Leitlinienprogramm OnkologieKlinische Ernährung in der Onkologie

13. Literaturverzeichnis – Klinische Ernährung in der Onkologie

Version 1.0 · Januar 2026 · AWMF 073 - 006OL
Leitlinienprogramm Onkologie · Deutsche Krebsgesellschaft · Deutsche Krebshilfe · AWMF

1. Arends, J., Bertz, H., Bischoff, S. C., Fietkau, R., Herrmann, H. J., Holm, E., et.al. S3-Leitline der Deutschen Gesellschaft für Ernährungsmedizin e. V. (DGEM) in Kooperation mit der Deutschen Gesellschaft für Hämatologie und Onkologie e.V. (DGHO), der Arbeitsgemeinschaft Supportive Maßnahmen in der Onkologie, Rehabilitation und Sozialmedizin der Deutschen Krebsgesellschaft (ASORS) und der Österreichischen Arbeitsgemeinschaft für klinische Ernährung (AKE), Klinische Ernährung in der Onkologie, 2015. 40(05): p. e1-e74., http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1552741, https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0035-1552741.pdf

2. Kondrup, J, Rasmussen, HH, Hamberg, O, Stanga, Z, Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials., Clin Nutr, 2003. 22 (3)(3): p. 321-36., https://pubmed.ncbi.nlm.nih.gov/12765673/

3. Boléo-Tomé, C, Monteiro-Grillo, I, Camilo, M, Ravasco, P, Validation of the Malnutrition Universal Screening Tool (MUST) in cancer., Br J Nutr, 2012. 108 (2)(2): p. 343-8., https://pubmed.ncbi.nlm.nih.gov/22142968/

4. Ferguson, ML, Bauer, J, Gallagher, B, Capra, S, Christie, DR, Mason, BR, Validation of a malnutrition screening tool for patients receiving radiotherapy., Australas Radiol, 1999. 43 (3)(3): p. 325-7., https://pubmed.ncbi.nlm.nih.gov/10901927/

5. Detsky, AS, McLaughlin, JR, Baker, JP, Johnston, N, Whittaker, S, Mendelson, RA, et.al. What is subjective global assessment of nutritional status?, JPEN J Parenter Enteral Nutr, 1987. 11 (1)(1): p. 8-13., https://pubmed.ncbi.nlm.nih.gov/3820522/

6. Erickson, N, Storck, LJ, Kolm, A, Norman, K, Fey, T, Schiffler, V, et.al. Tri-country translation, cultural adaptation, and validity confirmation of the Scored Patient-Generated Subjective Global Assessment., Support Care Cancer, 2019. 27 (9)(9): p. 3499-3507., https://pubmed.ncbi.nlm.nih.gov/30684046/

7. Vellas, B, Guigoz, Y, Garry, PJ, Nourhashemi, F, Bennahum, D, Lauque, S, et.al. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients., Nutrition, 1999. 15 (2)(2): p. 116-22., https://pubmed.ncbi.nlm.nih.gov/9990575/

8. Rubenstein, LZ, Harker, JO, Salvà, A, Guigoz, Y, Vellas, B, Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF)., J Gerontol A Biol Sci Med Sci, 2001. 56 (6)(6): p. M366-72., https://pubmed.ncbi.nlm.nih.gov/11382797/

9. Koula-Jenik, H, Miko, M, Kraft, M, Schulz, RJ, Leitfaden Ernährungsmedizin, 2005.

10. Schauder, P, Ollenschläger, G, Ernährungsmedizin - Prävention und Therapie, 2006.

11. Verband der Diätassistenten - Deutscher Bundesverband e.V., Manual für den German-Nutrition Care Process (G-NCP). Ein Standardwerk für die Durchführung, Weiterentwicklung, Überprüfung und Qualitätssicherung der Diätetik in Deutschland., VDD-Leitlinie für die Ernährungstherapie und das prozessgeleitete Handeln in der Diätetik, 2015., https://www.vdd.de/fuer-experten/german-nutrition-care-process/

12. Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft (DKG) e.V., Stiftung Deutsche Krebshilfe (DKH), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V.), Psychoonkologische Diagnostik, Beratung und Behandlung von erwachsenen Krebspatient*innen, Langversion 2.1, AWMF-Registernummer: 032-051OL, 2023 (abgerufen am: 27.11.2025)., https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Psychoonkologie/Version_2/LL_Psychoonkologie_Langversion_2.1.pdf

13. Bundesärztekammer (BÄK), Kassenärztliche Bundesvereinigung (KBV), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF), Nationale VersorgungsLeitlinie Unipolare Depression, Langfassung, Version 3.2, 2023 (abgerufen am: 27.11.2025)., https://register.awmf.org/assets/guidelines/nvl-005l_S3_Unipolare-Depression_2023-07.pdf

14. DiMatteo, MR, Lepper, HS, Croghan, TW, Depression is a risk factor for noncompliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence., Arch Intern Med, 2000. 160 (14)(14): p. 2101-7., https://pubmed.ncbi.nlm.nih.gov/10904452/

15. Weis, J, Giesler, JM, Standards in der psychosozialen Versorgung von Krebspatienten, Der Onkologe, 2016. p. 198 - 205., https://link.springer.com/article/10.1007/s00761-015-2938-9

16. Isenring, EA, Capra, S, Bauer, JD, Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area., Br J Cancer, 2004. 91 (3)(3): p. 447-52., https://pubmed.ncbi.nlm.nih.gov/15226773/

17. Ravasco, P, Monteiro-Grillo, I, Marques Vidal, P, Camilo, ME, Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy., Head Neck, 2005. 27 (8)(8): p. 659-68., https://pubmed.ncbi.nlm.nih.gov/15920748/

18. Ravasco, P, Monteiro-Grillo, I, Vidal, PM, Camilo, ME, Dietary counseling improves patient outcomes: a prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy., J Clin Oncol, 2005. 23 (7)(7): p. 1431-8., https://pubmed.ncbi.nlm.nih.gov/15684319/

19. van den Berg, MG, Rasmussen-Conrad, EL, Wei, KH, Lintz-Luidens, H, Kaanders, JH, Merkx, MA, Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy., Br J Nutr, 2010. 104 (6)(6): p. 872-7., https://pubmed.ncbi.nlm.nih.gov/20441684/

20. Ligthart-Melis, GC, Weijs, PJ, te Boveldt, ND, Buskermolen, S, Earthman, CP, Verheul, HM, et.al. Dietician-delivered intensive nutritional support is associated with a decrease in severe postoperative complications after surgery in patients with esophageal cancer., Dis Esophagus, 2013. 26 (6)(6): p. 587-93., https://pubmed.ncbi.nlm.nih.gov/23237356/

21. Poulsen, GM, Pedersen, LL, Østerlind, K, Bæksgaard, L, Andersen, JR, Randomized trial of the effects of individual nutritional counseling in cancer patients., Clin Nutr, 2014. 33 (5)(5): p. 749-53., https://pubmed.ncbi.nlm.nih.gov/24269077/

22. Potter, J, Langhorne, P, Roberts, M, Routine protein energy supplementation in adults: systematic review., BMJ, 1998. 317 (7157)(7157): p. 495-501., https://pubmed.ncbi.nlm.nih.gov/9712593/

23. Ravasco, P, Monteiro-Grillo, I, Camilo, M, Individualized nutrition intervention is of major benefit to colorectal cancer patients: long-term follow-up of a randomized controlled trial of nutritional therapy., Am J Clin Nutr, 2012. 96 (6)(6): p. 1346-53., https://pubmed.ncbi.nlm.nih.gov/23134880/

24. Baldwin, C, Spiro, A, McGough, C, Norman, AR, Gillbanks, A, Thomas, K, et.al. Simple nutritional intervention in patients with advanced cancers of the gastrointestinal tract, non-small cell lung cancers or mesothelioma and weight loss receiving chemotherapy: a randomised controlled trial., J Hum Nutr Diet, 2011. 24 (5)(5): p. 431-40., https://pubmed.ncbi.nlm.nih.gov/21733143/

25. Zhang, F, Jin, Y, Qiang, W, The effects of dietary advice on malnutrition in Cancer patients: a systematic review and meta-analysis., Support Care Cancer, 2020. 28 (4)(4): p. 1579-1585., https://pubmed.ncbi.nlm.nih.gov/31836940/

26. Lee, JLC, Leong, LP, Lim, SL, Nutrition intervention approaches to reduce malnutrition in oncology patients: a systematic review., Support Care Cancer, 2016. 24 (1)(1): p. 469-480., https://pubmed.ncbi.nlm.nih.gov/26404858/

27. de van der Schueren, MAE, Laviano, A, Blanchard, H, Jourdan, M, Arends, J, Baracos, VE, Systematic review and meta-analysis of the evidence for oral nutritional intervention on nutritional and clinical outcomes during chemo(radio)therapy: current evidence and guidance for design of future trials., Ann Oncol, 2018. 29 (5)(5): p. 1141-1153., https://pubmed.ncbi.nlm.nih.gov/29788170/

28. Blackwood, HA, Hall, CC, Balstad, TR, Solheim, TS, Fallon, M, Haraldsdottir, E, et.al. A systematic review examining nutrition support interventions in patients with incurable cancer., Support Care Cancer, 2020. 28 (4)(4): p. 1877-1889., https://pubmed.ncbi.nlm.nih.gov/31359182/

29. Dy, SM, Apostol, CC, Evidence-based approaches to other symptoms in advanced cancer., Cancer J, 2010. 16 (5)(5): p. 507-13., https://pubmed.ncbi.nlm.nih.gov/20890148/

30. Del Fabbro, E, Hui, D, Dalal, S, Dev, R, Nooruddin, ZI, Bruera, E, Clinical outcomes and contributors to weight loss in a cancer cachexia clinic., J Palliat Med, 2011. 14 (9)(9): p. 1004-8., https://pubmed.ncbi.nlm.nih.gov/21793729/

31. Clutter Snyder, D, Sloane, R, Haines, PS, Miller, P, Clipp, EC, Morey, MC, et.al. The Diet Quality Index-Revised: a tool to promote and evaluate dietary change among older cancer survivors enrolled in a home-based intervention trial., J Am Diet Assoc, 2007. 107 (9)(9): p. 1519-29., https://pubmed.ncbi.nlm.nih.gov/17761229/

32. Baldwin, C, Spiro, A, Ahern, R, Emery, PW, Oral nutritional interventions in malnourished patients with cancer: a systematic review and meta-analysis., J Natl Cancer Inst, 2012. 104 (5)(5): p. 371-85., https://pubmed.ncbi.nlm.nih.gov/22345712/

33. Bosaeus, I, Nutritional support in multimodal therapy for cancer cachexia., Support Care Cancer, 2008. 16 (5)(5): p. 447-51., https://pubmed.ncbi.nlm.nih.gov/18196284/

34. Odelli, C, Burgess, D, Bateman, L, Hughes, A, Ackland, S, Gillies, J, et.al. Nutrition support improves patient outcomes, treatment tolerance and admission characteristics in oesophageal cancer., Clin Oncol (R Coll Radiol), 2005. 17 (8)(8): p. 639-45., https://pubmed.ncbi.nlm.nih.gov/16372491/

35. Nayel, H, el-Ghoneimy, E, el-Haddad, S, Impact of nutritional supplementation on treatment delay and morbidity in patients with head and neck tumors treated with irradiation., Nutrition, 1992. 8 (1)(1): p. 13-8., https://pubmed.ncbi.nlm.nih.gov/1562782/

36. Paccagnella, A, Morello, M, Da Mosto, MC, Baruffi, C, Marcon, ML, Gava, A, et.al. Early nutritional intervention improves treatment tolerance and outcomes in head and neck cancer patients undergoing concurrent chemoradiotherapy., Support Care Cancer, 2010. 18 (7)(7): p. 837-45., https://pubmed.ncbi.nlm.nih.gov/19727846/

37. Fietkau, R, Iro, H, Sailer, D, Sauer, R, Percutaneous endoscopically guided gastrostomy in patients with head and neck cancer., Recent Results Cancer Res, 1991. 121 (): p. 269-82., https://pubmed.ncbi.nlm.nih.gov/1907019/

38. Tyldesley, S, Sheehan, F, Munk, P, Tsang, V, Skarsgard, D, Bowman, CA, et.al. The use of radiologically placed gastrostomy tubes in head and neck cancer patients receiving radiotherapy., Int J Radiat Oncol Biol Phys, 1996. 36 (5)(5): p. 1205-9., https://pubmed.ncbi.nlm.nih.gov/8985044/

39. Bozzetti, F, Cozzaglio, L, Gavazzi, C, Bidoli, P, Bonfanti, G, Montalto, F, et.al. Nutritional support in patients with cancer of the esophagus: impact on nutritional status, patient compliance to therapy, and survival., Tumori, 1998. 84 (6)(6): p. 681-6., https://pubmed.ncbi.nlm.nih.gov/10080677/

40. Lee, JH, Machtay, M, Unger, LD, Weinstein, GS, Weber, RS, Chalian, AA, et.al. Prophylactic gastrostomy tubes in patients undergoing intensive irradiation for cancer of the head and neck., Arch Otolaryngol Head Neck Surg, 1998. 124 (8)(8): p. 871-5., https://pubmed.ncbi.nlm.nih.gov/9708712/

41. van den Berg, MG, Rasmussen-Conrad, EL, van Nispen, L, van Binsbergen, JJ, Merkx, MA, A prospective study on malnutrition and quality of life in patients with head and neck cancer., Oral Oncol, 2008. 44 (9)(9): p. 830-7., https://pubmed.ncbi.nlm.nih.gov/18243771/

42. Isenring, EA, Bauer, JD, Capra, S, Nutrition support using the American Dietetic Association medical nutrition therapy protocol for radiation oncology patients improves dietary intake compared with standard practice., J Am Diet Assoc, 2007. 107 (3)(3): p. 404-12., https://pubmed.ncbi.nlm.nih.gov/17324657/

43. Marcy, PY, Magné, N, Bensadoun, RJ, Bleuse, A, Falewee, MN, Viot, M, et.al. Systematic percutaneous fluoroscopic gastrostomy for concomitant radiochemotherapy of advanced head and neck cancer: optimization of therapy., Support Care Cancer, 2000. 8 (5)(5): p. 410-3., https://pubmed.ncbi.nlm.nih.gov/10975691/

44. Rabinovitch, R, Grant, B, Berkey, BA, Raben, D, Ang, KK, Fu, KK, et.al. Impact of nutrition support on treatment outcome in patients with locally advanced head and neck squamous cell cancer treated with definitive radiotherapy: a secondary analysis of RTOG trial 90-03., Head Neck, 2006. 28 (4)(4): p. 287-96., https://pubmed.ncbi.nlm.nih.gov/16287132/

45. Leis, C, Arthur, AE, Chen, X, Greene, MW, Frugé, AD, Systematic Review of Nutrition Interventions to Improve Short Term Outcomes in Head and Neck Cancer Patients., Cancers (Basel), 2023. 15 (3)(3):, https://pubmed.ncbi.nlm.nih.gov/36765780/

46. Tunzi, L, Funk, T, Brown, T, Findlay, M, Bauer, J, Optimal frequency of individualised nutrition counselling in patients with head and neck cancer receiving radiotherapy: A systematic review., J Hum Nutr Diet, 2022. 35 (1)(1): p. 223-233., https://pubmed.ncbi.nlm.nih.gov/34003532/

47. Bye, A, Sandmael, JA, Stene, GB, Thorsen, L, Balstad, TR, Solheim, TS, et.al. Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis., Nutrients, 2020. 12 (11)(11):, https://pubmed.ncbi.nlm.nih.gov/33105699/

48. Nugent, B, Lewis, S, O'Sullivan, JM, Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy., Cochrane Database Syst Rev, 2013. 2013 (1)(1): p. CD007904., https://pubmed.ncbi.nlm.nih.gov/23440820/

49. Elia, M, Van Bokhorst-de van der Schueren, MA, Garvey, J, Goedhart, A, Lundholm, K, Nitenberg, G, et.al. Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review., Int J Oncol, 2006. 28 (1)(1): p. 5-23., https://pubmed.ncbi.nlm.nih.gov/16327975/

50. Fietkau, R, Principles of feeding cancer patients via enteral or parenteral nutrition during radiotherapy., Strahlenther Onkol, 1998. 174 Suppl 3 (): p. 47-51., https://pubmed.ncbi.nlm.nih.gov/9830457/

51. Langius, JA, Zandbergen, MC, Eerenstein, SE, van Tulder, MW, Leemans, CR, Kramer, MH, et.al. Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review., Clin Nutr, 2013. 32 (5)(5): p. 671-8., https://pubmed.ncbi.nlm.nih.gov/23845384/

52. Findlay M, Bauer JD, Brown T, Davidson W, Isenring E, Kiss N, Kurmis R, Loeliger J, Sandison A, Talwar B, Taylor K, and the COSA Head and Neck Cancer Nutrition Evidence-Based Guideline Steering Committee, Evidence-based practice guidelines for the nutritional management of adult patients with head and neck cancer, Sydney: Cancer Council Australia, (2011, last updated 2024)., https://www.cancer.org.au/clinical-guidelines/head-neck-cancer

53. Isenring, E., Zabel, R., Bannister, M., Brown, T., Findlay, M., Kiss, N., Loeliger, J., Johnstone, C., Camilleri, B., Davidson, W., Hill, J., & Bauer, J., Updated evidence-based practice guidelines for the nutritional management of patients receiving radiation therapy and/or chemotherapy, Nutrition & Dietetics, 2013. 70(4): p. 312-324., https://doi.org/10.1111/1747-0080.12013

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55. Dempsey, DT, Feurer, ID, Knox, LS, Crosby, LO, Buzby, GP, Mullen, JL, Energy expenditure in malnourished gastrointestinal cancer patients., Cancer, 1984. 53 (6)(6): p. 1265-73., https://pubmed.ncbi.nlm.nih.gov/6692317/

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