/29466156/

169. Takahashi, H., Tada, Y., Saotome, T., Akazawa, K., Ojiri, H., Fushimi, C., et.al. Phase II Trial of Trastuzumab and Docetaxel in Patients With Human Epidermal Growth Factor Receptor 2-Positive Salivary Duct Carcinoma, J Clin Oncol, 2019. 37(2): p. 125-134., https://pubmed.ncbi.nlm.nih.gov/30452336/

170. Kurzrock, R., Bowles, D. W., Kang, H., Meric-Bernstam, F., Hainsworth, J., Spigel, D. R., et.al. Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study, Ann Oncol, 2020. 31(3): p. 412-421., https://pubmed.ncbi.nlm.nih.gov/32067683/

171. Fushimi, C., Tada, Y., Takahashi, H., Nagao, T., Ojiri, H., Masubuchi, T., et.al. A prospective phase II study of combined androgen blockade in patients with androgen receptor-positive metastatic or locally advanced unresectable salivary gland carcinoma, Ann Oncol, 2018. 29(4): p. 979-984., https://pubmed.ncbi.nlm.nih.gov/29211833/

172. Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft (DKG) e.V., Stiftung Deutsche Krebshilfe (DKH), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V.), Entwicklung von leitlinienbasierten Qualitätsindikatoren. Methodenpapier für das Leitlinienprogramm Onkologie, 2021. Version 3.0:, https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Methodik/QIEP_OL_2021_Version_3.0_.pdf