14. Literaturverzeichnis – Hautkrebsprävention

1. Hurrelmann, K., Klotz, T., Haisch, J., Krankheitsprävention und GesundheitsförderungHans Huber Verlag, 2010.

2. Faltermaier, Toni, GesundheitspsychologieKohlhammer, 2017. 2, überarbeitete und erweiterte Auflage:

3. Hurrelmann, K., Klotz, T., Haisch, J., Lehrbuch Prävention und GesundheitsförderungHans Huber Verlag, 2009.

4. Hurrelmann, K., Richter, M., Gesundheits¬ und MedizinsoziologieBetlz Juventa, 2013.

5. Graf, C., Starke, D., Nellen, M., Anwendungsorientierung und Qualitätssicherung in der Krankheitsprävention und Gesundheitsförderung, Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2008. 51:1321-1328:

6. Franzkowiak, P., Prävention und Krankheitsprävention, 2018.

7. Rosenbrock, R., Michel, C., Primäre Prävention - Bausteine für eine systematische GesundheitssicherungMedizinisch Wissenschaftliche Verlagsgesellschaft, 2007.

8. Kolenda, K.D., Ratje, U., Mehr Prävention!Hans Marseille Verlag GmbH, 2013.

9. Deutsche Gesellschaft für Nährstoffmedizin und Prävention e.V., Definition der Präventivmedizin, 2015., http://www.dgnp.de/wir-ueber-uns/definition-der-praeventionsmedizin.html

10. Starfield, B., Hyde, J., Gervas, J., Heath, I., The concept of prevention: a good idea gone astray?, J Epidemiol Community Health, 2008. 62(7): p. 580-3., https://www.ncbi.nlm.nih.gov/pubmed/18559439

11. Kühnlein, T., Sghedoni, D., Visentin, G., Gérvas, J., Jamoulle, M.,, Quartäre Prävention, eine Aufgabe für Hausärzte, Primary Care, 2010. 10(18): p. 350-354.

12. Widmer, D., Care and Do Not Harm: Possible Misunderstandings With Quaternary Prevention (P4) Comment on "Quaternary Prevention, an Answer of Family Doctors to Over Medicalization", Int J Health Policy Manag, 2015. 4(8): p. 561-3., https://www.ncbi.nlm.nih.gov/pubmed/26340401

13. Rosenbrock, R., Gerlinger, T., Gesundheitspolitik - Eine systematische Einführung, 2014.

14. Haisch, J., Hurrelmann, K., Klotz, T., Medizinische Prävention und GesundheitsförderungHans Huber Verlag, 2006.

15. Strech, D., Follmann, M., Klemperer, D., Lelgemann, M., Ollenschlager, G., Raspe, H., et.al. When Choosing Wisely meets clinical practice guidelines, Z Evid Fortbild Qual Gesundhwes, 2014. 108(10): p. 601-3., https://www.ncbi.nlm.nih.gov/pubmed/25499114

16. El Ghissassi, F., Baan, R., Straif, K., Grosse, Y., Secretan, B., Bouvard, V., et.al. A review of human carcinogens--part D: radiation, Lancet Oncol, 2009. 10(8): p. 751-2.

17. International Commission on Non-Ionizing Radiation Protection (ICNIRP), Proceedings Third International Non-Ionizing Radiation Workshop, Baden, Austria. R. Matthes (ed.), 1996.

18. Ridley, A. J., Whiteside, J. R., McMillan, T. J., Allinson, S. L., Cellular and sub-cellular responses to UVA in relation to carcinogenesis, Int J Radiat Biol, 2009. 85(3): p. 177-95., https://www.ncbi.nlm.nih.gov/pubmed/19296341

19. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, IARC monographs on the evaluation of carcinogenic risks to humans. A review of human carcinogens: Radiation, 2012. 100D:

20. Ikehata, H., Ono, T., The mechanisms of UV mutagenesis, J Radiat Res, 2011. 52(2): p. 115-25., https://www.ncbi.nlm.nih.gov/pubmed/21436607

21. Cadet, J., Douki, T., Ravanat, J. L., Oxidatively generated base damage to cellular DNA, Free Radic Biol Med, 2010. 49(1): p. 9-21., https://www.ncbi.nlm.nih.gov/pubmed/20363317

22. Courdavault, S., Baudouin, C., Charveron, M., Favier, A., Cadet, J., Douki, T., Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells, Mutat Res, 2004. 556(1-2): p. 135-42., https://www.ncbi.nlm.nih.gov/pubmed/15491641

23. Douki, T., Reynaud-Angelin, A., Cadet, J., Sage, E., Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation, Biochemistry, 2003. 42(30): p. 9221-6., https://www.ncbi.nlm.nih.gov/pubmed/12885257

24. Mouret, S., Baudouin, C., Charveron, M., Favier, A., Cadet, J., Douki, T., Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation, Proc Natl Acad Sci U S A, 2006. 103(37): p. 13765-70., https://www.ncbi.nlm.nih.gov/pubmed/16954188

25. Mouret, S., Forestier, A., Douki, T., The specificity of UVA-induced DNA damage in human melanocytes, Photochem Photobiol Sci, 2012. 11(1): p. 155-62., https://www.ncbi.nlm.nih.gov/pubmed/21986862

26. Kozmin, S. G., Pavlov, Y. I., Kunkel, T. A., Sage, E., Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight, Nucleic Acids Res, 2003. 31(15): p. 4541-52., https://www.ncbi.nlm.nih.gov/pubmed/12888515

27. Pfeifer, G. P., Besaratinia, A., UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer, Photochem Photobiol Sci, 2012. 11(1): p. 90-7.

28. Cannistraro, V. J., Taylor, J. S., Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots, J Mol Biol, 2009. 392(5): p. 1145-57., https://www.ncbi.nlm.nih.gov/pubmed/19631218

29. Hendriks, G., Jansen, J. G., Mullenders, L. H., de Wind, N., Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light, Transcription, 2010. 1(2): p. 95-8., https://www.ncbi.nlm.nih.gov/pubmed/21326899

30. Pfeifer, G. P., Besaratinia, A., UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer, Photochem Photobiol Sci, 2012. 11(1): p. 90-7., https://www.ncbi.nlm.nih.gov/pubmed/21804977

31. Tu, Y., Dammann, R., Pfeifer, G. P., Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo, J Mol Biol, 1998. 284(2): p. 297-311., https://www.ncbi.nlm.nih.gov/pubmed/9813119

32. Pleasance, E. D., Cheetham, R. K., Stephens, P. J., McBride, D. J., Humphray, S. J., Greenman, C. D., et.al. A comprehensive catalogue of somatic mutations from a human cancer genome, Nature, 2010. 463(7278): p. 191-6., https://www.ncbi.nlm.nih.gov/pubmed/20016485

33. Armstrong, B. K., Kricker, A., The epidemiology of UV induced skin cancer, J Photochem Photobiol B, 2001. 63(1-3): p. 8-18., https://www.ncbi.nlm.nih.gov/pubmed/11684447

34. Gallagher, R. P., Hill, G. B., Bajdik, C. D., Fincham, S., Coldman, A. J., McLean, D. I., et.al. Sunlight exposure, pigmentary factors, and risk of nonmelanocytic skin cancer. I. Basal cell carcinoma, Arch Dermatol, 1995. 131(2): p. 157-63.

35. Kricker, A., Armstrong, B. K., English, D. R., Heenan, P. J., Pigmentary and cutaneous risk factors for non-melanocytic skin cancer--a case-control study, Int J Cancer, 1991. 48(5): p. 650-62., https://www.ncbi.nlm.nih.gov/pubmed/2071226

36. Kricker, A., Armstrong, B. K., English, D. R., Heenan, P. J., Does intermittent sun exposure cause basal cell carcinoma? a case-control study in Western Australia, Int J Cancer, 1995. 60(4): p. 489-94., https://www.ncbi.nlm.nih.gov/pubmed/7829262

37. Kricker, A., Armstrong, B. K., English, D. R., Heenan, P. J., A dose-response curve for sun exposure and basal cell carcinoma, Int J Cancer, 1995. 60(4): p. 482-8., https://www.ncbi.nlm.nih.gov/pubmed/7829261

38. Rosso, S., Zanetti, R., Martinez, C., Tormo, M. J., Schraub, S., Sancho-Garnier, H., et.al. The multicentre south European study 'Helios'. II: Different sun exposure patterns in the aetiology of basal cell and squamous cell carcinomas of the skin, Br J Cancer, 1996. 73(11): p. 1447-54., https://www.ncbi.nlm.nih.gov/pubmed/8645596

39. Vitasa, B. C., Taylor, H. R., Strickland, P. T., Rosenthal, F. S., West, S., Abbey, H., et.al. Association of nonmelanoma skin cancer and actinic keratosis with cumulative solar ultraviolet exposure in Maryland watermen, Cancer, 1990. 65(12): p. 2811-7., https://www.ncbi.nlm.nih.gov/pubmed/2340474

40. Zanetti, R., Rosso, S., Martinez, C., Navarro, C., Schraub, S., Sancho-Garnier, H., et.al. The multicentre south European study 'Helios'. I: Skin characteristics and sunburns in basal cell and squamous cell carcinomas of the skin, Br J Cancer, 1996. 73(11): p. 1440-6., https://www.ncbi.nlm.nih.gov/pubmed/8645595

41. Kimonis, V. E., Goldstein, A. M., Pastakia, B., Yang, M. L., Kase, R., DiGiovanna, J. J., et.al. Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome, Am J Med Genet, 1997. 69(3): p. 299-308., https://www.ncbi.nlm.nih.gov/pubmed/9096761

42. Shanley, S., Ratcliffe, J., Hockey, A., Haan, E., Oley, C., Ravine, D., et.al. Nevoid basal cell carcinoma syndrome: review of 118 affected individuals, Am J Med Genet, 1994. 50(3): p. 282-90., https://www.ncbi.nlm.nih.gov/pubmed/8042673

43. Hahn, H., Wicking, C., Zaphiropoulous, P. G., Gailani, M. R., Shanley, S., Chidambaram, A., et.al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome, Cell, 1996. 85(6): p. 841-51., https://www.ncbi.nlm.nih.gov/pubmed/8681379

44. Johnson, R. L., Rothman, A. L., Xie, J., Goodrich, L. V., Bare, J. W., Bonifas, J. M., et.al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome, Science, 1996. 272(5268): p. 1668-71., https://www.ncbi.nlm.nih.gov/pubmed/8658145

45. Stone, D. M., Hynes, M., Armanini, M., Swanson, T. A., Gu, Q., Johnson, R. L., et.al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog, Nature, 1996. 384(6605): p. 129-34., https://www.ncbi.nlm.nih.gov/pubmed/8906787

46. Brellier, F., Marionnet, C., Chevallier-Lagente, O., Toftgard, R., Mauviel, A., Sarasin, A., et.al. Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process, Cancer Res, 2004. 64(8): p. 2699-704., https://www.ncbi.nlm.nih.gov/pubmed/15087382

47. Fan, H., Khavari, P. A., Sonic hedgehog opposes epithelial cell cycle arrest, J Cell Biol, 1999. 147(1): p. 71-6., https://www.ncbi.nlm.nih.gov/pubmed/10508856

48. Aszterbaum, M., Beech, J., Epstein, E. H., Jr., Ultraviolet radiation mutagenesis of hedgehog pathway genes in basal cell carcinomas, J Investig Dermatol Symp Proc, 1999. 4(1): p. 41-5., https://www.ncbi.nlm.nih.gov/pubmed/10537006

49. Grachtchouk, M., Mo, R., Yu, S., Zhang, X., Sasaki, H., Hui, C. C., et.al. Basal cell carcinomas in mice overexpressing Gli2 in skin, Nat Genet, 2000. 24(3): p. 216-7., https://www.ncbi.nlm.nih.gov/pubmed/10700170

50. Nilsson, M., Unden, A. B., Krause, D., Malmqwist, U., Raza, K., Zaphiropoulos, P. G., et.al. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1, Proc Natl Acad Sci U S A, 2000. 97(7): p. 3438-43., https://www.ncbi.nlm.nih.gov/pubmed/10725363

51. Oro, A. E., Higgins, K. M., Hu, Z., Bonifas, J. M., Epstein, E. H., Jr., Scott, M. P., Basal cell carcinomas in mice overexpressing sonic hedgehog, Science, 1997. 276(5313): p. 817-21., https://www.ncbi.nlm.nih.gov/pubmed/9115210

52. Grachtchouk, M., Pero, J., Yang, S. H., Ermilov, A. N., Michael, L. E., Wang, A., et.al. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations, J Clin Invest, 2011. 121(5): p. 1768-81., https://www.ncbi.nlm.nih.gov/pubmed/21519145

53. Wang, G. Y., Wang, J., Mancianti, M. L., Epstein, E. H., Jr., Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice, Cancer Cell, 2011. 19(1): p. 114-24., https://www.ncbi.nlm.nih.gov/pubmed/21215705

54. Gailani, M. R., Stahle-Backdahl, M., Leffell, D. J., Glynn, M., Zaphiropoulos, P. G., Pressman, C., et.al. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas, Nat Genet, 1996. 14(1): p. 78-81., https://www.ncbi.nlm.nih.gov/pubmed/8782823

55. Lupi, O., Correlations between the Sonic Hedgehog pathway and basal cell carcinoma, Int J Dermatol, 2007. 46(11): p. 1113-7., https://www.ncbi.nlm.nih.gov/pubmed/17988327

56. Reifenberger, J., Wolter, M., Knobbe, C. B., Kohler, B., Schonicke, A., Scharwachter, C., et.al. Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas, Br J Dermatol, 2005. 152(1): p. 43-51., https://www.ncbi.nlm.nih.gov/pubmed/15656799

57. Xie, J., Murone, M., Luoh, S. M., Ryan, A., Gu, Q., Zhang, C., et.al. Activating Smoothened mutations in sporadic basal-cell carcinoma, Nature, 1998. 391(6662): p. 90-2., https://www.ncbi.nlm.nih.gov/pubmed/9422511

58. Bakshi, A., Chaudhary, S. C., Rana, M., Elmets, C. A., Athar, M., Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond, Mol Carcinog, 2017. 56(12): p. 2543-2557., https://www.ncbi.nlm.nih.gov/pubmed/28574612

59. Aszterbaum, M., Epstein, J., Oro, A., Douglas, V., LeBoit, P. E., Scott, M. P., et.al. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice, Nat Med, 1999. 5(11): p. 1285-91., https://www.ncbi.nlm.nih.gov/pubmed/10545995

60. Couve-Privat, S., Bouadjar, B., Avril, M. F., Sarasin, A., Daya-Grosjean, L., Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients, Cancer Res, 2002. 62(24): p. 7186-9., https://www.ncbi.nlm.nih.gov/pubmed/12499255

61. Couve-Privat, S., Le Bret, M., Traiffort, E., Queille, S., Coulombe, J., Bouadjar, B., et.al. Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients, Cancer Res, 2004. 64(10): p. 3559-65., https://www.ncbi.nlm.nih.gov/pubmed/15150112

62. Daya-Grosjean, L., Couve-Privat, S., Sonic hedgehog signaling in basal cell carcinomas, Cancer Lett, 2005. 225(2): p. 181-92., https://www.ncbi.nlm.nih.gov/pubmed/15978322

63. Daya-Grosjean, L., Sarasin, A., UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients, Mutat Res, 2000. 450(1-2): p. 193-9., https://www.ncbi.nlm.nih.gov/pubmed/10838143

64. Evans, T., Boonchai, W., Shanley, S., Smyth, I., Gillies, S., Georgas, K., et.al. The spectrum of patched mutations in a collection of Australian basal cell carcinomas, Hum Mutat, 2000. 16(1): p. 43-8., https://www.ncbi.nlm.nih.gov/pubmed/10874304

65. Kim, M. Y., Park, H. J., Baek, S. C., Byun, D. G., Houh, D., Mutations of the p53 and PTCH gene in basal cell carcinomas: UV mutation signature and strand bias, J Dermatol Sci, 2002. 29(1): p. 1-9., https://www.ncbi.nlm.nih.gov/pubmed/12007715

66. Ratner, D., Peacocke, M., Zhang, H., Ping, X. L., Tsou, H. C., UV-specific p53 and PTCH mutations in sporadic basal cell carcinoma of sun-exposed skin, J Am Acad Dermatol, 2001. 44(2): p. 293-7., https://www.ncbi.nlm.nih.gov/pubmed/11174390

67. Bolshakov, S., Walker, C. M., Strom, S. S., Selvan, M. S., Clayman, G. L., El-Naggar, A., et.al. p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas, Clin Cancer Res, 2003. 9(1): p. 228-34., https://www.ncbi.nlm.nih.gov/pubmed/12538474

68. Boehnke, K., Falkowska-Hansen, B., Stark, H. J., Boukamp, P., Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis, Carcinogenesis, 2012. 33(7): p. 1247-58., https://www.ncbi.nlm.nih.gov/pubmed/22461521

69. Jin, Y., Mertens, F., Persson, B., Warloe, T., Gullestad, H. P., Salemark, L., et.al. Nonrandom numerical chromosome abnormalities in basal cell carcinomas, Cancer Genet Cytogenet, 1998. 103(1): p. 35-42., https://www.ncbi.nlm.nih.gov/pubmed/9595042

70. Jin, Y., Martins, C., Salemark, L., Persson, B., Jin, C., Miranda, J., et.al. Nonrandom karyotypic features in basal cell carcinomas of the skin, Cancer Genet Cytogenet, 2001. 131(2): p. 109-19., https://www.ncbi.nlm.nih.gov/pubmed/11750050

71. Karagas, M. R., Zens, M. S., Nelson, H. H., Mabuchi, K., Perry, A. E., Stukel, T. A., et.al. Measures of cumulative exposure from a standardized sun exposure history questionnaire: a comparison with histologic assessment of solar skin damage, Am J Epidemiol, 2007. 165(6): p. 719-26., https://www.ncbi.nlm.nih.gov/pubmed/17204514

72. Kennedy, C., Bajdik, C. D., Willemze, R., De Gruijl, F. R., Bouwes Bavinck, J. N., Leiden Skin Cancer, Study, The influence of painful sunburns and lifetime sun exposure on the risk of actinic keratoses, seborrheic warts, melanocytic nevi, atypical nevi, and skin cancer, J Invest Dermatol, 2003. 120(6): p. 1087-93., https://www.ncbi.nlm.nih.gov/pubmed/12787139

73. Salasche, S. J., Epidemiology of actinic keratoses and squamous cell carcinoma, J Am Acad Dermatol, 2000. 42(1 Pt 2): p. 4-7., https://www.ncbi.nlm.nih.gov/pubmed/10607349

74. Dodson, J. M., DeSpain, J., Hewett, J. E., Clark, D. P., Malignant potential of actinic keratoses and the controversy over treatment. A patient-oriented perspective, Arch Dermatol, 1991. 127(7): p. 1029-31., https://www.ncbi.nlm.nih.gov/pubmed/2064402

75. Glogau, R. G., The risk of progression to invasive disease, J Am Acad Dermatol, 2000. 42(1 Pt 2): p. 23-4., https://www.ncbi.nlm.nih.gov/pubmed/10607353

76. Marks, R., Rennie, G., Selwood, T., The relationship of basal cell carcinomas and squamous cell carcinomas to solar keratoses, Arch Dermatol, 1988. 124(7): p. 1039-42., https://www.ncbi.nlm.nih.gov/pubmed/3389848

77. Marks, R., Rennie, G., Selwood, T. S., Malignant transformation of solar keratoses to squamous cell carcinoma, Lancet, 1988. 1(8589): p. 795-7., https://www.ncbi.nlm.nih.gov/pubmed/2895318

78. Czarnecki, D., Meehan, C. J., Bruce, F., Culjak, G., The majority of cutaneous squamous cell carcinomas arise in actinic keratoses, J Cutan Med Surg, 2002. 6(3): p. 207-9., https://www.ncbi.nlm.nih.gov/pubmed/11951126

79. Criscione, V. D., Weinstock, M. A., Naylor, M. F., Luque, C., Eide, M. J., Bingham, S. F., et.al. Actinic keratoses: Natural history and risk of malignant transformation in the Veterans Affairs Topical Tretinoin Chemoprevention Trial, Cancer, 2009. 115(11): p. 2523-30., https://www.ncbi.nlm.nih.gov/pubmed/19382202

80. Chen, G. J., Feldman, S. R., Williford, P. M., Hester, E. J., Kiang, S. H., Gill, I., et.al. Clinical diagnosis of actinic keratosis identifies an elderly population at high risk of developing skin cancer, Dermatol Surg, 2005. 31(1): p. 43-7., https://www.ncbi.nlm.nih.gov/pubmed/15720095

81. Feldman, S. R., Fleischer, A. B., Jr., Progression of actinic keratosis to squamous cell carcinoma revisited: clinical and treatment implications, Cutis, 2011. 87(4): p. 201-7., https://www.ncbi.nlm.nih.gov/pubmed/21644496

82. Quaedvlieg, P. J., Tirsi, E., Thissen, M. R., Krekels, G. A., Actinic keratosis: how to differentiate the good from the bad ones?, Eur J Dermatol, 2006. 16(4): p. 335-9., https://www.ncbi.nlm.nih.gov/pubmed/16935787

83. Kanellou, P., Zaravinos, A., Zioga, M., Stratigos, A., Baritaki, S., Soufla, G., et.al. Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis, Cancer Lett, 2008. 264(1): p. 145-61., https://www.ncbi.nlm.nih.gov/pubmed/18331779

84. Padilla, R. S., Sebastian, S., Jiang, Z., Nindl, I., Larson, R., Gene expression patterns of normal human skin, actinic keratosis, and squamous cell carcinoma: a spectrum of disease progression, Arch Dermatol, 2010. 146(3): p. 288-93., https://www.ncbi.nlm.nih.gov/pubmed/20231500

85. Drake, L. A., Ceilley, R. I., Cornelison, R. L., Dobes, W. L., Dorner, W., Goltz, R. W., et.al. Guidelines of care for actinic keratoses. Committee on Guidelines of Care, J Am Acad Dermatol, 1995. 32(1): p. 95-8., https://www.ncbi.nlm.nih.gov/pubmed/7529779

86. Lober, B. A., Lober, C. W., Actinic keratosis is squamous cell carcinoma, South Med J, 2000. 93(7): p. 650-5., https://www.ncbi.nlm.nih.gov/pubmed/10923948

87. Stulberg, D. L., Crandell, B., Fawcett, R. S., Diagnosis and treatment of basal cell and squamous cell carcinomas, Am Fam Physician, 2004. 70(8): p. 1481-8., https://www.ncbi.nlm.nih.gov/pubmed/15526735

88. Ackerman, A. B., Mones, J. M., Solar (actinic) keratosis is squamous cell carcinoma, Br J Dermatol, 2006. 155(1): p. 9-22., https://www.ncbi.nlm.nih.gov/pubmed/16792746

89. Anwar, J., Wrone, D. A., Kimyai-Asadi, A., Alam, M., The development of actinic keratosis into invasive squamous cell carcinoma: evidence and evolving classification schemes, Clin Dermatol, 2004. 22(3): p. 189-96., https://www.ncbi.nlm.nih.gov/pubmed/15262304

90. Cockerell, C. J., Histopathology of incipient intraepidermal squamous cell carcinoma ('actinic keratosis'), Journal of the American Academy of Dermatology, 2000. p. 42(1 II)(pp S11-S17), 2000., https://www.ncbi.nlm.nih.gov/pubmed/10607351

91. Roewert-Huber, J., Stockfleth, E., Kerl, H., Pathology and pathobiology of actinic (solar) keratosis - an update, Br J Dermatol, 2007. 157 Suppl 2: p. 18-20., https://www.ncbi.nlm.nih.gov/pubmed/18067626

92. Fernandez-Figueras, M. T., Carrato, C., Saenz, X., Puig, L., Musulen, E., Ferrandiz, C., et.al. Actinic keratosis with atypical basal cells (AK I) is the most common lesion associated with invasive squamous cell carcinoma of the skin, J Eur Acad Dermatol Venereol, 2015. 29(5): p. 991-7., https://www.ncbi.nlm.nih.gov/pubmed/25428612

93. Brash, D. E., Sunlight and the onset of skin cancer, Trends Genet, 1997. 13(10): p. 410-4., https://www.ncbi.nlm.nih.gov/pubmed/9351343

94. Cleaver, J. E., Crowley, E., UV damage, DNA repair and skin carcinogenesis, Front Biosci, 2002. 7: p. d1024-43., https://www.ncbi.nlm.nih.gov/pubmed/11897551

95. Ziegler, A., Jonason, A. S., Leffell, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., et.al. Sunburn and p53 in the onset of skin cancer, Nature, 1994. 372(6508): p. 773-6., https://www.ncbi.nlm.nih.gov/pubmed/7997263

96. Park, W. S., Lee, H. K., Lee, J. Y., Yoo, N. J., Kim, C. S., Kim, S. H., p53 mutations in solar keratoses, Hum Pathol, 1996. 27(11): p. 1180-4., https://www.ncbi.nlm.nih.gov/pubmed/8912828

97. Ortonne, J. P., From actinic keratosis to squamous cell carcinoma, Br J Dermatol, 2002. 146 Suppl 61: p. 20-3., https://www.ncbi.nlm.nih.gov/pubmed/11966728

98. Mitchell, D. L., The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells, Photochem Photobiol, 1988. 48(1): p. 51-7., https://www.ncbi.nlm.nih.gov/pubmed/3217442

99. Greinert, R., Boguhn, O., Harder, D., Breitbart, E. W., Mitchell, D. L., Volkmer, B., The dose dependence of cyclobutane dimer induction and repair in UVB-irradiated human keratinocytes, Photochem Photobiol, 2000. 72(5): p. 701-8., https://www.ncbi.nlm.nih.gov/pubmed/11107858

100. Kielbassa, C., Roza, L., Epe, B., Wavelength dependence of oxidative DNA damage induced by UV and visible light, Carcinogenesis, 1997. 18(4): p. 811-6., https://www.ncbi.nlm.nih.gov/pubmed/9111219

101. Perdiz, D., Grof, P., Mezzina, M., Nikaido, O., Moustacchi, E., Sage, E., Distribution and repair of bipyrimidine photoproducts in solar UV-irradiated mammalian cells. Possible role of Dewar photoproducts in solar mutagenesis, J Biol Chem, 2000. 275(35): p. 26732-42., https://www.ncbi.nlm.nih.gov/pubmed/10827179

102. Rochette, P. J., Therrien, J. P., Drouin, R., Perdiz, D., Bastien, N., Drobetsky, E. A., et.al. UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells, Nucleic Acids Res, 2003. 31(11): p. 2786-94., https://www.ncbi.nlm.nih.gov/pubmed/12771205

103. Tornaletti, S., Pfeifer, G. P., Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer, Science, 1994. 263(5152): p. 1436-8., https://www.ncbi.nlm.nih.gov/pubmed/8128225

104. Tornaletti, S., Rozek, D., Pfeifer, G. P., The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer, Oncogene, 1993. 8(8): p. 2051-7., https://www.ncbi.nlm.nih.gov/pubmed/8336934

105. Berg, R. J., van Kranen, H. J., Rebel, H. G., de Vries, A., van Vloten, W. A., Van Kreijl, C. F., et.al. Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells, Proc Natl Acad Sci U S A, 1996. 93(1): p. 274-8., https://www.ncbi.nlm.nih.gov/pubmed/8552621

106. Luo, J. L., Tong, W. M., Yoon, J. H., Hergenhahn, M., Koomagi, R., Yang, Q., et.al. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin, Cancer Res, 2001. 61(22): p. 8158-63., https://www.ncbi.nlm.nih.gov/pubmed/11719445

107. Mitchell, D. L., Byrom, M., Chiarello, S., Lowery, M. G., Effects of chronic exposure to ultraviolet B radiation on DNA repair in the dermis and epidermis of the hairless mouse, J Invest Dermatol, 2001. 116(2): p. 209-15., https://www.ncbi.nlm.nih.gov/pubmed/11179995

108. Mitchell, D. L., Volkmer, B., Breitbart, E. W., Byrom, M., Lowery, M. G., Greinert, R., Identification of a non-dividing subpopulation of mouse and human epidermal cells exhibiting high levels of persistent ultraviolet photodamage, J Invest Dermatol, 2001. 117(3): p. 590-5., https://www.ncbi.nlm.nih.gov/pubmed/11564164

109. Gambardella, L., Barrandon, Y., The multifaceted adult epidermal stem cell, Curr Opin Cell Biol, 2003. 15(6): p. 771-7., https://www.ncbi.nlm.nih.gov/pubmed/14644204

110. Bickenbach, J. R., Holbrook, K. A., Label-retaining cells in human embryonic and fetal epidermis, J Invest Dermatol, 1987. 88(1): p. 42-6., https://www.ncbi.nlm.nih.gov/pubmed/3794386

111. Braun, K. M., Watt, F. M., Epidermal label-retaining cells: background and recent applications, J Investig Dermatol Symp Proc, 2004. 9(3): p. 196-201., https://www.ncbi.nlm.nih.gov/pubmed/15369213

112. Cairns, J., Mutation selection and the natural history of cancer, Nature, 1975. 255(5505): p. 197-200., https://www.ncbi.nlm.nih.gov/pubmed/1143315

113. Cairns, J., Somatic stem cells and the kinetics of mutagenesis and carcinogenesis, Proc Natl Acad Sci U S A, 2002. 99(16): p. 10567-70., https://www.ncbi.nlm.nih.gov/pubmed/12149477

114. Potten, C. S., Owen, G., Booth, D., Intestinal stem cells protect their genome by selective segregation of template DNA strands, J Cell Sci, 2002. 115(Pt 11): p. 2381-8., https://www.ncbi.nlm.nih.gov/pubmed/12006622

115. Boukamp, P., Non-melanoma skin cancer: what drives tumor development and progression?, Carcinogenesis, 2005. 26(10): p. 1657-67., https://www.ncbi.nlm.nih.gov/pubmed/15905207

116. Quinn, A. G., Sikkink, S., Rees, J. L., Delineation of two distinct deleted regions on chromosome 9 in human non-melanoma skin cancers, Genes Chromosomes Cancer, 1994. 11(4): p. 222-5., https://www.ncbi.nlm.nih.gov/pubmed/7533525

117. Rehman, I., Takata, M., Wu, Y. Y., Rees, J. L., Genetic change in actinic keratoses, Oncogene, 1996. 12(12): p. 2483-90., https://www.ncbi.nlm.nih.gov/pubmed/8700506

118. Popp, S., Waltering, S., Herbst, C., Moll, I., Boukamp, P., UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas, Int J Cancer, 2002. 99(3): p. 352-60., https://www.ncbi.nlm.nih.gov/pubmed/11992403

119. Greinert, R., Volkmer, B., Henning, S., Breitbart, E. W., Greulich, K. O., Cardoso, M. C., et.al. UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages, Nucleic Acids Res, 2012. 40(20): p. 10263-73., https://www.ncbi.nlm.nih.gov/pubmed/22941639

120. Rapp, A., Greulich, K. O., After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available, J Cell Sci, 2004. 117(Pt 21): p. 4935-45., https://www.ncbi.nlm.nih.gov/pubmed/15367581

121. Armstrong, B. K., Kricker, A., The epidemiology of UV induced skin cancer, J Photochem Photobiol B, 2001. 63(1-3): p. 8-18., https://www.ncbi.nlm.nih.gov/pubmed/11684447

122. Dulon, M., Weichenthal, M., Blettner, M., Breitbart, M., Hetzer, M., Greinert, R., et.al. Sun exposure and number of nevi in 5- to 6-year-old European children, J Clin Epidemiol, 2002. 55(11): p. 1075-81., https://www.ncbi.nlm.nih.gov/pubmed/12507670

123. Gruis, N. A., van Doorn, R., Melanocortin 1 receptor function: shifting gears from determining skin and nevus phenotype to fetal growth, J Invest Dermatol, 2012. 132(8): p. 1953-5., https://www.ncbi.nlm.nih.gov/pubmed/22797298

124. Schaffer, J. V., Bolognia, J. L., The melanocortin-1 receptor: red hair and beyond, Arch Dermatol, 2001. 137(11): p. 1477-85., https://www.ncbi.nlm.nih.gov/pubmed/11708951

125. Robinson, S., Dixon, S., August, S., Diffey, B., Wakamatsu, K., Ito, S., et.al. Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo, J Invest Dermatol, 2010. 130(7): p. 1904-13., https://www.ncbi.nlm.nih.gov/pubmed/20237490

126. Barnhill, R. L., Roush, G. C., Titus-Ernstoff, L., Ernstoff, M. S., Duray, P. H., Kirkwood, J. M., Comparison of nonfamilial and familial melanoma, Dermatology, 1992. 184(1): p. 2-7., https://www.ncbi.nlm.nih.gov/pubmed/1558990

127. Fountain, J. W., Bale, S. J., Housman, D. E., Dracopoli, N. C., Genetics of melanoma, Cancer Surv, 1990. 9(4): p. 645-71., https://www.ncbi.nlm.nih.gov/pubmed/2101727

128. Hansson, J., Familial cutaneous melanoma, Adv Exp Med Biol, 2010. 685(Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital Solna S-171 76, Stockholm, Sweden. johan.hansson@ki.se): p. 134-45., https://www.ncbi.nlm.nih.gov/pubmed/20687502

129. Markovic, S. N., Erickson, L. A., Rao, R. D., Weenig, R. H., Pockaj, B. A., Bardia, A., et.al. Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis, Mayo Clin Proc, 2007. 82(3): p. 364-80., https://www.ncbi.nlm.nih.gov/pubmed/17352373

130. Psaty, E. L., Scope, A., Halpern, A. C., Marghoob, A. A., Defining the patient at high risk for melanoma, Int J Dermatol, 2010. 49(4): p. 362-76., https://www.ncbi.nlm.nih.gov/pubmed/20465687

131. Hussussian, C. J., Struewing, J. P., Goldstein, A. M., Higgins, P. A., Ally, D. S., Sheahan, M. D., et.al. Germline p16 mutations in familial melanoma, Nat Genet, 1994. 8(1): p. 15-21., https://www.ncbi.nlm.nih.gov/pubmed/7987387

132. Kamb, A., Shattuck-Eidens, D., Eeles, R., Liu, Q., Gruis, N. A., Ding, W., et.al. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus, Nat Genet, 1994. 8(1): p. 23-6., https://www.ncbi.nlm.nih.gov/pubmed/7987388

133. Udayakumar, D., Mahato, B., Gabree, M., Tsao, H., Genetic determinants of cutaneous melanoma predisposition, Semin Cutan Med Surg, 2010. 29(3): p. 190-5., https://www.ncbi.nlm.nih.gov/pubmed/21051013

134. Chin, L., The genetics of malignant melanoma: lessons from mouse and man, Nat Rev Cancer, 2003. 3(8): p. 559-70., https://www.ncbi.nlm.nih.gov/pubmed/12894244

135. Sherr, C. J., The INK4a/ARF network in tumour suppression, Nat Rev Mol Cell Biol, 2001. 2(10): p. 731-7., https://www.ncbi.nlm.nih.gov/pubmed/11584300

136. Ha, L., Ichikawa, T., Anver, M., Dickins, R., Lowe, S., Sharpless, N. E., et.al. ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence, Proc Natl Acad Sci U S A, 2007. 104(26): p. 10968-73., https://www.ncbi.nlm.nih.gov/pubmed/17576930

137. Piccinin, S., Doglioni, C., Maestro, R., Vukosavljevic, T., Gasparotto, D., D'Orazi, C., et.al. p16/CDKN2 and CDK4 gene mutations in sporadic melanoma development and progression, Int J Cancer, 1997. 74(1): p. 26-30., https://www.ncbi.nlm.nih.gov/pubmed/9036865

138. Garcia-Casado, Z., Nagore, E., Fernandez-Serra, A., Botella-Estrada, R., Lopez-Guerrero, J. A., A germline mutation of p14/ARF in a melanoma kindred, Melanoma Res, 2009. 19(5): p. 335-7., https://www.ncbi.nlm.nih.gov/pubmed/19741424

139. Randerson-Moor, J. A., Harland, M., Williams, S., Cuthbert-Heavens, D., Sheridan, E., Aveyard, J., et.al. A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family, Hum Mol Genet, 2001. 10(1): p. 55-62., https://www.ncbi.nlm.nih.gov/pubmed/11136714

140. Daniotti, M., Oggionni, M., Ranzani, T., Vallacchi, V., Campi, V., Di Stasi, D., et.al. BRAF alterations are associated with complex mutational profiles in malignant melanoma, Oncogene, 2004. 23(35): p. 5968-77., https://www.ncbi.nlm.nih.gov/pubmed/15195137

141. Daniotti, M., Vallacchi, V., Rivoltini, L., Patuzzo, R., Santinami, M., Arienti, F., et.al. Detection of mutated BRAFV600E variant in circulating DNA of stage III-IV melanoma patients, Int J Cancer, 2007. 120(11): p. 2439-44., https://www.ncbi.nlm.nih.gov/pubmed/17315191

142. Hodis, E., Watson, I. R., Kryukov, G. V., Arold, S. T., Imielinski, M., Theurillat, J. P., et.al. A landscape of driver mutations in melanoma, Cell, 2012. 150(2): p. 251-63., https://www.ncbi.nlm.nih.gov/pubmed/22817889

143. Mann, G. J., Pupo, G. M., Campain, A. E., Carter, C. D., Schramm, S. J., Pianova, S., et.al. BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma, J Invest Dermatol, 2012., https://www.ncbi.nlm.nih.gov/pubmed/22931913

144. Sasaki, Y., Niu, C., Makino, R., Kudo, C., Sun, C., Watanabe, H., et.al. BRAF point mutations in primary melanoma show different prevalences by subtype, J Invest Dermatol, 2004. 123(1): p. 177-83., https://www.ncbi.nlm.nih.gov/pubmed/15191558

145. Sosman, J. A., Kim, K. B., Schuchter, L., Gonzalez, R., Pavlick, A. C., Weber, J. S., et.al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib, N Engl J Med, 2012. 366(8): p. 707-14., https://www.ncbi.nlm.nih.gov/pubmed/22356324

146. Hayward, N., New developments in melanoma genetics, Curr Oncol Rep, 2000. 2(4): p. 300-6., https://www.ncbi.nlm.nih.gov/pubmed/11122857

147. Kvaskoff, M., Whiteman, D. C., Zhao, Z. Z., Montgomery, G. W., Martin, N. G., Hayward, N. K., et.al. Polymorphisms in nevus-associated genes MTAP, PLA2G6, and IRF4 and the risk of invasive cutaneous melanoma, Twin Res Hum Genet, 2011. 14(5): p. 422-32., https://www.ncbi.nlm.nih.gov/pubmed/21962134

148. Whiteman, D. C., Watt, P., Purdie, D. M., Hughes, M. C., Hayward, N. K., Green, A. C., Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma, J Natl Cancer Inst, 2003. 95(11): p. 806-12., https://www.ncbi.nlm.nih.gov/pubmed/12783935

149. Bennett, D. C., Human melanocyte senescence and melanoma susceptibility genes, Oncogene, 2003. 22(20): p. 3063-9., https://www.ncbi.nlm.nih.gov/pubmed/12789281

150. Gray-Schopfer, V. C., Cheong, S. C., Chong, H., Chow, J., Moss, T., Abdel-Malek, Z. A., et.al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16?, Br J Cancer, 2006. 95(4): p. 496-505., https://www.ncbi.nlm.nih.gov/pubmed/16880792

151. Haferkamp, S., Becker, T. M., Scurr, L. L., Kefford, R. F., Rizos, H., p16INK4a-induced senescence is disabled by melanoma-associated mutations, Aging Cell, 2008. 7(5): p. 733-45., https://www.ncbi.nlm.nih.gov/pubmed/18843795

152. Demunter, A., Ahmadian, M. R., Libbrecht, L., Stas, M., Baens, M., Scheffzek, K., et.al. A novel N-ras mutation in malignant melanoma is associated with excellent prognosis, Cancer Res, 2001. 61(12): p. 4916-22., https://www.ncbi.nlm.nih.gov/pubmed/11406571

153. Demunter, A., Stas, M., Degreef, H., De Wolf-Peeters, C., van den Oord, J. J., Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma, J Invest Dermatol, 2001. 117(6): p. 1483-9., https://www.ncbi.nlm.nih.gov/pubmed/11886512

154. Eskandarpour, M., Huang, F., Reeves, K. A., Clark, E., Hansson, J., Oncogenic NRAS has multiple effects on the malignant phenotype of human melanoma cells cultured in vitro, Int J Cancer, 2009. 124(1): p. 16-26., https://www.ncbi.nlm.nih.gov/pubmed/18814281

155. Omholt, K., Karsberg, S., Platz, A., Kanter, L., Ringborg, U., Hansson, J., Screening of N-ras codon 61 mutations in paired primary and metastatic cutaneous melanomas: mutations occur early and persist throughout tumor progression, Clin Cancer Res, 2002. 8(11): p. 3468-74., https://www.ncbi.nlm.nih.gov/pubmed/12429636

156. Bloethner, S., Snellman, E., Bermejo, J. L., Hiripi, E., Gast, A., Thirumaran, R. K., et.al. Differential gene expression in melanocytic nevi with the V600E BRAF mutation, Genes Chromosomes Cancer, 2007. 46(11): p. 1019-27., https://www.ncbi.nlm.nih.gov/pubmed/17696195

157. Brose, M. S., Volpe, P., Feldman, M., Kumar, M., Rishi, I., Gerrero, R., et.al. BRAF and RAS mutations in human lung cancer and melanoma, Cancer Res, 2002. 62(23): p. 6997-7000., https://www.ncbi.nlm.nih.gov/pubmed/12460918

158. Davies, H., Bignell, G. R., Cox, C., Stephens, P., Edkins, S., Clegg, S., et.al. Mutations of the BRAF gene in human cancer, Nature, 2002. 417(6892): p. 949-54., https://www.ncbi.nlm.nih.gov/pubmed/12068308

159. Kumar, R., Angelini, S., Snellman, E., Hemminki, K., BRAF mutations are common somatic events in melanocytic nevi, J Invest Dermatol, 2004. 122(2): p. 342-8., https://www.ncbi.nlm.nih.gov/pubmed/15009715

160. Pollock, P. M., Harper, U. L., Hansen, K. S., Yudt, L. M., Stark, M., Robbins, C. M., et.al. High frequency of BRAF mutations in nevi, Nat Genet, 2003. 33(1): p. 19-20., https://www.ncbi.nlm.nih.gov/pubmed/12447372

161. Clark, W. H., Jr., Elder, D. E., Guerry, D. th, Braitman, L. E., Trock, B. J., Schultz, D., et.al. Model predicting survival in stage I melanoma based on tumor progression, J Natl Cancer Inst, 1989. 81(24): p. 1893-904., https://www.ncbi.nlm.nih.gov/pubmed/2593166

162. Schmid-Wendtner, M. H., Baumert, J., Eberle, J., Plewig, G., Volkenandt, M., Sander, C. A., Disease progression in patients with thin cutaneous melanomas (tumour thickness < or = 0.75 mm): clinical and epidemiological data from the Tumour Center Munich 1977-98, Br J Dermatol, 2003. 149(4): p. 788-93., https://www.ncbi.nlm.nih.gov/pubmed/14616371

163. Palmieri, G., Colombino, M., Casula, M., Manca, A., Mandala, M., Cossu, A., et.al. Molecular Pathways in Melanomagenesis: What We Learned from Next-Generation Sequencing Approaches, Curr Oncol Rep, 2018. 20(11): p. 86., https://www.ncbi.nlm.nih.gov/pubmed/30218391

164. Rivers, J. K., Is there more than one road to melanoma?, Lancet, 2004. 363(9410): p. 728-30., https://www.ncbi.nlm.nih.gov/pubmed/15005091

165. Maldonado, J. L., Fridlyand, J., Patel, H., Jain, A. N., Busam, K., Kageshita, T., et.al. Determinants of BRAF mutations in primary melanomas, J Natl Cancer Inst, 2003. 95(24): p. 1878-90., https://www.ncbi.nlm.nih.gov/pubmed/14679157

166. Sondak, V. K., Smalley, K., Targeting mutant BRAF and KIT in metastatic melanoma: ASCO 2009 meeting report, Pigment Cell Melanoma Res, 2009. 22(4): p. 386-7., https://www.ncbi.nlm.nih.gov/pubmed/19624312

167. Esteve-Puig, R., Canals, F., Colome, N., Merlino, G., Recio, J. A., Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF, PLoS One, 2009. 4(3): p. e4771., https://www.ncbi.nlm.nih.gov/pubmed/19274086

168. Lopez-Bergami, P., The long arm of BRAF V600E gets to mTORC1, Pigment Cell Melanoma Res, 2009. 22(3): p. 244-5., https://www.ncbi.nlm.nih.gov/pubmed/19338646

169. Zheng, B., Jeong, J. H., Asara, J. M., Yuan, Y. Y., Granter, S. R., Chin, L., et.al. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation, Mol Cell, 2009. 33(2): p. 237-47., https://www.ncbi.nlm.nih.gov/pubmed/19187764

170. Zerp, S. F., van Elsas, A., Peltenburg, L. T., Schrier, P. I., p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis, Br J Cancer, 1999. 79(5-6): p. 921-6., https://www.ncbi.nlm.nih.gov/pubmed/10070891

171. Whiteman, D. C., Parsons, P. G., Green, A. C., p53 expression and risk factors for cutaneous melanoma: a case-control study, Int J Cancer, 1998. 77(6): p. 843-8., https://www.ncbi.nlm.nih.gov/pubmed/9714052

172. Hoglund, M., Gisselsson, D., Hansen, G. B., White, V. A., Sall, T., Mitelman, F., et.al. Dissecting karyotypic patterns in malignant melanomas: temporal clustering of losses and gains in melanoma karyotypic evolution, Int J Cancer, 2004. 108(1): p. 57-65., https://www.ncbi.nlm.nih.gov/pubmed/14618616

173. Greinert, R., Breitbart, E.W., Volkmer, B., UV-radiation biology as part of cancer research, Life Science and radiation, 2004.

174. Li, G., Schaider, H., Satyamoorthy, K., Hanakawa, Y., Hashimoto, K., Herlyn, M., Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development, Oncogene, 2001. 20(56): p. 8125-35., https://www.ncbi.nlm.nih.gov/pubmed/11781826

175. Healy, E., Rehman, I., Angus, B., Rees, J. L., Loss of heterozygosity in sporadic primary cutaneous melanoma, Genes Chromosomes Cancer, 1995. 12(2): p. 152-6., https://www.ncbi.nlm.nih.gov/pubmed/7535089

176. Celebi, J. T., Shendrik, I., Silvers, D. N., Peacocke, M., Identification of PTEN mutations in metastatic melanoma specimens, J Med Genet, 2000. 37(9): p. 653-7., https://www.ncbi.nlm.nih.gov/pubmed/10978354

177. Pollock, P. M., Walker, G. J., Glendening, J. M., Que Noy, T., Bloch, N. C., Fountain, J. W., et.al. PTEN inactivation is rare in melanoma tumours but occurs frequently in melanoma cell lines, Melanoma Res, 2002. 12(6): p. 565-75., https://www.ncbi.nlm.nih.gov/pubmed/12459646

178. Stambolic, V., Suzuki, A., de la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., et.al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN, Cell, 1998. 95(1): p. 29-39., https://www.ncbi.nlm.nih.gov/pubmed/9778245

179. Blum, A., Epidemiologie und Risikofaktoren des malignen Melanoms, Onkologe, 2004. 10:

180. Robinson, J. K., Dahiya, M., Basal cell carcinoma with pulmonary and lymph node metastasis causing death, Arch Dermatol, 2003. 139(5): p. 643-8., https://www.ncbi.nlm.nih.gov/pubmed/12756102

181. LeBoit, P.E., Burg, G., Weedon, D., Sarasain, A., World Health Organization Classification of Tumours. Pathology and Genetics of Skin TumoursIARC Press, 2006.

182. Scrivener, Y., Grosshans, E., Cribier, B., Variations of basal cell carcinomas according to gender, age, location and histopathological subtype, Br J Dermatol, 2002. 147(1): p. 41-7., https://www.ncbi.nlm.nih.gov/pubmed/12100183

183. Union For International Cancer Control (UICC), John Wiley & Sons, Ltd., TNM-Klassifikation maligner Tumoren. Achte AuflageWILEY-VCH Verlag GmbH & Co. KGaA, Herausgegeben von Ch. Wittekind, 2017.

184. Karagas, M. R., Greenberg, E. R., Spencer, S. K., Stukel, T. A., Mott, L. A., Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA. New Hampshire Skin Cancer Study Group, Int J Cancer, 1999. 81(4): p. 555-9., https://www.ncbi.nlm.nih.gov/pubmed/10225444

185. Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V., GEKID-Atlas „Inzidenz und Mortalität von Krebserkrankungen in den Bundesländern; interaktiver Atlas der Gesellschaft für epidemiologische Krebsregister in Deutschland, 2019., http://www.ekr.med.uni-erlangen.de/GEKID/Atlas/CurrentVersion/Inzidenz/atlas.html

186. Eisemann, N., Jansen, L., Holleczek, B., Waldmann, A., Luttmann, S., Emrich, K., et.al. Up-to-date results on survival of patients with melanoma in Germany, Br J Dermatol, 2012. 167(3): p. 606-12., https://www.ncbi.nlm.nih.gov/pubmed/22564081

187. Robert Koch-Institut, Bericht zum Krebsgeschehen in Deutschland 2016, 2016.

188. Zentrum für Krebsregisterdaten und Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V., Krebs in Deutschland 2013/2014Robert Koch-Institut, Gesundheitsberichterstattung des Bundes, 2017.

189. Statistisches Bundesamt, Sterbefälle, Sterbeziffern (je 100.000 Einwohner, altersstandardisiert) (ab 1998). Gesundheitsberichterstattung des Bundes. Elektronische RessourceStatistisches Bundesamt, 2012. 2012:, http://www.gbe-bund.de

190. International Agency for Research on Cancer, Cancer Today. Data visualization tolls for exploring the global cancer burden in 2018, gco.iarc.fr/today/home

191. Arnold, M., Holterhues, C., Hollestein, L. M., Coebergh, J. W., Nijsten, T., Pukkala, E., et.al. Trends in incidence and predictions of cutaneous melanoma across Europe up to 2015, J Eur Acad Dermatol Venereol, 2014. 28(9): p. 1170-8., https://www.ncbi.nlm.nih.gov/pubmed/23962170

192. Brunssen, A., Jansen, L., Eisemann, N., Waldmann, A., Weberpals, J., Kraywinkel, K., et.al. Long-term relative survival from melanoma in Germany 1997-2013, Melanoma Res, 2020. 30(4): p. 386-395., https://www.ncbi.nlm.nih.gov/pubmed/30020195

193. Erdmann, F., Lortet-Tieulent, J., Schuz, J., Zeeb, H., Greinert, R., Breitbart, E. W., et.al. International trends in the incidence of malignant melanoma 1953-2008--are recent generations at higher or lower risk?, Int J Cancer, 2013. 132(2): p. 385-400., https://www.ncbi.nlm.nih.gov/pubmed/22532371

194. Australian Government: Cancer Australia, Cancer incidence, https://ncci.canceraustralia.gov.au/diagnosis/cancer-incidence/cancer-incidence

195. Aitken, J. F., Youlden, D. R., Baade, P. D., Soyer, H. P., Green, A. C., Smithers, B. M., Generational shift in melanoma incidence and mortality in Queensland, Australia, 1995-2014, Int J Cancer, 2018. 142(8): p. 1528-1535., https://www.ncbi.nlm.nih.gov/pubmed/29105744

196. Baade, P., Coory, M., Trends in melanoma mortality in Australia: 1950-2002 and their implications for melanoma control, Aust N Z J Public Health, 2005. 29(4): p. 383-6., https://www.ncbi.nlm.nih.gov/pubmed/16222938

197. Katalinic, A., Eisemann, N., Waldmann, A., Hautkrebsscreening in Deutschland. Erfassung der Melanominzidenz und -sterblichkeit von 2008 bis 2013. Skin Cancer Screening in Germany - Documenting Melanoma Incidence and Mortality From 2008 to 2013, Deutsches Ärzteblatt : Ausgabe A, Praxis-Ausgabe : niedergelassene Ärzte, 2015. 112(38):, http://www.zbmed.de/ccmedimages/2015/ZBMED-20159195155-3.pdf

198. Katalinic, A., Waldmann, A., Weinstock, M. A., Geller, A. C., Eisemann, N., Greinert, R., et.al. Does skin cancer screening save lives?: an observational study comparing trends in melanoma mortality in regions with and without screening, Cancer, 2012. 118(21): p. 5395-402., https://www.ncbi.nlm.nih.gov/pubmed/22517033

199. Veit, Ch., Lüken, F., Melsheimer, O., Evaluation der Screeninguntersuchungen auf Hautkrebs gemäß Krebsfrüherkennungs-Richtlinie des Gemeinsamen Bundesausschusses. Abschlussbericht 2009 –2010im Auftrag des Gemeinsamen Bundesausschusses, 2015.

200. Evaluation des bundesweiten Hautkrebsscreenings - Innovationsausschuss fördert Projekt EvaSCaUniversitätsklinikum Essen, 2019., https://www.uni-due.de/med/meldung.php?id=802

201. Katalinic, Alexander, Kunze, Uta, Schäfer, Torsten, Epidemiology of cutaneous melanoma and non-melanoma skin cancer in Schleswig-Holstein, Germany: incidence, clinical subtypes, tumour stages and localization (epidemiology of skin cancer), The British Journal of Dermatology, 2003. 149: p. 1200-1206.

202. Demers, A. A., Nugent, Z., Mihalcioiu, C., Wiseman, M. C., Kliewer, E. V., Trends of nonmelanoma skin cancer from 1960 through 2000 in a Canadian population, J Am Acad Dermatol, 2005. 53(2): p. 320-8., https://www.ncbi.nlm.nih.gov/pubmed/16021129

203. Brewster, D. H., Bhatti, L. A., Inglis, J. H., Nairn, E. R., Doherty, V. R., Recent trends in incidence of nonmelanoma skin cancers in the East of Scotland, 1992-2003, Br J Dermatol, 2007. 156(6): p. 1295-300., https://www.ncbi.nlm.nih.gov/pubmed/17535229

204. Bath-Hextall, F., Leonardi-Bee, J., Smith, C., Meal, A., Hubbard, R., Trends in incidence of skin basal cell carcinoma. Additional evidence from a UK primary care database study, Int J Cancer, 2007. 121(9): p. 2105-8., https://www.ncbi.nlm.nih.gov/pubmed/17640064

205. Breitbart, E. W., Waldmann, A., Nolte, S., Capellaro, M., Greinert, R., Volkmer, B., et.al. Systematic skin cancer screening in Northern Germany, J Am Acad Dermatol, 2012. 66(2): p. 201-11., https://www.ncbi.nlm.nih.gov/pubmed/22074699

206. Waldmann, A., Nolte, S., Weinstock, M. A., Breitbart, E. W., Eisemann, N., Geller, A. C., et.al. Skin cancer screening participation and impact on melanoma incidence in Germany--an observational study on incidence trends in regions with and without population-based screening, Br J Cancer, 2012. 106(5): p. 970-4., https://www.ncbi.nlm.nih.gov/pubmed/22294187

207. Hübner, J., Hübner, Franziska, Terheyden, Peter, Katalinic, A., Trendwende bei der Hautkrebsmortalität. Eine Analyse der Entwicklung in Deutschland 1998 bis 2017, Der Hautarzt, 2019. 70: p. 989–992.

208. Gallagher, R. P., Hill, G. B., Bajdik, C. D., Coldman, A. J., Fincham, S., McLean, D. I., et.al. Sunlight exposure, pigmentation factors, and risk of nonmelanocytic skin cancer. II. Squamous cell carcinoma, Arch Dermatol, 1995. 131(2): p. 164-9.

209. Gallagher, R. P., Hill, G. B., Bajdik, C. D., Fincham, S., Coldman, A. J., McLean, D. I., et.al. Sunlight exposure, pigmentary factors, and risk of nonmelanocytic skin cancer. I. Basal cell carcinoma, Arch Dermatol, 1995. 131(2): p. 157-63., https://www.ncbi.nlm.nih.gov/pubmed/7857111

210. Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Zanetti, R., Masini, C., et.al. Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors, Eur J Cancer, 2005. 41(14): p. 2040-59., https://www.ncbi.nlm.nih.gov/pubmed/16125929

211. Krengel, S., Scope, A., Dusza, S. W., Vonthein, R., Marghoob, A. A., New recommendations for the categorization of cutaneous features of congenital melanocytic nevi, J Am Acad Dermatol, 2013. 68(3): p. 441-51., https://www.ncbi.nlm.nih.gov/pubmed/22982004

212. Kinsler, V. A., Birley, J., Atherton, D. J., Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1-epidemiology, phenotype and outcomes, Br J Dermatol, 2009. 160(1): p. 143-50., https://www.ncbi.nlm.nih.gov/pubmed/18811688

213. Krengel, S., Hauschild, A., Schafer, T., Melanoma risk in congenital melanocytic naevi: a systematic review, Br J Dermatol, 2006. 155(1): p. 1-8., https://www.ncbi.nlm.nih.gov/pubmed/16792745

214. Price, H. N., Schaffer, J. V., Congenital melanocytic nevi-when to worry and how to treat: Facts and controversies, Clin Dermatol, 2010. 28(3): p. 293-302.

215. Castilla, E. E., da Graca Dutra, M., Orioli-Parreiras, I. M., Epidemiology of congenital pigmented naevi: II. Risk factors, Br J Dermatol, 1981. 104(4): p. 421-7.

216. Illig, L., Weidner, F., Hundeiker, M., Gartmann, H., Biess, B., Leyh, F., et.al. Congenital nevi less than or equal to 10 cm as precursors to melanoma. 52 cases, a review, and a new conception, Arch Dermatol, 1985. 121(10): p. 1274-81., https://www.ncbi.nlm.nih.gov/pubmed/4037820

217. Kinsler, V. A., Thomas, A. C., Ishida, M., Bulstrode, N. W., Loughlin, S., Hing, S., et.al. Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS, J Invest Dermatol, 2013. 133(9): p. 2229-36.

218. Bastian, B. C., Xiong, J., Frieden, I. J., Williams, M. L., Chou, P., Busam, K., et.al. Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas, Am J Pathol, 2002. 161(4): p. 1163-9.

219. Marcil, I., Stern, R. S., Risk of developing a subsequent nonmelanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis, Arch Dermatol, 2000. 136(12): p. 1524-30.

220. Frankel, D. H., Hanusa, B. H., Zitelli, J. A., New primary nonmelanoma skin cancer in patients with a history of squamous cell carcinoma of the skin. Implications and recommendations for follow-up, J Am Acad Dermatol, 1992. 26(5 Pt 1): p. 720-6., https://www.ncbi.nlm.nih.gov/pubmed/1583171

221. DiGiovanna, J. J., Posttransplantation skin cancer: scope of the problem, management, and role for systemic retinoid chemoprevention, Transplant Proc, 1998. 30(6): p. 2771-5; discussion 2776-8., https://www.ncbi.nlm.nih.gov/pubmed/9745564

222. Berg, D., Otley, C. C., Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management, J Am Acad Dermatol, 2002. 47(1): p. 1-17; quiz 18-20., https://www.ncbi.nlm.nih.gov/pubmed/12077575

223. Dantal, J., Hourmant, M., Cantarovich, D., Giral, M., Blancho, G., Dreno, B., et.al. Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens, Lancet, 1998. 351(9103): p. 623-8., https://www.ncbi.nlm.nih.gov/pubmed/9500317

224. Espana, A., Redondo, P., Fernandez, A. L., Zabala, M., Herreros, J., Llorens, R., et.al. Skin cancer in heart transplant recipients, J Am Acad Dermatol, 1995. 32(3): p. 458-65., https://www.ncbi.nlm.nih.gov/pubmed/7868716

225. Jensen, P., Hansen, S., Moller, B., Leivestad, T., Pfeffer, P., Geiran, O., et.al. Skin cancer in kidney and heart transplant recipients and different long-term immunosuppressive therapy regimens, J Am Acad Dermatol, 1999. 40(2 Pt 1): p. 177-86., https://www.ncbi.nlm.nih.gov/pubmed/10025742

226. Otley, C. C., Immunosuppression and skin cancer: pathogenetic insights, therapeutic challenges, and opportunities for innovation, Arch Dermatol, 2002. 138(6): p. 827-8., https://www.ncbi.nlm.nih.gov/pubmed/12056967

227. Preciado, D. A., Matas, A., Adams, G. L., Squamous cell carcinoma of the head and neck in solid organ transplant recipients, Head Neck, 2002. 24(4): p. 319-25., https://www.ncbi.nlm.nih.gov/pubmed/11933172

228. Marshall, V., Premalignant and malignant skin tumours in immunosuppressed patients, Transplantation, 1974. 17(3): p. 272-5., https://www.ncbi.nlm.nih.gov/pubmed/4592184

229. Euvrard, S., Kanitakis, J., Pouteil-Noble, C., Dureau, G., Touraine, J. L., Faure, M., et.al. Comparative epidemiologic study of premalignant and malignant epithelial cutaneous lesions developing after kidney and heart transplantation, J Am Acad Dermatol, 1995. 33(2 Pt 1): p. 222-9.

230. Fortina, A. B., Caforio, A. L., Piaserico, S., Alaibac, M., Tona, F., Feltrin, G., et.al. Skin cancer in heart transplant recipients: frequency and risk factor analysis, J Heart Lung Transplant, 2000. 19(3): p. 249-55., https://www.ncbi.nlm.nih.gov/pubmed/10713249

231. Gjersvik, P., Hansen, S., Moller, B., Leivestad, T., Geiran, O., Simonsen, S., et.al. Are heart transplant recipients more likely to develop skin cancer than kidney transplant recipients?, Transpl Int, 2000. 13 Suppl 1: p. S380-1., https://www.ncbi.nlm.nih.gov/pubmed/11112037

232. Naldi, L., Fortina, A. B., Lovati, S., Barba, A., Gotti, E., Tessari, G., et.al. Risk of nonmelanoma skin cancer in Italian organ transplant recipients. A registry-based study, Transplantation, 2000. 70(10): p. 1479-84.

233. Tessari, G., Naldi, L., Boschiero, L., Nacchia, F., Fior, F., Forni, A., et.al. Incidence and clinical predictors of a subsequent nonmelanoma skin cancer in solid organ transplant recipients with a first nonmelanoma skin cancer: a multicenter cohort study, Arch Dermatol, 2010. 146(3): p. 294-9.

234. Ong, C. S., Keogh, A. M., Kossard, S., Macdonald, P. S., Spratt, P. M., Skin cancer in Australian heart transplant recipients, J Am Acad Dermatol, 1999. 40(1): p. 27-34., https://www.ncbi.nlm.nih.gov/pubmed/9922009

235. Nguyen, P., Vin-Christian, K., Ming, M. E., Berger, T., Aggressive squamous cell carcinomas in persons infected with the human immunodeficiency virus, Arch Dermatol, 2002. 138(6): p. 758-63.

236. Lobo, D. V., Chu, P., Grekin, R. C., Berger, T. G., Nonmelanoma skin cancers and infection with the human immunodeficiency virus, Arch Dermatol, 1992. 128(5): p. 623-7.

237. Maurer, T. A., Christian, K. V., Kerschmann, R. L., Berzin, B., Palefsky, J. M., Payne, D., et.al. Cutaneous squamous cell carcinoma in human immunodeficiency virus-infected patients. A study of epidemiologic risk factors, human papillomavirus, and p53 expression, Arch Dermatol, 1997. 133(5): p. 577-83.

238. Wilkins, K., Turner, R., Dolev, J. C., LeBoit, P. E., Berger, T. G., Maurer, T. A., Cutaneous malignancy and human immunodeficiency virus disease, J Am Acad Dermatol, 2006. 54(2): p. 189-206; quiz 207-10.

239. Travis, L. B., Arndt, K. A., Occupational skin cancer. Four major carcinogens that put workers at risk, Postgrad Med, 1986. 79(6): p. 211-4, 217.

240. Karagas, M. R., McDonald, J. A., Greenberg, E. R., Stukel, T. A., Weiss, J. E., Baron, J. A., et.al. Risk of basal cell and squamous cell skin cancers after ionizing radiation therapy. For The Skin Cancer Prevention Study Group, J Natl Cancer Inst, 1996. 88(24): p. 1848-53.

241. Lichter, M. D., Karagas, M. R., Mott, L. A., Spencer, S. K., Stukel, T. A., Greenberg, E. R., Therapeutic ionizing radiation and the incidence of basal cell carcinoma and squamous cell carcinoma. The New Hampshire Skin Cancer Study Group, Arch Dermatol, 2000. 136(8): p. 1007-11.

242. Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Abeni, D., Boyle, P., et.al. Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi, Eur J Cancer, 2005. 41(1): p. 28-44., https://www.ncbi.nlm.nih.gov/pubmed/15617989

243. Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Picconi, O., Boyle, P., et.al. Meta-analysis of risk factors for cutaneous melanoma: II. Sun exposure, Eur J Cancer, 2005. 41(1): p. 45-60., https://www.ncbi.nlm.nih.gov/pubmed/15617990

244. Tucker, M. A., Boice, J. D., Jr., Hoffman, D. A., Second cancer following cutaneous melanoma and cancers of the brain, thyroid, connective tissue, bone, and eye in Connecticut, 1935-82, Natl Cancer Inst Monogr, 1985. 68: p. 161-89.

245. Ford, D., Bliss, J. M., Swerdlow, A. J., Armstrong, B. K., Franceschi, S., Green, A., et.al. Risk of cutaneous melanoma associated with a family history of the disease. The International Melanoma Analysis Group (IMAGE), Int J Cancer, 1995. 62(4): p. 377-81.

246. Hemminki, K., Lonnstedt, I., Vaittinen, P., A population-based study of familial cutaneous melanoma, Melanoma Res, 2001. 11(2): p. 133-40.

247. Brobeil, A., Rapaport, D., Wells, K., Cruse, C. W., Glass, F., Fenske, N., et.al. Multiple primary melanomas: implications for screening and follow-up programs for melanoma, Ann Surg Oncol, 1997. 4(1): p. 19-23.

248. Schmid-Wendtner, M. H., Baumert, J., Wendtner, C. M., Plewig, G., Volkenandt, M., Risk of second primary malignancies in patients with cutaneous melanoma, Br J Dermatol, 2001. 145(6): p. 981-5.

249. Bhatia, S., Estrada-Batres, L., Maryon, T., Bogue, M., Chu, D., Second primary tumors in patients with cutaneous malignant melanoma, Cancer, 1999. 86(10): p. 2014-20.

250. Wassberg, C., Thorn, M., Yuen, J., Ringborg, U., Hakulinen, T., Second primary cancers in patients with cutaneous malignant melanoma: a population-based study in Sweden, Br J Cancer, 1996. 73(2): p. 255-9.

251. Hübner, J., Eisemann, N., Brunßen, A., Katalinic, A., Hautkrebsscreening in Deutschland: Bilanz nach zehn Jahren, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2018.

252. Goldstein, A. M., Tucker, M. A., Genetic epidemiology of familial melanoma, Dermatol Clin, 1995. 13(3): p. 605-12.

253. Bauer, J., Garbe, C., Acquired melanocytic nevi as risk factor for melanoma development. A comprehensive review of epidemiological data, Pigment Cell Res, 2003. 16(3): p. 297-306., https://www.ncbi.nlm.nih.gov/pubmed/12753404

254. Bataille, V., Bishop, J. A., Sasieni, P., Swerdlow, A. J., Pinney, E., Griffiths, K., et.al. Risk of cutaneous melanoma in relation to the numbers, types and sites of naevi: a case-control study, Br J Cancer, 1996. 73(12): p. 1605-11.

255. Breitbart, M., Garbe, C., Buttner, P., Weiss, J., Soyer, H. P., Stocker, U., et.al. Ultraviolet light exposure, pigmentary traits and the development of melanocytic naevi and cutaneous melanoma. A case-control study of the German Central Malignant Melanoma Registry, Acta Derm Venereol, 1997. 77(5): p. 374-8.

256. Chang, Y. M., Newton-Bishop, J. A., Bishop, D. T., Armstrong, B. K., Bataille, V., Bergman, W., et.al. A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes, Int J Cancer, 2009. 124(2): p. 420-8.

257. Garbe, C., Buttner, P., Weiss, J., Soyer, H. P., Stocker, U., Kruger, S., et.al. Associated factors in the prevalence of more than 50 common melanocytic nevi, atypical melanocytic nevi, and actinic lentigines: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society, J Invest Dermatol, 1994. 102(5): p. 700-5.

258. Garbe, C., Buttner, P., Weiss, J., Soyer, H. P., Stocker, U., Kruger, S., et.al. Risk factors for developing cutaneous melanoma and criteria for identifying persons at risk: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society, J Invest Dermatol, 1994. 102(5): p. 695-9.

259. Grulich, A. E., Bataille, V., Swerdlow, A. J., Newton-Bishop, J. A., Cuzick, J., Hersey, P., et.al. Naevi and pigmentary characteristics as risk factors for melanoma in a high-risk population: a case-control study in New South Wales, Australia, Int J Cancer, 1996. 67(4): p. 485-91.

260. Hubner, J., Waldmann, A., Eisemann, N., Noftz, M., Geller, A. C., Weinstock, M. A., et.al. Association between risk factors and detection of cutaneous melanoma in the setting of a population-based skin cancer screening, Eur J Cancer Prev, 2018. 27(6): p. 563-569., https://www.ncbi.nlm.nih.gov/pubmed/28692584

261. Naldi, L., Lorenzo Imberti, G., Parazzini, F., Gallus, S., La Vecchia, C., Pigmentary traits, modalities of sun reaction, history of sunburns, and melanocytic nevi as risk factors for cutaneous malignant melanoma in the Italian population: results of a collaborative case-control study, Cancer, 2000. 88(12): p. 2703-10., https://www.ncbi.nlm.nih.gov/pubmed/8759605

262. Olsen, C. M., Zens, M. S., Green, A. C., Stukel, T. A., Holman, C. D., Mack, T., et.al. Biologic markers of sun exposure and melanoma risk in women: pooled case-control analysis, Int J Cancer, 2011. 129(3): p. 713-23.

263. Olsen, C. M., Zens, M. S., Stukel, T. A., Sacerdote, C., Chang, Y. M., Armstrong, B. K., et.al. Nevus density and melanoma risk in women: a pooled analysis to test the divergent pathway hypothesis, Int J Cancer, 2009. 124(4): p. 937-44., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035752/

264. Rodenas, J. M., Delgado-Rodriguez, M., Herranz, M. T., Tercedor, J., Serrano, S., Sun exposure, pigmentary traits, and risk of cutaneous malignant melanoma: a case-control study in a Mediterranean population, Cancer Causes Control, 1996. 7(2): p. 275-83.

265. White, E., Kirkpatrick, C. S., Lee, J. A., Case-control study of malignant melanoma in Washington State. I. Constitutional factors and sun exposure, Am J Epidemiol, 1994. 139(9): p. 857-68.

266. Bataille, V., Snieder, H., MacGregor, A. J., Sasieni, P., Spector, T. D., Genetics of risk factors for melanoma: an adult twin study of nevi and freckles, J Natl Cancer Inst, 2000. 92(6): p. 457-63.

267. Easton, D. F., Cox, G. M., Macdonald, A. M., Ponder, B. A., Genetic susceptibility to naevi--a twin study, Br J Cancer, 1991. 64(6): p. 1164-7.

268. Green, A., Siskind, V., Hansen, M. E., Hanson, L., Leech, P., Melanocytic nevi in schoolchildren in Queensland, J Am Acad Dermatol, 1989. 20(6): p. 1054-60.

269. Green, A. C., Wallingford, S. C., McBride, P., Childhood exposure to ultraviolet radiation and harmful skin effects: epidemiological evidence, Prog Biophys Mol Biol, 2011. 107(3): p. 349-55.

270. Gallagher, R. P., McLean, D. I., Yang, C. P., Coldman, A. J., Silver, H. K., Spinelli, J. J., et.al. Suntan, sunburn, and pigmentation factors and the frequency of acquired melanocytic nevi in children. Similarities to melanoma: the Vancouver Mole Study, Arch Dermatol, 1990. 126(6): p. 770-6., https://www.ncbi.nlm.nih.gov/pubmed/2346321

271. Harrison, S. L., MacLennan, R., Buettner, P. G., Sun exposure and the incidence of melanocytic nevi in young Australian children, Cancer Epidemiol Biomarkers Prev, 2008. 17(9): p. 2318-24.

272. Kelly, J. W., Rivers, J. K., MacLennan, R., Harrison, S., Lewis, A. E., Tate, B. J., Sunlight: a major factor associated with the development of melanocytic nevi in Australian schoolchildren, J Am Acad Dermatol, 1994. 30(1): p. 40-8.

273. Richard, M. A., Grob, J. J., Gouvernet, J., Culat, J., Normand, P., Zarour, H., et.al. Role of sun exposure on nevus. First study in age-sex phenotype-controlled populations, Arch Dermatol, 1993. 129(10): p. 1280-5.

274. Dulon, M., Weichenthal, M., Blettner, M., Breitbart, M., Hetzer, M., Greinert, R., et.al. Sun exposure and number of nevi in 5- to 6-year-old European children, J Clin Epidemiol, 2002. 55(11): p. 1075-81.

275. Wiecker, T. S., Luther, H., Buettner, P., Bauer, J., Garbe, C., Moderate sun exposure and nevus counts in parents are associated with development of melanocytic nevi in childhood: a risk factor study in 1,812 kindergarten children, Cancer, 2003. 97(3): p. 628-38.

276. Grob, J. J., Gouvernet, J., Aymar, D., Mostaque, A., Romano, M. H., Collet, A. M., et.al. Count of benign melanocytic nevi as a major indicator of risk for nonfamilial nodular and superficial spreading melanoma, Cancer, 1990. 66(2): p. 387-95.

277. Holly, E. A., Kelly, J. W., Shpall, S. N., Chiu, S. H., Number of melanocytic nevi as a major risk factor for malignant melanoma, J Am Acad Dermatol, 1987. 17(3): p. 459-68.

278. Halpern, A. C., Guerry, D. th, Elder, D. E., Clark, W. H., Jr., Synnestvedt, M., Norman, S., et.al. Dysplastic nevi as risk markers of sporadic (nonfamilial) melanoma. A case-control study, Arch Dermatol, 1991. 127(7): p. 995-9.

279. de Gruijl, F. R., van Kranen, H. J., Mullenders, L. H., UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer, J Photochem Photobiol B, 2001. 63(1-3): p. 19-27.

280. Savoye, I., Olsen, C. M., Whiteman, D. C., Bijon, A., Wald, L., Dartois, L., et.al. Patterns of Ultraviolet Radiation Exposure and Skin Cancer Risk: the E3N-SunExp Study, J Epidemiol, 2018. 28(1): p. 27-33., https://www.ncbi.nlm.nih.gov/pubmed/29176271

281. Schmitt, J., Haufe, E., Trautmann, F., Schulze, H. J., Elsner, P., Drexler, H., et.al. Is ultraviolet exposure acquired at work the most important risk factor for cutaneous squamous cell carcinoma? Results of the population-based case-control study FB-181, Br J Dermatol, 2018. 178(2): p. 462-472., https://www.ncbi.nlm.nih.gov/pubmed/28845516

282. Iannacone, M. R., Wang, W., Stockwell, H. G., O'Rourke, K., Giuliano, A. R., Sondak, V. K., et.al. Patterns and timing of sunlight exposure and risk of basal cell and squamous cell carcinomas of the skin--a case-control study, BMC Cancer, 2012. 12: p. 417., https://www.ncbi.nlm.nih.gov/pubmed/22994655

283. Schmitt, J., Haufe, E., Trautmann, F., Schulze, H. J., Elsner, P., Drexler, H., et.al. Occupational UV-Exposure is a Major Risk Factor for Basal Cell Carcinoma: Results of the Population-Based Case-Control Study FB-181, J Occup Environ Med, 2018. 60(1): p. 36-43., https://www.ncbi.nlm.nih.gov/pubmed/29111985

284. National Institutes of Health summary of the Consensus Development Conference on Sunlight, U.R., and the Skin, Bethesda, Maryland, May 8-10, 1989. Consensus Development Panel,, J Am Acad Dermatol, 1991. 24(4): p. 608-12., 1991.

285. Dubin, N., Moseson, M., Pasternack, B. S., Sun exposure and malignant melanoma among susceptible individuals, Environ Health Perspect, 1989. 81: p. 139-51., https://www.ncbi.nlm.nih.gov/pubmed/2759056

286. Whiteman, D., Green, A., Melanoma and sunburn, Cancer Causes Control, 1994. 5(6): p. 564-72., https://www.ncbi.nlm.nih.gov/pubmed/7827244

287. Greenland, S., Quantitative methods in the review of epidemiologic literature, Epidemiol Rev, 1987. 9: p. 1-30., https://www.ncbi.nlm.nih.gov/pubmed/3678409

288. Elwood, J. M., Jopson, J., Melanoma and sun exposure: an overview of published studies, Int J Cancer, 1997. 73(2): p. 198-203., https://www.ncbi.nlm.nih.gov/pubmed/9335442

289. Nelemans, P. J., Rampen, F. H., Ruiter, D. J., Verbeek, A. L., An addition to the controversy on sunlight exposure and melanoma risk: a meta-analytical approach, J Clin Epidemiol, 1995. 48(11): p. 1331-42., https://www.ncbi.nlm.nih.gov/pubmed/7490596

290. Stang, A., Pukkala, E., Sankila, R., Soderman, B., Hakulinen, T., Time trend analysis of the skin melanoma incidence of Finland from 1953 through 2003 including 16,414 cases, Int J Cancer, 2006. 119(2): p. 380-4., https://www.ncbi.nlm.nih.gov/pubmed/16477634

291. Stang, A., Valiukeviciene, S., Aleknaviciene, B., Kurtinaitis, J., Time trends of incidence, mortality, and relative survival of invasive skin melanoma in Lithuania, Eur J Cancer, 2006. 42(5): p. 660-7., https://www.ncbi.nlm.nih.gov/pubmed/16510281

292. Cullen, A. P., Photokeratitis and other phototoxic effects on the cornea and conjunctiva, Int J Toxicol, 2002. 21(6): p. 455-64., https://www.ncbi.nlm.nih.gov/pubmed/12537642

293. Oliva, M. S., Taylor, H., Ultraviolet radiation and the eye, Int Ophthalmol Clin, 2005. 45(1): p. 1-17., https://www.ncbi.nlm.nih.gov/pubmed/15632523

294. Ren, H., Wilson, G., The effect of ultraviolet-B irradiation on the cell shedding rate of the corneal epithelium, Acta Ophthalmol (Copenh), 1994. 72(4): p. 447-52., https://www.ncbi.nlm.nih.gov/pubmed/7825410

295. Chen, K. C., Jung, J. J., Aizman, A., High definition spectral domain optical coherence tomography findings in three patients with solar retinopathy and review of the literature, Open Ophthalmol J, 2012. 6: p. 29-35., https://www.ncbi.nlm.nih.gov/pubmed/22798967

296. Comander, J., Gardiner, M., Loewenstein, J., High-resolution optical coherence tomography findings in solar maculopathy and the differential diagnosis of outer retinal holes, Am J Ophthalmol, 2011. 152(3): p. 413-419 e6., https://www.ncbi.nlm.nih.gov/pubmed/21708377

297. Cameron, M, Pterygium throughout the worldCharles C. Thomas, 1992.

298. Mackenzie, F. D., Hirst, L. W., Battistutta, D., Green, A., Risk analysis in the development of pterygia, Ophthalmology, 1992. 99(7): p. 1056-61., https://www.ncbi.nlm.nih.gov/pubmed/1495784

299. Moran, D. J., Hollows, F. C., Pterygium and ultraviolet radiation: a positive correlation, Br J Ophthalmol, 1984. 68(5): p. 343-6., https://www.ncbi.nlm.nih.gov/pubmed/6712914

300. Taylor, H. R., West, S. K., Rosenthal, F. S., Munoz, B., Newland, H. S., Emmett, E. A., Corneal changes associated with chronic UV irradiation, Arch Ophthalmol, 1989. 107(10): p. 1481-4., https://www.ncbi.nlm.nih.gov/pubmed/2803097

301. Norn, M. S., Spheroid degeneration, pinguecula, and pterygium among Arabs in the Red Sea territory, Jordan, Acta Ophthalmol (Copenh), 1982. 60(6): p. 949-54., https://www.ncbi.nlm.nih.gov/pubmed/7170936

302. Gray, R. H., Johnson, G. J., Freedman, A., Climatic droplet keratopathy, Surv Ophthalmol, 1992. 36(4): p. 241-53., https://www.ncbi.nlm.nih.gov/pubmed/1549808

303. Johnson, G. J., Aetiology of spheroidal degeneration of the cornea in Labrador, Br J Ophthalmol, 1981. 65(4): p. 270-83., https://www.ncbi.nlm.nih.gov/pubmed/7236572

304. Klintworth, G. K., Chronic actinic keratopathy--a condition associated with conjunctival elastosis (pingueculae) and typified by characteristic extracellular concretions, Am J Pathol, 1972. 67(2): p. 327-48., https://www.ncbi.nlm.nih.gov/pubmed/5021106

305. Pe'er, J., Ocular surface squamous neoplasia: evidence for topical chemotherapy, Int Ophthalmol Clin, 2015. 55(1): p. 9-21., https://www.ncbi.nlm.nih.gov/pubmed/25436490

306. Lee, G. A., Hirst, L. W., Incidence of ocular surface epithelial dysplasia in metropolitan Brisbane. A 10-year survey, Arch Ophthalmol, 1992. 110(4): p. 525-7., https://www.ncbi.nlm.nih.gov/pubmed/1562262

307. Malik, M. O., El Sheikh, E. H., Tumors of the eye and adnexa in the Sudan, Cancer, 1979. 44(1): p. 293-303., https://www.ncbi.nlm.nih.gov/pubmed/455254

308. Newton, R., Ferlay, J., Reeves, G., Beral, V., Parkin, D. M., Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye, Lancet, 1996. 347(9013): p. 1450-1., https://www.ncbi.nlm.nih.gov/pubmed/8676629

309. Pola, E. C., Masanganise, R., Rusakaniko, S., The trend of ocular surface squamous neoplasia among ocular surface tumour biopsies submitted for histology from Sekuru Kaguvi Eye Unit, Harare between 1996 and 2000, Cent Afr J Med, 2003. 49(1-2): p. 1-4., https://www.ncbi.nlm.nih.gov/pubmed/14562592

310. Sun, E. C., Fears, T. R., Goedert, J. J., Epidemiology of squamous cell conjunctival cancer, Cancer Epidemiol Biomarkers Prev, 1997. 6(2): p. 73-7., https://www.ncbi.nlm.nih.gov/pubmed/9037556

311. Templeton, A. C., Tumors of the eye and adnexa in Africans of Uganda, Cancer, 1967. 20(10): p. 1689-98., https://www.ncbi.nlm.nih.gov/pubmed/6058176

312. El-Shabrawi, Y., Radner, H., Muellner, K., Langmann, G., Hoefler, G., The role of UV-radiation in the development of conjunctival malignant melanoma, Acta Ophthalmol Scand, 1999. 77(1): p. 31-2., https://www.ncbi.nlm.nih.gov/pubmed/10071144

313. Brilliant, L. B., Grasset, N. C., Pokhrel, R. P., Kolstad, A., Lepkowski, J. M., Brilliant, G. E., et.al. Associations among cataract prevalence, sunlight hours, and altitude in the Himalayas, Am J Epidemiol, 1983. 118(2): p. 250-64., https://www.ncbi.nlm.nih.gov/pubmed/6603790

314. Chatterjee, A., Milton, R. C., Thyle, S., Prevalence and aetiology of cataract in Punjab, Br J Ophthalmol, 1982. 66(1): p. 35-42., https://www.ncbi.nlm.nih.gov/pubmed/7055541

315. Hollows, F., Moran, D., Cataract--the ultraviolet risk factor, Lancet, 1981. 2(8258): p. 1249-50., https://www.ncbi.nlm.nih.gov/pubmed/6118668

316. Taylor, H. R., The environment and the lens, Br J Ophthalmol, 1980. 64(5): p. 303-10., https://www.ncbi.nlm.nih.gov/pubmed/7437389

317. Wong, L., Ho, S. C., Coggon, D., Cruddas, A. M., Hwang, C. H., Ho, C. P., et.al. Sunlight exposure, antioxidant status, and cataract in Hong Kong fishermen, J Epidemiol Community Health, 1993. 47(1): p. 46-9., https://www.ncbi.nlm.nih.gov/pubmed/8436894

318. Bochow, T. W., West, S. K., Azar, A., Munoz, B., Sommer, A., Taylor, H. R., Ultraviolet light exposure and risk of posterior subcapsular cataracts, Arch Ophthalmol, 1989. 107(3): p. 369-72., https://www.ncbi.nlm.nih.gov/pubmed/2923558

319. Cruickshanks, K. J., Klein, B. E., Klein, R., Ultraviolet light exposure and lens opacities: the Beaver Dam Eye Study, Am J Public Health, 1992. 82(12): p. 1658-62., https://www.ncbi.nlm.nih.gov/pubmed/1456342

320. Hyman, L. G., Lilienfeld, A. M., Ferris, F. L., 3rd, Fine, S. L., Senile macular degeneration: a case-control study, Am J Epidemiol, 1983. 118(2): p. 213-27., https://www.ncbi.nlm.nih.gov/pubmed/6881127

321. Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group, Arch Ophthalmol, 1992. 110(12): p. 1701-8., https://www.ncbi.nlm.nih.gov/pubmed/1281403

322. Darzins, P., Mitchell, P., Heller, R. F., Sun exposure and age-related macular degeneration. An Australian case-control study, Ophthalmology, 1997. 104(5): p. 770-6., https://www.ncbi.nlm.nih.gov/pubmed/9160021

323. West, S. K., Rosenthal, F. S., Bressler, N. M., Bressler, S. B., Munoz, B., Fine, S. L., et.al. Exposure to sunlight and other risk factors for age-related macular degeneration, Arch Ophthalmol, 1989. 107(6): p. 875-9., https://www.ncbi.nlm.nih.gov/pubmed/2786410

324. Taylor, H. R., West, S., Munoz, B., Rosenthal, F. S., Bressler, S. B., Bressler, N. M., The long-term effects of visible light on the eye, Arch Ophthalmol, 1992. 110(1): p. 99-104., https://www.ncbi.nlm.nih.gov/pubmed/1731731

325. Sui, G. Y., Liu, G. C., Liu, G. Y., Gao, Y. Y., Deng, Y., Wang, W. Y., et.al. Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis, Br J Ophthalmol, 2013. 97(4): p. 389-94., https://www.ncbi.nlm.nih.gov/pubmed/23143904

326. Wang, J. J., Klein, R., Smith, W., Klein, B. E., Tomany, S., Mitchell, P., Cataract surgery and the 5-year incidence of late-stage age-related maculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies, Ophthalmology, 2003. 110(10): p. 1960-7., https://www.ncbi.nlm.nih.gov/pubmed/14522772

327. Downie, L. E., Busija, L., Keller, P. R., Blue-light filtering intraocular lenses (IOLs) for protecting macular health, Cochrane Database Syst Rev, 2018. 5: p. CD011977., https://www.ncbi.nlm.nih.gov/pubmed/29786830

328. Partanen, T., Boffetta, P., Cancer risk in asphalt workers and roofers: review and meta-analysis of epidemiologic studies, Am J Ind Med, 1994. 26(6): p. 721-40., https://www.ncbi.nlm.nih.gov/pubmed/7892824

329. Tsai, P. J., Shieh, H. Y., Lee, W. J., Lai, S. O., Health-risk assessment for workers exposed to polycyclic aromatic hydrocarbons (PAHs) in a carbon black manufacturing industry, Sci Total Environ, 2001. 278(1-3): p. 137-50., https://www.ncbi.nlm.nih.gov/pubmed/11669262

330. Roelofzen, J. H., Aben, K. K., Oldenhof, U. T., Coenraads, P. J., Alkemade, H. A., van de Kerkhof, P. C., et.al. No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema, J Invest Dermatol, 2010. 130(4): p. 953-61., https://www.ncbi.nlm.nih.gov/pubmed/20016499

331. Forslund, O., Iftner, T., Andersson, K., Lindelof, B., Hradil, E., Nordin, P., et.al. Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma, J Infect Dis, 2007. 196(6): p. 876-83., https://www.ncbi.nlm.nih.gov/pubmed/17703418

332. Kelly, D. A., Young, A. R., McGregor, J. M., Seed, P. T., Potten, C. S., Walker, S. L., Sensitivity to sunburn is associated with susceptibility to ultraviolet radiation-induced suppression of cutaneous cell-mediated immunity, J Exp Med, 2000. 191(3): p. 561-6., https://www.ncbi.nlm.nih.gov/pubmed/10662801

333. Pedersen, S. A., Gaist, D., Schmidt, S. A. J., Holmich, L. R., Friis, S., Pottegard, A., Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark, J Am Acad Dermatol, 2018. 78(4): p. 673-681 e9., https://www.ncbi.nlm.nih.gov/pubmed/29217346

334. Pottegard, A., Hallas, J., Olesen, M., Svendsen, M. T., Habel, L. A., Friedman, G. D., et.al. Hydrochlorothiazide use is strongly associated with risk of lip cancer, J Intern Med, 2017. 282(4): p. 322-331., https://www.ncbi.nlm.nih.gov/pubmed/28480532

335. Kulasingam, V., Diamandis, E. P., Strategies for discovering novel cancer biomarkers through utilization of emerging technologies, Nat Clin Pract Oncol, 2008. 5(10): p. 588-99., https://www.ncbi.nlm.nih.gov/pubmed/18695711

336. Ludwig, J. A., Weinstein, J. N., Biomarkers in cancer staging, prognosis and treatment selection, Nat Rev Cancer, 2005. 5(11): p. 845-56., https://www.ncbi.nlm.nih.gov/pubmed/16239904

337. Neagu, M., Constantin, C., Cretoiu, S. M., Zurac, S., miRNAs in the Diagnosis and Prognosis of Skin Cancer, Front Cell Dev Biol, 2020. 8: p. 71., https://www.ncbi.nlm.nih.gov/pubmed/32185171

338. Weinstein, D., Leininger, J., Hamby, C., Safai, B., Diagnostic and prognostic biomarkers in melanoma, J Clin Aesthet Dermatol, 2014. 7(6): p. 13-24., https://www.ncbi.nlm.nih.gov/pubmed/25013535

339. Chen, J. J., Lu, T. P., Chen, Y. C., Lin, W. J., Predictive biomarkers for treatment selection: statistical considerations, Biomark Med, 2015. 9(11): p. 1121-35., https://www.ncbi.nlm.nih.gov/pubmed/26507127

340. Chen, G., Huang, A. C., Zhang, W., Zhang, G., Wu, M., Xu, W., et.al. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response, Nature, 2018. 560(7718): p. 382-386., https://www.ncbi.nlm.nih.gov/pubmed/30089911

341. Kalia, M., Biomarkers for personalized oncology: recent advances and future challenges, Metabolism, 2015. 64(3 Suppl 1): p. S16-21., https://www.ncbi.nlm.nih.gov/pubmed/25468140

342. Gaiser, M. R., von Bubnoff, N., Gebhardt, C., Utikal, J. S., Liquid biopsy to monitor melanoma patients, J Dtsch Dermatol Ges, 2018. 16(4): p. 405-414., https://www.ncbi.nlm.nih.gov/pubmed/29512873

343. Lianidou, E., Pantel, K., Liquid biopsies, Genes Chromosomes Cancer, 2019. 58(4): p. 219-232., https://www.ncbi.nlm.nih.gov/pubmed/30382599

344. Reimers, N., Pantel, K., Liquid biopsy: novel technologies and clinical applications, Clin Chem Lab Med, 2019. 57(3): p. 312-316., https://www.ncbi.nlm.nih.gov/pubmed/30465714

345. Quandt, D., Dieter Zucht, H., Amann, A., Wulf-Goldenberg, A., Borrebaeck, C., Cannarile, M., et.al. Implementing liquid biopsies into clinical decision making for cancer immunotherapy, Oncotarget, 2017. 8(29): p. 48507-48520., https://www.ncbi.nlm.nih.gov/pubmed/28501851

346. Dragomir, M., Mafra, A. C. P., Dias, S. M. G., Vasilescu, C., Calin, G. A., Using microRNA Networks to Understand Cancer, Int J Mol Sci, 2018. 19(7):, https://www.ncbi.nlm.nih.gov/pubmed/29949872

347. Whiteside, T. L., Tumor-Derived Exosomes and Their Role in Cancer Progression, Adv Clin Chem, 2016. 74: p. 103-41., https://www.ncbi.nlm.nih.gov/pubmed/27117662

348. Lim, S. Y., Lee, J. H., Diefenbach, R. J., Kefford, R. F., Rizos, H., Liquid biomarkers in melanoma: detection and discovery, Mol Cancer, 2018. 17(1): p. 8., https://www.ncbi.nlm.nih.gov/pubmed/29343260

349. Mumford, S. L., Towler, B. P., Pashler, A. L., Gilleard, O., Martin, Y., Newbury, S. F., Circulating MicroRNA Biomarkers in Melanoma: Tools and Challenges in Personalised Medicine, Biomolecules, 2018. 8(2):, https://www.ncbi.nlm.nih.gov/pubmed/29701682

350. Sharma, P., Diergaarde, B., Ferrone, S., Kirkwood, J. M., Whiteside, T. L., Melanoma cell-derived exosomes in plasma of melanoma patients suppress functions of immune effector cells, Sci Rep, 2020. 10(1): p. 92., https://www.ncbi.nlm.nih.gov/pubmed/31919420

351. Zhang, Y., Liu, Y., Liu, H., Tang, W. H., Exosomes: biogenesis, biologic function and clinical potential, Cell Biosci, 2019. 9: p. 19., https://www.ncbi.nlm.nih.gov/pubmed/30815248

352. Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Zanetti, R., Masini, C., et.al. Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors, Eur J Cancer, 2005. 41(14): p. 2040-59., https://www.ncbi.nlm.nih.gov/pubmed/16125929

353. Gandini, S., Sera, F., Cattaruzza, M. S., Pasquini, P., Picconi, O., Boyle, P., et.al. Meta-analysis of risk factors for cutaneous melanoma: II. Sun exposure, Eur J Cancer, 2005. 41(1): p. 45-60., https://www.ncbi.nlm.nih.gov/pubmed/15617990

354. Neale, R. E., Davis, M., Pandeya, N., Whiteman, D. C., Green, A. C., Basal cell carcinoma on the trunk is associated with excessive sun exposure, J Am Acad Dermatol, 2007. 56(3): p. 380-6., https://www.ncbi.nlm.nih.gov/pubmed/17097387

355. World Health Organization, Global Solar UV Index: A Practical Guide., 2002.

356. Autier, P., Boniol, M., Dore, J. F., Sunscreen use and increased duration of intentional sun exposure: still a burning issue, Int J Cancer, 2007. 121(1): p. 1-5., https://www.ncbi.nlm.nih.gov/pubmed/17415716

357. Autier, P., Dore, J. F., Reis, A. C., Grivegnee, A., Ollivaud, L., Truchetet, F., et.al. Sunscreen use and intentional exposure to ultraviolet A and B radiation: A double blind randomized trial using personal dosimeters, British Journal of Cancer, 2000. p. 83(9)(pp 1243-1248).

358. Autier, P., Dore, J. F., Schifflers, E., Cesarini, J. P., Bollaerts, A., Koelmel, K. F., et.al. Melanoma and use of sunscreens: an Eortc case-control study in Germany, Belgium and France. The EORTC Melanoma Cooperative Group, Int J Cancer, 1995. 61(6): p. 749-55., https://www.ncbi.nlm.nih.gov/pubmed/7790106

359. Gorham, E. D., Mohr, S. B., Garland, C. F., Chaplin, G., Garland, F. C., Do sunscreens increase risk of melanoma in populations residing at higher latitudes?, Ann Epidemiol, 2007. 17(12): p. 956-63., https://www.ncbi.nlm.nih.gov/pubmed/18022535

360. Green, A. C., Williams, G. M., Logan, V., Strutton, G. M., Reduced melanoma after regular sunscreen use: randomized trial follow-up, J Clin Oncol, 2011. 29(3): p. 257-63., https://www.ncbi.nlm.nih.gov/pubmed/21135266

361. Lin, J. S., Eder, M., Weinmann, S., Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force, Ann Intern Med, 2011. 154(3): p. 190-201., https://www.ncbi.nlm.nih.gov/pubmed/21282699

362. Darlington, S., Williams, G., Neale, R., Frost, C., Green, A., A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses, Arch Dermatol, 2003. 139(4): p. 451-5., https://www.ncbi.nlm.nih.gov/pubmed/12707092

363. Dennis, L. K., Beane Freeman, L. E., VanBeek, M. J., Sunscreen use and the risk for melanoma: a quantitative review, Ann Intern Med, 2003. 139(12): p. 966-78., https://www.ncbi.nlm.nih.gov/pubmed/14678916

364. Kulichova, D., Danova, J., Kunte, C., Ruzicka, T., Celko, A. M., Risk factors for malignant melanoma and preventive methods, Cutis, 2014. 94(5): p. 241-8., https://www.ncbi.nlm.nih.gov/pubmed/25474453

365. Ghiasvand, R., Weiderpass, E., Green, A. C., Lund, E., Veierod, M. B., Sunscreen Use and Subsequent Melanoma Risk: A Population-Based Cohort Study, J Clin Oncol, 2016. 34(33): p. 3976-3983., https://www.ncbi.nlm.nih.gov/pubmed/27621396

366. European Commission, Policies, information and services: Sunscreen products, https://ec.europa.eu/growth/sectors/cosmetics/products/sunscreen_en

367. Huncharek, M., Kupelnick, B., Use of topical sunscreens and the risk of malignant melanoma: a meta-analysis of 9067 patients from 11 case-control studies, Am J Public Health, 2002. 92(7): p. 1173-7., https://www.ncbi.nlm.nih.gov/pubmed/12084704

368. Autier, P., Dore, J. F., Reis, A. C., Grivegnee, A., Ollivaud, L., Truchetet, F., et.al. Sunscreen use and intentional exposure to ultraviolet A and B radiation: A double blind randomized trial using personal dosimeters, British Journal of Cancer, 2000. p. 83(9)(pp 1243-1248), 2000., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363574/

369. Matta, M. K., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., Florian, J., et.al. Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial, JAMA, 2019. 321(21): p. 2082-2091., https://www.ncbi.nlm.nih.gov/pubmed/31058986

370. Colantonio, S., Bracken, M. B., Beecker, J., The association of indoor tanning and melanoma in adults: systematic review and meta-analysis, J Am Acad Dermatol, 2014. 70(5): p. 847-57 e1-18., https://www.ncbi.nlm.nih.gov/pubmed/24629998

371. Burgard, B., Schope, J., Holzschuh, I., Schiekofer, C., Reichrath, S., Stefan, W., et.al. Solarium Use and Risk for Malignant Melanoma: Meta-analysis and Evidence-based Medicine Systematic Review, Anticancer Res, 2018. 38(2): p. 1187-1199., https://www.ncbi.nlm.nih.gov/pubmed/29374757

372. Boniol, M., Autier, P., Boyle, P., Gandini, S., Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis, BMJ, 2012. 345: p. e4757., https://www.ncbi.nlm.nih.gov/pubmed/22833605

373. Ghiasvand, R., Rueegg, C. S., Weiderpass, E., Green, A. C., Lund, E., Veierod, M. B., Indoor Tanning and Melanoma Risk: Long-Term Evidence From a Prospective Population-Based Cohort Study, Am J Epidemiol, 2017. 185(3): p. 147-156., https://www.ncbi.nlm.nih.gov/pubmed/28077359

374. Karagas, M. R., Zens, M. S., Li, Z., Stukel, T. A., Perry, A. E., Gilbert-Diamond, D., et.al. Early-onset basal cell carcinoma and indoor tanning: a population-based study, Pediatrics, 2014. 134(1): p. e4-12., https://www.ncbi.nlm.nih.gov/pubmed/24958589

375. Wehner, M. R., Shive, M. L., Chren, M. M., Han, J., Qureshi, A. A., Linos, E., Indoor tanning and non-melanoma skin cancer: systematic review and meta-analysis, BMJ, 2012. 345: p. e5909., https://www.ncbi.nlm.nih.gov/pubmed/23033409

376. Green, A., Williams, G., Neale, R., Hart, V., Leslie, D., Parsons, P., et.al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial, Lancet, 1999. 354(9180): p. 723-9., https://www.ncbi.nlm.nih.gov/pubmed/10475183

377. Myung, S. K., Kim, Y., Ju, W., Choi, H. J., Bae, W. K., Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials, Ann Oncol, 2010. 21(1): p. 166-79., https://www.ncbi.nlm.nih.gov/pubmed/19622597

378. Lukic, M., Jareid, M., Weiderpass, E., Braaten, T., Coffee consumption and the risk of malignant melanoma in the Norwegian Women and Cancer (NOWAC) Study, BMC Cancer, 2016. 16: p. 562., https://www.ncbi.nlm.nih.gov/pubmed/27473841

379. Miura, K., Hughes, M. C., Green, A. C., van der Pols, J. C., Caffeine intake and risk of basal cell and squamous cell carcinomas of the skin in an 11-year prospective study, Eur J Nutr, 2014. 53(2): p. 511-20., https://www.ncbi.nlm.nih.gov/pubmed/23824258

380. Liu, J., Shen, B., Shi, M., Cai, J., Higher Caffeinated Coffee Intake Is Associated with Reduced Malignant Melanoma Risk: A Meta-Analysis Study, PLoS One, 2016. 11(1): p. e0147056., https://www.ncbi.nlm.nih.gov/pubmed/26816289

381. Rollison, D. E., Iannacone, M. R., Messina, J. L., Glass, L. F., Giuliano, A. R., Roetzheim, R. G., et.al. Case-control study of smoking and non-melanoma skin cancer, Cancer Causes Control, 2012. 23(2): p. 245-54., https://www.ncbi.nlm.nih.gov/pubmed/22101452

382. Kubo, J. T., Henderson, M. T., Desai, M., Wactawski-Wende, J., Stefanick, M. L., Tang, J. Y., Alcohol consumption and risk of melanoma and non-melanoma skin cancer in the Women's Health Initiative, Cancer Causes Control, 2014. 25(1): p. 1-10., https://www.ncbi.nlm.nih.gov/pubmed/24173533

383. Jiang, A. J., Rambhatla, P. V., Eide, M. J., Socioeconomic and lifestyle factors and melanoma: a systematic review, Br J Dermatol, 2015. 172(4): p. 885-915., https://www.ncbi.nlm.nih.gov/pubmed/25354495

384. Leitlinienprogramm Onkologie, S3 Leitlinie Aktinische Keratose und Plattenepithelkarzinom der Haut, 2019., https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Aktinische_Keratosen_und_PEK/LL_Aktinische_Keratose_und_PEK_Langversion_1.0.pdf

385. Lang, B., Balermpas, P., Bauer, A., Blum, A., Brölsch, G.,, Dirschka, T., Follmann, M., et.al. S2k-Leitlinie Basalzellkarzinom der Hau, 2018., https://www.awmf.org/uploads/tx_szleitlinien/032-021l_S2k_Basalzellkarzinom-der-Haut_2018-09_01.pdf

386. Buller, D. B., Andersen, P. A., Walkosz, B. J., Scott, M. D., Cutter, G. R., Dignan, M. B., et.al. Randomized trial testing a worksite sun protection program in an outdoor recreation industry, Health Educ Behav, 2005. 32(4): p. 514-35., https://www.ncbi.nlm.nih.gov/pubmed/16009748

387. Loescher, L. J., Emerson, J., Taylor, A., Christensen, D. H., McKinney, M., Educating preschoolers about sun safety, Am J Public Health, 1995. 85(7): p. 939-43., https://www.ncbi.nlm.nih.gov/pubmed/7604917

388. Mermelstein, R., Weeks, K., Turner, L., Cobb, J., When tailored feedback backfires: A skin cancer prevention intervention for adolescents, Cancer Research Therapy and Control, 1999. p. 8(1-2)(pp 69-79), 1999.

389. Norman, G. J., Adams, M. A., Calfas, K. J., Covin, J., Sallis, J. F., Rossi, J. S., et.al. A randomized trial of a multicomponent intervention for adolescent sun protection behaviors, Arch Pediatr Adolesc Med, 2007. 161(2): p. 146-52., https://www.ncbi.nlm.nih.gov/pubmed/17283299

390. Gallagher, R. P., Rivers, J. K., Lee, T. K., Bajdik, C. D., McLean, D. I., Coldman, A. J., Broad-spectrum sunscreen use and the development of new nevi in white children: A randomized controlled trial, JAMA, 2000. 283(22): p. 2955-60., https://www.ncbi.nlm.nih.gov/pubmed/10865273

391. de Maleissye, M. F., Beauchet, A., Saiag, P., Correa, M., Godin-Beeckmann, S., Haeffelin, M., et.al. Sunscreen use and melanocytic nevi in children: a systematic review, Pediatr Dermatol, 2013. 30(1): p. 51-9., https://www.ncbi.nlm.nih.gov/pubmed/22994908

392. Ulrich, C., Jurgensen, J. S., Degen, A., Hackethal, M., Ulrich, M., Patel, M. J., et.al. Prevention of non-melanoma skin cancer in organ transplant patients by regular use of a sunscreen: a 24 months, prospective, case-control study, Br J Dermatol, 2009. 161 Suppl 3: p. 78-84., https://www.ncbi.nlm.nih.gov/pubmed/19775361

393. Türk, T. R., Witzke, O., Zeier, M., KDIGO-Leitlinien zur Betreuung von Nierentransplantatempfängern, Der Nephrologe, 2010. 5(2): p. 94-107.

394. Schwalfenberg, G., Not enough vitamin D: Health consequences for Canadians, Canadian Family Physician, 2007. p. 53(5)(pp 841-854), 2007., https://www.ncbi.nlm.nih.gov/pubmed/17872747

395. Srikanth, V., Fryer, J., Venn, A., Blizzard, L., Newman, L., Cooley, H., et.al. The association between non-melanoma skin cancer and osteoporotic fractures--a population-based record linkage study, Osteoporos Int, 2007. 18(5): p. 687-92., https://www.ncbi.nlm.nih.gov/pubmed/17211531

396. Bonilla, C., Ness, A. R., Wills, A. K., Lawlor, D. A., Lewis, S. J., Davey Smith, G., Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children, BMC Public Health, 2014. 14: p. 597., https://www.ncbi.nlm.nih.gov/pubmed/24924479

397. Lindqvist, P. G., Epstein, E., Landin-Olsson, M., Ingvar, C., Nielsen, K., Stenbeck, M., et.al. Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort, J Intern Med, 2014. 276(1): p. 77-86., https://www.ncbi.nlm.nih.gov/pubmed/24697969

398. Lindqvist, P. G., Epstein, E., Nielsen, K., Landin-Olsson, M., Ingvar, C., Olsson, H., Avoidance of sun exposure as a risk factor for major causes of death: a competing risk analysis of the Melanoma in Southern Sweden cohort, J Intern Med, 2016. 280(4): p. 375-87., https://www.ncbi.nlm.nih.gov/pubmed/26992108

399. UV-Schutz-Bündnis, Bundesamt für Strahlenschutz, Vorbeugung gesundheitlicher Schäden durch die Sonne – Verhältnisprävention in der Stadt und auf dem Land: Grundsatzpapier des UV-Schutz-Bündnisses, Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2017. 60(10):1153–1160.:

400. van der Rhee, H. J., de Vries, E., Coebergh, J. W., Does sunlight prevent cancer? A systematic review, Eur J Cancer, 2006. 42(14): p. 2222-32., https://www.ncbi.nlm.nih.gov/pubmed/16904314

401. Tuohimaa, P., Pukkala, E., Scelo, G., Olsen, J. H., Brewster, D. H., Hemminki, K., et.al. Does solar exposure, as indicated by the non-melanoma skin cancers, protect from solid cancers: vitamin D as a possible explanation, Eur J Cancer, 2007. 43(11): p. 1701-12., https://www.ncbi.nlm.nih.gov/pubmed/17540555

402. Krause, R., Matulla-Nolte, B., Essers, M., Brown, A., Hopfenmuller, W., UV radiation and cancer prevention: what is the evidence?, Anticancer Res, 2006. 26(4A): p. 2723-7., https://www.ncbi.nlm.nih.gov/pubmed/16886683

403. Haluza, D., Simic, S., Holtge, J., Cervinka, R., Moshammer, H., Gender aspects of recreational sun-protective behavior: results of a representative, population-based survey among Austrian residents, Photodermatol Photoimmunol Photomed, 2016. 32(1): p. 11-21., https://www.ncbi.nlm.nih.gov/pubmed/26431724

404. Antonov, D., Hollunder, M., Schliemann, S., Elsner, P., Ultraviolet Exposure and Protection Behavior in the General Population: A Structured Interview Survey, Dermatology, 2016. 232(1): p. 11-6., https://www.ncbi.nlm.nih.gov/pubmed/26619287

405. Gavin, A., Boyle, R., Donnelly, D., Donnelly, C., Gordon, S., McElwee, G., et.al. Trends in skin cancer knowledge, sun protection practices and behaviours in the Northern Ireland population, Eur J Public Health, 2012. 22(3): p. 408-12., https://www.ncbi.nlm.nih.gov/pubmed/22094579

406. Ghiasvand, R., Lund, E., Edvardsen, K., Weiderpass, E., Veierod, M. B., Prevalence and trends of sunscreen use and sunburn among Norwegian women, Br J Dermatol, 2015. 172(2): p. 475-83., https://www.ncbi.nlm.nih.gov/pubmed/25279754

407. Falk, M., Faresjo, A., Faresjo, T., Sun exposure habits and health risk-related behaviours among individuals with previous history of skin cancer, Anticancer Res, 2013. 33(2): p. 631-8., https://www.ncbi.nlm.nih.gov/pubmed/23393359

408. Blashill, A. J., Safren, S. A., Skin cancer risk behaviors among US men: the role of sexual orientation, Am J Public Health, 2014. 104(9): p. 1640-1., https://www.ncbi.nlm.nih.gov/pubmed/25033138

409. Ackermann, S., Vuadens, A., Levi, F., Bulliard, J. L., Sun protective behaviour and sunburn prevalence in primary and secondary schoolchildren in western Switzerland, Swiss Med Wkly, 2016. 146: p. w14370., https://www.ncbi.nlm.nih.gov/pubmed/27878788

410. McNoe, B. M., Reeder, A. I., Adolescent sun protection at secondary school athletic sporting events - a misnomer, Aust N Z J Public Health, 2016. 40(4): p. 313-5., https://www.ncbi.nlm.nih.gov/pubmed/27028302

411. Basch, C. H., Basch, C. E., Rajan, S., Ruggles, K. V., Use of sunscreen and indoor tanning devices among a nationally representative sample of high school students, 2001-2011, Prev Chronic Dis, 2014. 11: p. E144., https://www.ncbi.nlm.nih.gov/pubmed/25144679

412. Dobbinson, S., Wakefield, M., Hill, D., Girgis, A., Aitken, J. F., Beckmann, K., et.al. Children's sun exposure and sun protection: prevalence in Australia and related parental factors, J Am Acad Dermatol, 2012. 66(6): p. 938-47., https://www.ncbi.nlm.nih.gov/pubmed/21890234

413. Dusza, S. W., Halpern, A. C., Satagopan, J. M., Oliveria, S. A., Weinstock, M. A., Scope, A., et.al. Prospective study of sunburn and sun behavior patterns during adolescence, Pediatrics, 2012. 129(2): p. 309-17., https://www.ncbi.nlm.nih.gov/pubmed/22271688

414. Reinau, D., Meier, C., Gerber, N., Hofbauer, G. F., Surber, C., Sun protective behaviour of primary and secondary school students in North-Western Switzerland, Swiss Med Wkly, 2012. 142: p. w13520., https://www.ncbi.nlm.nih.gov/pubmed/22367965

415. Tuncer Vural, A., Karatas Togral, A., Kirnap, M., Gulec, A. T., Haberal, M., Skin Cancer Risk Awareness and Sun-Protective Behavior Among Solid-Organ Transplant Recipients, Exp Clin Transplant, 2018. 16 Suppl 1(Suppl 1): p. 203-207., https://www.ncbi.nlm.nih.gov/pubmed/29528028

416. Heerfordt, I. M., Philipsen, P. A., Wulf, H. C., Sun behaviour on the beach monitored by webcam photos, Public Health, 2018. 155: p. 88-90., https://www.ncbi.nlm.nih.gov/pubmed/29328978

417. Cercato, M. C., Ramazzotti, V., Sperduti, I., Asensio-Pascual, A., Ribes, I., Guillen, C., et.al. Sun protection among Spanish beachgoers: knowledge, attitude and behaviour, J Cancer Educ, 2015. 30(1): p. 4-11., https://www.ncbi.nlm.nih.gov/pubmed/24890922

418. Diehl, K., Göring, T., Greinert, R., Breitbart, E.W., Schneider, S., Trends in Tanning Bed Use, Motivation, and Risk Awareness: Findings from four waves of the National Cancer Aid Monitoring (NCAM), International Journal of Environmental Research and Public Health, 2019. 16(20): p. 3913.

419. Schneider, S., Gorig, T., Schilling, L., Breitbart, E. W., Greinert, R., Diehl, K., German "National Cancer Aid Monitoring" 2015-2019 - study protocol and initial results, J Dtsch Dermatol Ges, 2017. 15(9): p. 895-903., https://www.ncbi.nlm.nih.gov/pubmed/28771939

420. Gambla, W. C., Fernandez, A. M., Gassman, N. R., Tan, M. C. B., Daniel, C. L., College tanning behaviors, attitudes, beliefs, and intentions: A systematic review of the literature, Prev Med, 2017. 105: p. 77-87., https://www.ncbi.nlm.nih.gov/pubmed/28867504

421. Petersen, B., Triguero-Mas, M., Maier, B., Thieden, E., Philipsen, P. A., Heydenreich, J., et.al. Sun behaviour and personal UVR exposure among Europeans on short term holidays, J Photochem Photobiol B, 2015. 151: p. 264-9., https://www.ncbi.nlm.nih.gov/pubmed/26332747

422. Borner, F., Greinert, R., Schutz, H., Wiedemann, P., [UV risk perception by the general public: results of a representative questionnaire in Germany], Gesundheitswesen, 2010. 72(12): p. e89-97., https://www.ncbi.nlm.nih.gov/pubmed/20049688

423. Eichhorn, C., Seibold, C., Loss, J., Steinmann, A., Nagel, E., [Knowledge about UV-radiation and sun protection: survey of adolescents and young adults in Bavaria], Hautarzt, 2008. 59(10): p. 821-7., https://www.ncbi.nlm.nih.gov/pubmed/18810371

424. Rutten, L. F., Hesse, B. W., Moser, R. P., McCaul, K. D., Rothman, A. J., Public perceptions of cancer prevention, screening, and survival: comparison with state-of-science evidence for colon, skin, and lung cancer, J Cancer Educ, 2009. 24(1): p. 40-8., https://www.ncbi.nlm.nih.gov/pubmed/19259865

425. Hajdarevic, S., Hvidberg, L., Lin, Y., Donnelly, C., Gavin, A., Lagerlund, M., et.al. Awareness of sunburn in childhood, use of sunbeds and change of moles in Denmark, Northern Ireland, Norway and Sweden, Eur J Public Health, 2016. 26(1): p. 29-35., https://www.ncbi.nlm.nih.gov/pubmed/26082445

426. Boynton, A., Oxlad, M., Melanoma and its relationship with solarium use: health knowledge, attitudes and behaviour of young women, J Health Psychol, 2011. 16(6): p. 969-79., https://www.ncbi.nlm.nih.gov/pubmed/21444729

427. Gordon, M., Rodriguez, V. M., Shuk, E., Schoenhammer, M., Halpern, A. C., Geller, A. C., et.al. Teen Daughters and Their Mothers in Conversation: Identifying Opportunities for Enhancing Awareness of Risky Tanning Behaviors, J Adolesc Health, 2016. 58(5): p. 579-81., https://www.ncbi.nlm.nih.gov/pubmed/27107911

428. Keeney, S., McKenna, H., Fleming, P., McIlfatrick, S., Attitudes, knowledge and behaviours with regard to skin cancer: a literature review, Eur J Oncol Nurs, 2009. 13(1): p. 29-35., https://www.ncbi.nlm.nih.gov/pubmed/19153059

429. Butler, D. P., Lloyd-Lavery, A., Archer, C. M., Turner, R., Awareness of and attitudes towards skin-cancer prevention: a survey of patients in the UK presenting to their general practice, Clin Exp Dermatol, 2013. 38(4): p. 338-43., https://www.ncbi.nlm.nih.gov/pubmed/23530554

430. Kyle, R. G., Nicoll, A., Forbat, L., Hubbard, G., Adolescents' awareness of cancer risk factors and associations with health-related behaviours, Health Educ Res, 2013. 28(5): p. 816-27., https://www.ncbi.nlm.nih.gov/pubmed/23648385

431. Gefeller, O., Uter, W., Pfahlberg, A. B., Long-term development of parental knowledge about skin cancer risks in Germany: Has it changed for the better?, Prev Med, 2016. 89: p. 31-36., https://www.ncbi.nlm.nih.gov/pubmed/27211108

432. Hamilton, K., Cleary, C., White, K. M., Hawkes, A. L., Keeping kids sun safe: exploring parents' beliefs about their young child's sun-protective behaviours, Psychooncology, 2016. 25(2): p. 158-63., https://www.ncbi.nlm.nih.gov/pubmed/26101815

433. Day, A. K., Wilson, C. J., Hutchinson, A. D., Roberts, R. M., The role of skin cancer knowledge in sun-related behaviours: a systematic review, J Health Psychol, 2014. 19(9): p. 1143-62., https://www.ncbi.nlm.nih.gov/pubmed/23682066

434. Ruppert, L., Koster, B., Siegert, A. M., Cop, C., Boyers, L., Karimkhani, C., et.al. YouTube as a source of health information: Analysis of sun protection and skin cancer prevention related issues, Dermatol Online J, 2017. 23(1):, https://www.ncbi.nlm.nih.gov/pubmed/28329465

435. Buller, M. K., Kane, I. L., Martin, R. C., Giese, A. J., Cutter, G. R., Saba, L. M., et.al. Randomized trial evaluating computer-based sun safety education for children in elementary school, Journal of cancer education : the official journal of the American Association for Cancer Education, 2008. 23(2): p. 74-9.

436. Bränström, R., Ullén, H., Brandberg, Y., A randomised population-based intervention to examine the effects of the ultraviolet index on tanning behaviour, European Journal of Cancer, 2003. 39(7): p. 968-974.

437. Gritz, E. R., Tripp, M. K., James, A. S., Harrist, R. B., Mueller, N. H., Chamberlain, R. M., et.al. Effects of a preschool staff intervention on children's sun protection: outcomes of sun protection is fun!, Health Educ Behav, 2007. 34(4): p. 562-77., https://www.ncbi.nlm.nih.gov/pubmed/16740505

438. Bastuji-Garin, S., Grob, J. J., Grognard, C., Grosjean, F., Guillaume, J. C., Melanoma prevention: evaluation of a health education campaign for primary schools, Arch Dermatol, 1999. 135(8): p. 936-40., https://www.ncbi.nlm.nih.gov/pubmed/10456342

439. Reding, D. J., Fischer, V., Gunderson, P., Lappe, K., Anderson, H., Calvert, G., Teens teach skin cancer prevention, J Rural Health, 1996. 12(4 Suppl): p. 265-72., https://www.ncbi.nlm.nih.gov/pubmed/10162857

440. Bundeszentrale für politische Bildung, Medienkompetenz. Herausforderung für Politik, politische Bildung und Medienbildung., 2017., http://www.bpb.de/system/files/dokument_pdf/10111_Medienkompetenz_ba.pdf

441. Buller, D. B., Reynolds, K. D., Berteletti, J., Massie, K., Ashley, J., Buller, M. K., et.al. Accuracy of Principal and Teacher Knowledge of School District Policies on Sun Protection in California Elementary Schools, Prev Chronic Dis, 2018. 15: p. E07., https://www.ncbi.nlm.nih.gov/pubmed/29346065

442. Buller, D. B., Borland, R., Skin Cancer Prevention for Children: A Critical Review, Health Education & Behavior, 1999. 26(3): p. 317-343.

443. Dietrich, A. J., Olson, A. L., Sox, C. H., Tosteson, T. D., Grant-Petersson, J., Persistent increase in children's sun protection in a randomized controlled community trial, Prev Med, 2000. 31(5): p. 569-74., https://www.ncbi.nlm.nih.gov/pubmed/11071838

444. Hart, K. M., Demarco, R. F., Primary prevention of skin cancer in children and adolescents: a review of the literature, J Pediatr Oncol Nurs, 2008. 25(2): p. 67-78., https://www.ncbi.nlm.nih.gov/pubmed/18272782

445. Weinstock, M. A., Rossi, J. S., Redding, C. A., Maddock, J. E., Randomized controlled community trial of the efficacy of a multicomponent stage-matched intervention to increase sun protection among beachgoers, Prev Med, 2002. 35(6): p. 584-92., https://www.ncbi.nlm.nih.gov/pubmed/12460526

446. Milne, E., English, D. R., Cross, D., Corti, B., Costa, C., Johnston, R., Evaluation of an intervention to reduce sun exposure in children: design and baseline results, Am J Epidemiol, 1999. 150(2): p. 164-73., https://www.ncbi.nlm.nih.gov/pubmed/10412961

447. Bauer, J., Buttner, P., Wiecker, T. S., Luther, H., Garbe, C., Interventional study in 1,232 young German children to prevent the development of melanocytic nevi failed to change sun exposure and sun protective behavior, Int J Cancer, 2005. 116(5): p. 755-61., https://www.ncbi.nlm.nih.gov/pubmed/15849749

448. Mayer, J. A., Slymen, D. J., Eckhardt, L., Johnston, M. R., Elder, J. P., Sallis, J. F., et.al. Reducing ultraviolet radiation exposure in children, Prev Med, 1997. 26(4): p. 516-22., https://www.ncbi.nlm.nih.gov/pubmed/9245674

449. Garside, R., Pearson, M., Moxham, T., What influences the uptake of information to prevent skin cancer? A systematic review and synthesis of qualitative research, Health Educ Res, 2010. 25(1): p. 162-82., https://www.ncbi.nlm.nih.gov/pubmed/19858077

450. Glanz, K., Schoenfeld, E. R., Steffen, A., A randomized trial of tailored skin cancer prevention messages for adults: Project SCAPE, American journal of public health, 2010. 100(4): p. 735-41.

451. Loescher, L. J., Buller, M. K., Buller, D. B., Emerson, J., Taylor, A. M., Public education projects in skin cancer. The evolution of skin cancer prevention education for children at a comprehensive cancer center, Cancer, 1995. 75(2 Suppl): p. 651-6., https://www.ncbi.nlm.nih.gov/pubmed/7804990

452. White, K. M., Starfelt, L. C., Young, R. M., Hawkes, A. L., Cleary, C., Leske, S., et.al. A randomised controlled trial of an online theory-based intervention to improve adult Australians' sun-protective behaviours, Prev Med, 2015. 72: p. 19-22., https://www.ncbi.nlm.nih.gov/pubmed/25572618

453. Adams, M. A., Norman, G. J., Hovell, M. F., Sallis, J. F., Patrick, K., Reconceptualizing decisional balance in an adolescent sun protection intervention: mediating effects and theoretical interpretations, Health Psychol, 2009. 28(2): p. 217-25.

454. Hornung, R. L., Lennon, P. A., Garrett, J. M., DeVellis, R. F., Weinberg, P. D., Strecher, V. J., Interactive computer technology for skin cancer prevention targeting children, Am J Prev Med, 2000. 18(1): p. 69-76.

455. Gritz, E. R., Tripp, M. K., James, A. S., Carvajal, S. C., Harrist, R. B., Mueller, N. H., et.al. An intervention for parents to promote preschool children's sun protection: effects of Sun Protection is Fun!, Preventive medicine, 2005. 41(2): p. 357-66.

456. Kiekbusch, S., Hannich, H. J., Isacsson, A., Johannisson, A., Lindholm, L. H., Sager, E., et.al. Impact of a cancer education multimedia device on public knowledge, attitudes, and behaviors: a controlled intervention study in Southern Sweden, Journal of cancer education : the official journal of the American Association for Cancer Education, 2000. 15(4): p. 232-6.

457. Boer, H., Ter Huurne, E., Taal, E., Effects of pictures and textual arguments in sun protection public service announcements, Cancer detection and prevention, 2006. 30(5): p. 432-8.

458. Walkosz, B., Voeks, J., Andersen, P., Scott, M., Buller, D., Cutter, G., et.al. Randomized trial on sun safety education at ski and snowboard schools in western North America, Pediatr Dermatol, 2007. 24(3): p. 222-9.

459. Glazebrook, C., Garrud, P., Avery, A., Coupland, C., Williams, H., Impact of a multimedia intervention "Skinsafe" on patients' knowledge and protective behaviors, Preventive medicine, 2006. 42(6): p. 449-54.

460. Hanrahan, P. F., Hersey, P., Watson, A. B., Callaghan, T. M., The effect of an educational brochure on knowledge and early detection of melanoma, Aust J Public Health, 1995. 19(3): p. 270-4.

461. Idriss, N. Z., Alikhan, A., Baba, K., Armstrong, A. W., Online, video-based patient education improves melanoma awareness: a randomized controlled trial, Telemed J E Health, 2009. 15(10): p. 992-7.

462. Girardi, S., Gaudy, C., Gouvernet, J., Teston, J., Richard, M. A., Grob, J. J., Superiority of a cognitive education with photographs over ABCD criteria in the education of the general population to the early detection of melanoma: a randomized study, International journal of cancer. Journal international du cancer, 2006. 118(9): p. 2276-80.

463. Janda, M., Baade, P. D., Youl, P. H., Aitken, J. F., Whiteman, D. C., Gordon, L., et.al. The skin awareness study: promoting thorough skin self-examination for skin cancer among men 50 years or older, Contemporary clinical trials, 2010. 31(1): p. 119-30.

464. Crane, L. A., Asdigian, N. L., Baron, A. E., Aalborg, J., Marcus, A. C., Mokrohisky, S. T., et.al. Mailed intervention to promote sun protection of children: a randomized controlled trial, Am J Prev Med, 2012. 43(4): p. 399-410., https://www.ncbi.nlm.nih.gov/pubmed/22992358

465. Glanz, K., Steffen, A. D., Schoenfeld, E., Tappe, K. A., Randomized trial of tailored skin cancer prevention for children: the Project SCAPE family study, J Health Commun, 2013. 18(11): p. 1368-83., https://www.ncbi.nlm.nih.gov/pubmed/23806094

466. Glanz, K., Volpicelli, K., Jepson, C., Ming, M. E., Schuchter, L. M., Armstrong, K., Effects of tailored risk communications for skin cancer prevention and detection: the PennSCAPE randomized trial, Cancer Epidemiol Biomarkers Prev, 2015. 24(2): p. 415-21., https://www.ncbi.nlm.nih.gov/pubmed/25432953

467. Heckman, C. J., Darlow, S. D., Ritterband, L. M., Handorf, E. A., Manne, S. L., Efficacy of an Intervention to Alter Skin Cancer Risk Behaviors in Young Adults, Am J Prev Med, 2016. 51(1): p. 1-11., https://www.ncbi.nlm.nih.gov/pubmed/26810358

468. Finch, Linda, Janda, Monika, Loescher, Lois J., Hacker, Elke, Can skin cancer prevention be improved through mobile technology interventions? A systematic review, Preventive Medicine: An International Journal Devoted to Practice and Theory, 2016. 90: p. 121-132., http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc13a&AN=2016-43790-019, http://sfx.gbv.de/sfx_subhh?sid=OVID:psycdb&id=pmid:&id=doi:10.1016%2Fj.ypmed.2016.06.037&issn=0091-7435&isbn=&volume=90&issue=&spage=121&pages=121-132&date=2016&title=Preventive+Medicine%3A+An+International+Journal+Devoted+to+Practice+and+Theory&atitle=Can+skin+cancer+prevention+be+improved+through+mobile+technology+interventions%3F+A+systematic+review.&aulast=Finch

469. Austoker, J., Bankhead, C., Forbes, L. J., Atkins, L., Martin, F., Robb, K., et.al. Interventions to promote cancer awareness and early presentation: systematic review, Br J Cancer, 2009. 101 Suppl 2: p. S31-9., https://www.ncbi.nlm.nih.gov/pubmed/19956160

470. Real, K., Rimal, R. N., Friends talk to friends about drinking: exploring the role of peer communication in the theory of normative social behavior, Health Commun, 2007. 22(2): p. 169-80.

471. Geulen, D, Sozialisation, in Lehrbuch der Soziologie, Joas, H , Editor. 2007, Campus Verlag: Frankfurt, New York. 3: p. 137-159.

472. Kahn, J. A., Huang, B., Ding, L., Geller, A., Frazier, A. L., Impact of maternal communication about skin, cervical, and lung cancer prevention on adolescent prevention behaviors, J Adolesc Health, 2011. 49(1): p. 93-6., https://www.ncbi.nlm.nih.gov/pubmed/21700165

473. Hillhouse, J., Turrisi, R., Scaglione, N. M., Cleveland, M. J., Baker, K., Florence, L. C., A Web-Based Intervention to Reduce Indoor Tanning Motivations in Adolescents: a Randomized Controlled Trial, Prev Sci, 2017. 18(2): p. 131-140., https://www.ncbi.nlm.nih.gov/pubmed/27549602

474. Falzone, A. E., Brindis, C. D., Chren, M. M., Junn, A., Pagoto, S., Wehner, M., et.al. Teens, Tweets, and Tanning Beds: Rethinking the Use of Social Media for Skin Cancer Prevention, Am J Prev Med, 2017. 53(3S1): p. S86-S94., https://www.ncbi.nlm.nih.gov/pubmed/28818251

475. Hill, S. E., Durante, K. M., Courtship, competition, and the pursuit of attractiveness: mating goals facilitate health-related risk taking and strategic risk suppression in women, Pers Soc Psychol Bull, 2011. 37(3): p. 383-94., https://www.ncbi.nlm.nih.gov/pubmed/21252381

476. Reifegerste, Doreen, Rössler, Patrick, Soziale Appelle in der Gesundheitskommunikation. Motivkategorien als Grundlage für die theoretische Integration und die Systematisierung empirischer Befunde, Medien & Kommunikationswissenschaft, 2014. 62(4): p. 606-634., https://doi.org/10.5771/1615-634x-2014-4-606

477. Williams, A. L., Grogan, S., Clark-Carter, D., Buckley, E., Appearance-based interventions to reduce ultraviolet exposure and/or increase sun protection intentions and behaviours: a systematic review and meta-analyses, Br J Health Psychol, 2013. 18(1): p. 182-217., https://www.ncbi.nlm.nih.gov/pubmed/22989352

478. Robinson, J. K., Turrisi, R., Stapleton, J., Efficacy of a partner assistance intervention designed to increase skin self-examination performance, Arch Dermatol, 2007. 143(1): p. 37-41.

479. Robinson, J. K., Turrisi, R., Stapleton, J., Examination of mediating variables in a partner assistance intervention designed to increase performance of skin self-examination, J Am Acad Dermatol, 2007. 56(3): p. 391-7., https://www.ncbi.nlm.nih.gov/pubmed/17147966

480. Heckman, C. J., Zhu, F., Manne, S. L., Kloss, J. D., Collins, B. N., Bass, S. B., et.al. Process and outcomes of a skin protection intervention for young adults, J Health Psychol, 2013. 18(4): p. 561-73., https://www.ncbi.nlm.nih.gov/pubmed/22843632

481. Blashill, A. J., Rooney, B. M., Luberto, C. M., Gonzales, M. th, Grogan, S., A brief facial morphing intervention to reduce skin cancer risk behaviors: Results from a randomized controlled trial, Body Image, 2018. 25: p. 177-185., https://www.ncbi.nlm.nih.gov/pubmed/29698824

482. Hollands, G. J., Hankins, M., Marteau, T. M., Visual feedback of individuals' medical imaging results for changing health behaviourJohn Wiley & Sons, Ltd, Cochrane Database of Systematic Reviews, 2010., http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007434/frame.html

483. Hillhouse, J., Turrisi, R., Stapleton, J., Robinson, J., A randomized controlled trial of an appearance-focused intervention to prevent skin cancer, Cancer, 2008. 113(11): p. 3257-66., https://www.ncbi.nlm.nih.gov/pubmed/18937268

484. Hillhouse, J., Turrisi, R., Stapleton, J., Robinson, J., Effect of seasonal affective disorder and pathological tanning motives on efficacy of an appearance-focused intervention to prevent skin cancer, Arch Dermatol, 2010. 146(5): p. 485-91., https://www.ncbi.nlm.nih.gov/pubmed/20479295

485. Mahler, H. I., Kulik, J. A., Harrell, J., Correa, A., Gibbons, F. X., Gerrard, M., Effects of UV photographs, photoaging information, and use of sunless tanning lotion on sun protection behaviors, Arch Dermatol, 2005. 141(3): p. 373-80., https://www.ncbi.nlm.nih.gov/pubmed/15781679

486. Stock, M. L., Gerrard, M., Gibbons, F. X., Dykstra, J. L., Weng, C. Y., Mahler, H. I., et.al. Sun protection intervention for highway workers: long-term efficacy of UV photography and skin cancer information on men's protective cognitions and behavior, Ann Behav Med, 2009. 38(3): p. 225-36., https://www.ncbi.nlm.nih.gov/pubmed/20049658

487. Robinson, J. K., Turrisi, R., Stapleton, J., Efficacy of a partner assistance intervention designed to increase skin self-examination performance, Arch Dermatol, 2007. 143(1): p. 37-41., https://www.ncbi.nlm.nih.gov/pubmed/17224540

488. Rosenbrock, R., Hartung, S., Public Health Action Cycle / Gesundheitspolitischer Aktionszyklus, in Leitbegriffe der Gesundheitsförderung, Bundeszentrale für Gesundheitliche Auflärung (BZgA) , Editor. 2015, Bundeszentrale für gesundheitliche Aufklärung (BZgA).

489. Weltgesundheitsorganisation, Ottawa-Charta zur Gesundheitsförderung, 1986.

490. Crane, L. A., Deas, A., Mokrohisky, S. T., Ehrsam, G., Jones, R. H., Dellavalle, R., et.al. A randomized intervention study of sun protection promotion in well-child care, Prev Med, 2006. 42(3): p. 162-70., https://www.ncbi.nlm.nih.gov/pubmed/16376977

491. English, D. R., Milne, E., Jacoby, P., Giles-Corti, B., Cross, D., Johnston, R., The effect of a school-based sun protection intervention on the development of melanocytic nevi in children: 6-year follow-up, Cancer Epidemiol Biomarkers Prev, 2005. 14(4): p. 977-80., https://www.ncbi.nlm.nih.gov/pubmed/15824173

492. Milne, E., English, D. R., Johnston, R., Cross, D., Borland, R., Costa, C., et.al. Improved sun protection behaviour in children after two years of the Kidskin intervention, Aust N Z J Public Health, 2000. 24(5): p. 481-7., https://www.ncbi.nlm.nih.gov/pubmed/11109684

493. Milne, E., Johnston, R., Cross, D., Giles-Corti, B., English, D. R., Effect of a school-based sun-protection intervention on the development of melanocytic nevi in children, Am J Epidemiol, 2002. 155(8): p. 739-45., https://www.ncbi.nlm.nih.gov/pubmed/11943692

494. Naldi, L., Chatenoud, L., Bertuccio, P., Zinetti, C., Di Landro, A., Scotti, L., et.al. Improving sun-protection behavior among children: results of a cluster-randomized trial in Italian elementary schools. The "SoleSi SoleNo-GISED" Project, J Invest Dermatol, 2007. 127(8): p. 1871-7., https://www.ncbi.nlm.nih.gov/pubmed/17460732

495. Rat, C., Quereux, G., Riviere, C., Clouet, S., Senand, R., Volteau, C., et.al. Targeted melanoma prevention intervention: a cluster randomized controlled trial, Ann Fam Med, 2014. 12(1): p. 21-8., https://www.ncbi.nlm.nih.gov/pubmed/24445100

496. Falk, M., Magnusson, H., Sun protection advice mediated by the general practitioner: an effective way to achieve long-term change of behaviour and attitudes related to sun exposure?, Scand J Prim Health Care, 2011. 29(3): p. 135-43., https://www.ncbi.nlm.nih.gov/pubmed/21682578

497. Mayer, J. A., Slymen, D. J., Eckhardt, L., Rosenberg, C., Stepanski, B. M., Creech, L., et.al. Skin cancer prevention counseling by pharmacists: specific outcomes of an intervention trial, Cancer Detect Prev, 1998. 22(4): p. 367-75., https://www.ncbi.nlm.nih.gov/pubmed/9674880

498. Livingston, P. M., White, V., Hayman, J., Dobbinson, S., Australian adolescents' sun protection behavior: who are we kidding?, Prev Med, 2007. 44(6): p. 508-12., https://www.ncbi.nlm.nih.gov/pubmed/17400286

499. Shibuya, K., Ciecierski, C., Guindon, E., Bettcher, D. W., Evans, D. B., Murray, C. J., et.al. WHO Framework Convention on Tobacco Control: development of an evidence based global public health treaty, BMJ, 2003. 327(7407): p. 154-7., https://www.ncbi.nlm.nih.gov/pubmed/12869461

500. Dobbinson, S. J., White, V., Wakefield, M. A., Jamsen, K. M., White, V., Livingston, P. M., et.al. Adolescents' use of purpose built shade in secondary schools: cluster randomised controlled trial, BMJ, 2009. 338(feb17 1): p. b95., https://www.ncbi.nlm.nih.gov/pubmed/19223344

501. Buller, M. K., Goldberg, G., Buller, D. B., Sun Smart Day: a pilot program for photoprotection education, Pediatr Dermatol, 1997. 14(4): p. 257-63., https://www.ncbi.nlm.nih.gov/pubmed/9263304

502. Quereux, G., Nguyen, J. M., Volteau, C., Dreno, B., Prospective trial on a school-based skin cancer prevention project, Eur J Cancer Prev, 2009. 18(2): p. 133-44., https://www.ncbi.nlm.nih.gov/pubmed/19337061

503. Allinson, Sarah, Asmuss, Monika, Baldermann, Cornelia, Bentzen, Joan, Buller, David, Gerber, Nathalie, et.al. Validity and Use of the UV Index: Report from the UVI Working Group, Schloss Hohenkammer, Germany, 5–7 December 2011, Health Physics, 2012. 103(3): p. 301-306 10.1097/HP0b013e31825b581e., http://journals.lww.com/health-physics/Fulltext/2012/09000/Validity_and_Use_of_the_UV_Index___Report_from_the.9.aspx

504. Bonfadelli, H., Friemel, T. N., Kommunikationskampagnen im Gesundheitsbereich. Grundlagen und AnwendungenUVK-Verl.-Ges., 2010.

505. Klimmt, C., Maurer, M. & Baumann, E., Prozessevaluation der Kampagnenfortsetzung 2011-2012 „Runter vom Gas!“ (ID - 503, 2014.

506. Reifegerste, D., Baumann, E., Vielfalt und Herausforderungen der Evidenzbasierung in der strategischen Gesundheitskommunikation, in Evidenzbasierte und evidenzinformierte Gesundheitskommunikation, 2018, Nomos: Baden-Baden. p. 73-83.

507. Rossmann, C., Strategic Health Communication: Theory- and Evidence-Based Campaign Development, in Routledge handbook of strategic communication, Holtzhausen, D. R. , Editor. 2015, Routledge: New York u.a.. p. 409–423.

508. Schnabel, P, Boedeker, M, GesundheitskommunikationBeltz Juventa, 2012.

509. Valente, T W, Evaluating Communication CampaignsSage Publications, Inc., Public Communication Campaigns, 2001. 3: p. 105-124.

510. Ajzen, I., The Theory of Planned Behavior, Organizational Behavior and Human Decision Processes, 1991. 50(2): p. 179-211.

511. Janz, N. K., Becker, M. H., The Health Belief Model: a decade later, Health Educ Q, 1984. 11(1): p. 1-47., https://www.ncbi.nlm.nih.gov/pubmed/6392204

512. Prochaska, J. O., Velicer, W. F., Redding, C., Rossi, J. S., Goldstein, M., DePue, J., et.al. Stage-based expert systems to guide a population of primary care patients to quit smoking, eat healthier, prevent skin cancer, and receive regular mammograms, Prev Med, 2005. 41(2): p. 406-16., https://www.ncbi.nlm.nih.gov/pubmed/15896835

513. Del Mar, C. B., Green, A. C., Battistutta, D., Do public media campaigns designed to increase skin cancer awareness result in increased skin excision rates?, Aust N Z J Public Health, 1997. 21(7): p. 751-4., https://www.ncbi.nlm.nih.gov/pubmed/9489194

514. Oivanen, T., Kojo, K., Pylkkanen, L., Holli, K., Auvinen, A., Early detection of skin cancer as public health policy: comparison of campaign and routine activity, Prev Med, 2008. 46(2): p. 160-5., https://www.ncbi.nlm.nih.gov/pubmed/17919714

515. Intergovernmental Panel on Climate Change (IPCC), Fünfter Sachstandsbericht, Teilbericht 1 (Wissenschaftliche Grundlagen). Kernbotschaften (deutsche Zusammenfassung)., 2014.

516. European Environment Agency (EEA), Climate change, impacts and vulnerability in Europe 2016. An indicator-based report, 2017., https://www.eea.europa.eu/publications/climate-change-impacts-and-vulnerability-2016

517. Kyselý, Jan, Temporal fluctuations in heat waves at Prague-Klementinum, the Czech Republic, from 1901-97, and their relationships to atmospheric circulation, International Journal of Climatology, 2002. 22(1): p. 33-50.

518. Coumou, Dim, Robinson, Alexander, Historic and future increase in the global land area affected by monthly heat extremes, Environmental Research Letters, 2013. 8(3): p. 34018-6.

519. Schar, C., Jendritzky, G., Climate change: hot news from summer 2003, Nature, 2004. 432(7017): p. 559-60., https://www.ncbi.nlm.nih.gov/pubmed/15577890

520. Seneviratne, Sonia I., Donat, Markus G., Mueller, Brigitte, Alexander, Lisa V., No pause in the increase of hot temperature extremes, Nature Climate Change, 2014. 4(3): p. 161-163., https://www.nature.com/articles/nclimate2145#supplementary-information

521. Intergovernmental Panel on Climate Change (IPCC), Managing the risks of extreme events and disasters to advance climate change adaptation: special report of the Intergovernmental Panel on Climate Change, 2012.

522. Intergovernmental Panel on Climate Change (IPCC), Summary for Policymakers, 2013.

523. Coumou, Dim, Robinson, Alexander, Rahmstorf, Stefan, Global increase in record-breaking monthly-mean temperatures, Climatic Change, 2013. 118(3-4): p. 771-782., https://doi.org/10.1007/s10584-012-0668-1

524. Kandarr, J., Reckert, H., Mücke, G., Anpassung an die gesundheitlichen Risiken des Klimawandels als Aufgabe des umweltbezogenen Gesundheitsschutzes. Analyse einer bundesweiten Recherche und Erhebung des Umweltbundesamtes, Bundesgesundheitsblatt, Springer-Verlag Berlin Heidelberg, 2014.

525. Bais, A. F., Lucas, R. M., Bornman, J. F., Williamson, C. E., Sulzberger, B., Austin, A. T., et.al. Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017, Photochem Photobiol Sci, 2018. 17(2): p. 127-179., https://www.ncbi.nlm.nih.gov/pubmed/29404558

526. Norris, J. R., Allen, R. J., Evan, A. T., Zelinka, M. D., O'Dell, C. W., Klein, S. A., Evidence for climate change in the satellite cloud record, Nature, 2016. 536(7614): p. 72-5., https://www.ncbi.nlm.nih.gov/pubmed/27398619

527. Bais, A. F., Bernhard, G., McKenzie, R. L., Aucamp, P. J., Young, P. J., Ilyas, M., et.al. Ozone-climate interactions and effects on solar ultraviolet radiation, Photochem Photobiol Sci, 2019. 18(3): p. 602-640., https://www.ncbi.nlm.nih.gov/pubmed/30810565

528. Baldermann, C., Lorenz, Sebastian, UV-Strahlung in Deutschland: Einflüsse des Ozonabbaus und des Klimawandels sowie Maßnahmen zum Schutz der Bevölkerung, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2019. 62(5): p. 639-645.

529. Seckmeyer, G., Die genaue Messung und Simulation der solaren UV-Strahlung.Seiler, M., 1999.

530. Seckmeyer, G., Thiel, S., Blumthaler, M., Fabian, P., Gerber, S., Gugg-Helminger, A., et.al. Intercomparison of spectral-UV-radiation measurement systems, Appl Opt, 1994. 33(33): p. 7805-12., https://www.ncbi.nlm.nih.gov/pubmed/20962993

531. Baumann, S., Elsner, C., de Graaf, D., Hoffmann, G., Martens, K., Noack, C., et.al. 1987 – 2017: 30 Jahre Montrealer Protokoll. Vom Ausstieg aus den FCKW zum Ausstieg aus teilfluorierten Kohlenwasserstoffen, 2017.

532. Bais, A. F., McKenzie, R. L., Bernhard, G., Aucamp, P. J., Ilyas, M., Madronich, S., et.al. Ozone depletion and climate change: impacts on UV radiation, Photochem Photobiol Sci, 2015. 14(1): p. 19-52., https://www.ncbi.nlm.nih.gov/pubmed/25380284

533. Parsons, K., Human Thermal Environments: The Effects of Hot, Moderate, and Cold Environments on Human Health, Comfort and Performance, Second EditionCRC Press, 2002.

534. Menne, B., Matthies, F., Improving public health responses to extreme weather/heat-waves: EuroHEATWorld Health Organisation, 2009.

535. Zacharias, S., Koppe, C., Einfluss des Klimawandels auf die Biotropie des Wetters und die Gesundheit bzw. die Leistungsfähigkeit der Bevölkerung in DeutschlandDeutscher Wetterdienst, Umweltforschungsplan des Bundesministeriums für Umwelt, Naturschutz, Bau und Reaktorsicherheit, 2015.

536. Augustin, J., Kis, A., Sorbe, C., Schafer, I., Augustin, M., Epidemiology of skin cancer in the German population: impact of socioeconomic and geographic factors, J Eur Acad Dermatol Venereol, 2018. 32(11): p. 1906-1913., https://www.ncbi.nlm.nih.gov/pubmed/29633375

537. Augustin, J., Sauerborn, R., Burkart, K., Endlicher, W., Jochner, S., Koppe, C., et.al. Klimawandel in DeutschlandSpringer Verlag, 2017.

538. Martens, W. J., Climate change, thermal stress and mortality changes, Soc Sci Med, 1998. 46(3): p. 331-44., https://www.ncbi.nlm.nih.gov/pubmed/9460815

539. Michelozzi, P., Accetta, G., De Sario, M., D'Ippoliti, D., Marino, C., Baccini, M., et.al. High temperature and hospitalizations for cardiovascular and respiratory causes in 12 European cities, Am J Respir Crit Care Med, 2009. 179(5): p. 383-9., https://www.ncbi.nlm.nih.gov/pubmed/19060232

540. Scherber, Katharina, Endlicher, Wilfried, Langner, Marcel, Klimawandel und Gesundheit in Berlin-Brandenburg, in Klimawandel und Gesundheit, 2013. p. 25-38.

541. Scherber, K., Langner, M., Endlicher, W., Spatial analysis of hospital admissions for respiratory diseases during summer months in Berlin taking bioclimatic and socio-economic aspects into account, Erde, 2013. 144: p. 217-237.

542. Koppe, C., Sari Kovats, R., Menne, B., Jendritzky, G., Organization, World Health, Europe, Regional Office for, Heat-waves : risks and responses, 2004.

543. van der Leun, J. C., Piacentini, R. D., de Gruijl, F. R., Climate change and human skin cancer, Photochem Photobiol Sci, 2008. 7(6): p. 730-3., https://www.ncbi.nlm.nih.gov/pubmed/18528559

544. Michal Freedman, D., Kitahara, C. M., Linet, M. S., Alexander, B. H., Neta, G., Little, M. P., et.al. Ambient temperature and risk of first primary basal cell carcinoma: A nationwide United States cohort study, J Photochem Photobiol B, 2015. 148: p. 284-289., https://www.ncbi.nlm.nih.gov/pubmed/25996074

545. Bouchama, A., Dehbi, M., Mohamed, G., Matthies, F., Shoukri, M., Menne, B., Prognostic factors in heat wave related deaths: a meta-analysis, Arch Intern Med, 2007. 167(20): p. 2170-6., https://www.ncbi.nlm.nih.gov/pubmed/17698676

546. D'Ippoliti, D., Michelozzi, P., Marino, C., de'Donato, F., Menne, B., Katsouyanni, K., et.al. The impact of heat waves on mortality in 9 European cities: results from the EuroHEAT project, Environ Health, 2010. 9: p. 37., https://www.ncbi.nlm.nih.gov/pubmed/20637065

547. Eis, Dieter, Helm, Dieter, Laußmann, Detlef, Stark, Klaus, Klimawandel und Gesundheit - ein SachstandsberichtRobert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung, 2011.

548. Koppe, C., Gesundheitsrelevante Bewertungvon thermischer Belastungunter Berücksichtigung der kurzfristigen Anpassungder Bevölkerungan die lokalen WitterungsverhältnisseInaugural-Dissertation zurErlangung der Doktorwürdeder Fakultät für Forst- und Umweltwissenschaften derAlbert-Ludwigs-UniversitätFreiburg i. Brsg., 2005.

549. Heudorf, U., Meyer, C., [Health effects of extreme heat--an example of the heat wave and mortality in Frankfurt am Main in August 2003], Gesundheitswesen, 2005. 67(5): p. 369-74., https://www.ncbi.nlm.nih.gov/pubmed/15918125

550. Schneider, A., Breitner, S., Wolf, K., Hampel, R., Peters, A., Wichmann, H.E., Ursachenspezifische Mortalität, Herzinfarkt und das Auftreten von Beschwerden bei Herzinfarktüberlebenden in Abhängigkeit von der Lufttemperatur in Bayern (MOHIT)Helmholtz Zentrum München – Deutsches Forschungszentrum für Gesundheit und Umwelt. Institut für Epidemiologie, 2009.

551. Muthers, S, aschewski, G, Matzarakis, A, The Summers 2003 and 2015 in South-West Germany: HeatWaves and Heat-Related Mortality in the Context of Climate Change, Atmosphere, 2017. 8: p. 224.

552. Hoffmann, B., Hertel, S., Boes, T., Weiland, D., Jockel, K. H., Increased cause-specific mortality associated with 2003 heat wave in Essen, Germany, J Toxicol Environ Health A, 2008. 71(11-12): p. 759-65., https://www.ncbi.nlm.nih.gov/pubmed/18569574

553. Gabriel, K. M., Endlicher, W. R., Urban and rural mortality rates during heat waves in Berlin and Brandenburg, Germany, Environ Pollut, 2011. 159(8-9): p. 2044-50., https://www.ncbi.nlm.nih.gov/pubmed/21295389

554. Burkart, K., Canario, P., Breitner, S., Schneider, A., Scherber, K., Andrade, H., et.al. Interactive short-term effects of equivalent temperature and air pollution on human mortality in Berlin and Lisbon, Environ Pollut, 2013. 183: p. 54-63., https://www.ncbi.nlm.nih.gov/pubmed/23941745

555. Ren, C., Williams, G. M., Morawska, L., Mengersen, K., Tong, S., Ozone modifies associations between temperature and cardiovascular mortality: analysis of the NMMAPS data, Occup Environ Med, 2008. 65(4): p. 255-60., https://www.ncbi.nlm.nih.gov/pubmed/17890300

556. Ren, C., Williams, G. M., Tong, S., Does particulate matter modify the association between temperature and cardiorespiratory diseases?, Environ Health Perspect, 2006. 114(11): p. 1690-6., https://www.ncbi.nlm.nih.gov/pubmed/17107854

557. Roberts, S., Interactions between particulate air pollution and temperature in air pollution mortality time series studies, Environ Res, 2004. 96(3): p. 328-37., https://www.ncbi.nlm.nih.gov/pubmed/15364601

558. Lucas, R. M., Yazar, S., Young, A. R., Norval, M., de Gruijl, F. R., Takizawa, Y., et.al. Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate, Photochem Photobiol Sci, 2019. 18(3): p. 641-680., https://www.ncbi.nlm.nih.gov/pubmed/30810559

559. National Radiological Protection Board, Ultraviolet radiation (UVR): health effects from exposure, 2002. 13:, https://www.gov.uk/government/publications/ultraviolet-radiation-uvr-health-effects-from-exposure

560. Rizwan, M., Reddick, C. L., Bundy, C., Unsworth, R., Richards, H. L., Rhodes, L. E., Photodermatoses: environmentally induced conditions with high psychological impact, Photochem Photobiol Sci, 2013. 12(1): p. 182-9., https://www.ncbi.nlm.nih.gov/pubmed/22961505

561. Stafford, R., Farrar, M. D., Kift, R., Durkin, M. T., Berry, J. L., Webb, A. R., et.al. The impact of photosensitivity disorders on aspects of lifestyle, Br J Dermatol, 2010. 163(4): p. 817-22., https://www.ncbi.nlm.nih.gov/pubmed/20545692

562. Rhodes, L. E., Bock, M., Janssens, A. S., Ling, T. C., Anastasopoulou, L., Antoniou, C., et.al. Polymorphic light eruption occurs in 18% of Europeans and does not show higher prevalence with increasing latitude: multicenter survey of 6,895 individuals residing from the Mediterranean to Scandinavia, J Invest Dermatol, 2010. 130(2): p. 626-8., https://www.ncbi.nlm.nih.gov/pubmed/19693026

563. Manney, G. L., Santee, M. L., Rex, M., Livesey, N. J., Pitts, M. C., Veefkind, P., et.al. Unprecedented Arctic ozone loss in 2011, Nature, 2011. 478(7370): p. 469-75., https://www.ncbi.nlm.nih.gov/pubmed/21964337

564. World Meteorological Organization (WMO), National Oceanic and Atmospheric, Administration (United States), United Nations Environment Programme, National Aeronautics and Space Administration (United States), European Commission, Scientific Assessment of Ozone Depletion: 2006: report of the Montreal Protocol Scientific Assessment Pane, 2007.

565. Mangold, A., Grooß, J. U., De Backer, H., Kirner, O., Ruhnke, R., Müller, R., A model study of the January 2006 low total ozone episode over Western Europe and comparison with ozone sonde data, Atmospheric Chemistry and Physics, 2009. 9(17): p. 6429-6451.

566. Siani, Anna Maria, Investigation on a low ozone episode at the end of November 2000 and its effect on ultraviolet radiation, Optical Engineering, 2002. 41(12): p. 3082-3089.

567. Werner, R., Valev, D., Atanassov, At., Kostadinov, I., Petkov, B., Giovanelli, G., et.al. Ozone mini-hole observation over the Balkan Peninsula in March 2005, Advances in Space Research, Volume 43, Numero 2, p.195-200, 2009.

568. Dobson, G.M.B., Harrison, D.N., Lawrence, J., Measurements of the amount of ozone in the Earth’s atmosphere and its relation to other geophysical conditions, 1929., https://doi.org/10.1098/rspa.1929.0034

569. Crutzen, Paul J., Arnold, Frank, Nitric acid cloud formation in the cold Antarctic stratosphere: a major cause for the springtime ‘ozone hole’, Nature, 1986. 324(6098): p. 651-655., https://doi.org/10.1038/324651a0

570. Molina, Mario J., Rowland, F. S., Stratospheric sink for chlorofluoromethanes: chlorine atom-catalysed destruction of ozone, Nature, 1974. 249(5460): p. 810-812., https://doi.org/10.1038/249810a0

571. World Meteorological Organization (WMO), Scientific Assessment of Ozone Depletion: 2010. World Meteorological Organization Report No. 52, 2010.

572. Hauchecorne, Alain, Quantification of the transport of chemical constituents from the polar vortex to midlatitudes in the lower stratosphere using the high-resolution advection model MIMOSA and effective diffusivity, Journal of Geophysical Research, 2002. 107(D20):

573. Arnone, E., Castelli, E., Papandrea, E., Carlotti, M., Dinelli, B. M., Extreme ozone depletion in the 2010–2011 Arctic winter stratosphere as observed by MIPAS/ENVISAT using a 2-D tomographic approach, Atmospheric Chemistry and Physics, 2012. 12(19): p. 9149-9165., https://www.atmos-chem-phys.net/12/9149/2012/

574. Koch, G., Wernli, H., Buss, S., Staehelin, J., Peter, T., Liniger, M. A., et.al. Quantification of the impact in mid-latitudes of chemical ozone depletion in the 1999/2000 Arctic polar vortex prior to the vortex breakup, Atmospheric Chemistry and Physics Discussions, 2004. 4(2): p. 1911-1940., https://www.atmos-chem-phys-discuss.net/4/1911/2004/

575. Rösevall, J.D., Murtagh, D.P., Urban, J., Feng, W., Eriksson, P., Brohede, S., A study of ozone depletion in the 2004/2005 Arctic winter based on data from Odin/SMR and Aura/MLS, Journal of Geophysical Research: Atmospheres, 2008. Volume 113, Issue D13:, https://doi.org/10.1029/2007JD009560

576. von Hobe, M., Bekki, S., Borrmann, S., Cairo, F., Amato, F.D., Di Donfrancesco, G., et.al. Reconciliation of essential process parameters for an enhancedpredictability of Arctic stratospheric ozone loss and its climateinteractions (RECONCILE): activities and results, Atmospheric Chemistry and Physics, 2013.

577. RECONCILE, Through dedicated laboratory and field measurements, RECONCILE has improved model representations of key processes dominating chemistry, microphysics and dynamics of Arctic stratospheric ozone loss, 2013., https://www.fp7-reconcile.eu

578. Stick, C., Krüger, K., Schade, N. H., Sandmann, H., Macke, A., Episode of unusual high solar ultraviolet radiation over central Europe due to dynamical reduced total ozone in May 2005, Atmospheric Chemistry and Physics, 2006. 6(7): p. 1771-1776.

579. Brönnimann, S., Hood, L.L., Low total ozone events over northwestern Europe in the 1950s and 1990s., Ozone. Proceedings of the XX Quadrennial Ozone Symposium, 1-8 June 2004, Kos, Greece (Ed. C. Zerefos), 1, 302-​303, 2004.

580. Reid, S. J., Tuck, A. F., Kiladis, G., On the changing abundance of ozone minima at northern midlatitudes, Journal of Geophysical Research: Atmospheres, 2000. 105(D10): p. 12169-12180.

581. Stenke, A., Grewe, V., Impact of ozone mini-holes on the heterogeneous destruction of stratospheric ozone, Chemosphere, 2003. 50(2): p. 177-90., https://www.ncbi.nlm.nih.gov/pubmed/12653290

582. Gesetz zur Stärkung der Gesundheitsförderung und der Prävention, 2015.

583. Bund/Lander Ad-hoc Arbeitsgruppe Gesundheitliche Anpassung an die Folgen des, Klimawandels, Handlungsempfehlungen fur die Erstellung von Hitzeaktionsplanen zum Schutz der menschlichen Gesundheit., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2017. 60(6): p. 662-672., https://www.ncbi.nlm.nih.gov/pubmed/28492969

584. Staiger, H., Laschewski, G., Gratz, A., The perceived temperature - a versatile index for the assessment of the human thermal environment. Part A: scientific basics, Int J Biometeorol, 2012. 56(1): p. 165-76., https://www.ncbi.nlm.nih.gov/pubmed/21336880

585. Stewart, A. E., Kimlin, M. G., The Dislike of Hot Thermal Conditions and Its Relationship with Sun (Ultraviolet Radiation) Exposure in the Southeastern United States, Int J Environ Res Public Health, 2018. 15(10):, https://www.ncbi.nlm.nih.gov/pubmed/30275387

586. Arana, P., Cabezudo, S., Peñalba, M., Influence of weather conditions on transit ridership: A statistical study using data from Smartcards, Transportation Research Part A: Policy and Practice, 2014. 59: p. 1-12., http://www.sciencedirect.com/science/article/pii/S0965856413002073

587. Banwell, C., Dixon, J., Bambrick, H., Edwards, F., Kjellstrom, T., Socio-cultural reflections on heat in Australia with implications for health and climate change adaptation, Glob Health Action, 2012. 5:, https://www.ncbi.nlm.nih.gov/pubmed/23078748

588. Belanger, M., Gray-Donald, K., O'Loughlin, J., Paradis, G., Hanley, J., Influence of weather conditions and season on physical activity in adolescents, Ann Epidemiol, 2009. 19(3): p. 180-6., https://www.ncbi.nlm.nih.gov/pubmed/19217000

589. Eisinga, R., Franses, P. H., Vergeer, M., Weather conditions and daily television use in the Netherlands, 1996-2005, Int J Biometeorol, 2011. 55(4): p. 555-64., https://www.ncbi.nlm.nih.gov/pubmed/20978912

590. Knuschke, P., Kurpiers, M., Koch, R., Kuhlisch, W., Wittke, K, Mittlere UV-Exposition der Bevölkerung. Schlussbericht des BMBF-Vorhabens 07UV-B54C/3., 2004.

591. Knuschke P., Unverricht I., Ott G., Janßen M., Personenbezogene Messung der UV-Exposition von Arbeitnehmern im Freien, Abschlussbericht Projekt F 1777, 2007.

592. Liu, Y., Kostakos, V., Li, H., Climatic effects on planning behavior, PLoS One, 2015. 10(5): p. e0126205., https://www.ncbi.nlm.nih.gov/pubmed/25993567

593. Spinney, J. E., Millward, H., Weather impacts on leisure activities in Halifax, Nova Scotia, Int J Biometeorol, 2011. 55(2): p. 133-45., https://www.ncbi.nlm.nih.gov/pubmed/20499254

594. Yang, Bin, Olofsson, Thomas, Nair, Gireesh, Kabanshi, Alan, Outdoor thermal comfort under subarctic climate of north Sweden – A pilot study in Umeå, Sustainable Cities and Society, 2017. 28: p. 387-397., http://www.sciencedirect.com/science/article/pii/S2210670716302554

595. Becker, Stefan, Potchter, Oded, Yaakov, Yaron, Calculated and observed human thermal sensation in an extremely hot and dry climate, Energy and Buildings, 2003. 35(8): p. 747-756.

596. Godar, D. E., UV doses worldwide, Photochem Photobiol, 2005. 81(4): p. 736-49., https://www.ncbi.nlm.nih.gov/pubmed/15819599

597. Godar, D. E., Urbach, F., Gasparro, F. P., van der Leun, J. C., UV doses of young adults, Photochem Photobiol, 2003. 77(4): p. 453-7., https://www.ncbi.nlm.nih.gov/pubmed/12733658

598. Gies, P., Roy, C., Toomey, S., Tomlinson, D., Ambient solar UVR, personal exposure and protection, J Epidemiol, 1999. 9(6 Suppl): p. S115-22., https://www.ncbi.nlm.nih.gov/pubmed/10709359

599. Kift, R., Berry, J. L., Vail, A., Durkin, M. T., Rhodes, L. E., Webb, A. R., Lifestyle factors including less cutaneous sun exposure contribute to starkly lower vitamin D levels in U.K. South Asians compared with the white population, Br J Dermatol, 2013. 169(6): p. 1272-8., https://www.ncbi.nlm.nih.gov/pubmed/23855783

600. Piacentini, R. D., Della Ceca, L. S., Ipina, A., Climate change and its relationship with non-melanoma skin cancers, Photochem Photobiol Sci, 2018. 17(12): p. 1913-1917., https://www.ncbi.nlm.nih.gov/pubmed/30334034

601. Gies, P., Mackay, C., Measurements of the solar UVR protection provided by shade structures in New Zealand primary schools, Photochem Photobiol, 2004. 80(2): p. 334-9., https://www.ncbi.nlm.nih.gov/pubmed/15264956

602. Kabisch, N., van den Bosch, M., Lafortezza, R., The health benefits of nature-based solutions to urbanization challenges for children and the elderly - A systematic review, Environ Res, 2017. 159: p. 362-373., https://www.ncbi.nlm.nih.gov/pubmed/28843167

603. Middel, A., Selover, N., Hagen, B., Chhetri, N., Impact of shade on outdoor thermal comfort-a seasonal field study in Tempe, Arizona, Int J Biometeorol, 2016. 60(12): p. 1849-1861., https://www.ncbi.nlm.nih.gov/pubmed/27192997

604. Antoniadis, D., Katsoulas, N., Papanastasiou, D., Christidou, V., Kittas, C., Evaluation of thermal perception in schoolyards under Mediterranean climate conditions, Int J Biometeorol, 2016. 60(3): p. 319-34., https://www.ncbi.nlm.nih.gov/pubmed/26190284

605. Buller, D. B., English, D. R., Buller, M. K., Simmons, J., Chamberlain, J. A., Wakefield, M., et.al. Shade Sails and Passive Recreation in Public Parks of Melbourne and Denver: A Randomized Intervention, Am J Public Health, 2017. 107(12): p. 1869-1875., https://www.ncbi.nlm.nih.gov/pubmed/29048958

606. Mahe, E., Correa, M. P., Godin-Beekmann, S., Haeffelin, M., Jegou, F., Saiag, P., et.al. Evaluation of tourists' UV exposure in Paris, J Eur Acad Dermatol Venereol, 2013. 27(3): p. e294-304., https://www.ncbi.nlm.nih.gov/pubmed/22775064

607. Sliney, D. H., Physical factors in cataractogenesis: ambient ultraviolet radiation and temperature, Invest Ophthalmol Vis Sci, 1986. 27(5): p. 781-90., https://www.ncbi.nlm.nih.gov/pubmed/3700027

608. Victoria, Cancer Council, Shade Guidelines, 2015.

609. Parisi, A. V., Turnbull, D. J., Shade provision for UV minimization: a review, Photochem Photobiol, 2014. 90(3): p. 479-90., https://www.ncbi.nlm.nih.gov/pubmed/24417678

610. Streiling, S., Matzarakis, A., Streiling, S., A. Matzarakis, (2003). Influence of singular trees and small clusters of trees on the bioclimate of a city – a case study. Journal of Arboriculture 29, 309-316, Journal of Arboriculture, 2003. 20: p. 309-316.

611. Gies, P., Elix, R., Lawry, D., Gardner, J., Hancock, T., Cockerell, S., et.al. Assessment of the UVR protection provided by different tree species, Photochem Photobiol, 2007. 83(6): p. 1465-70., https://www.ncbi.nlm.nih.gov/pubmed/18028222

612. Buller, D. B., Dobbinson, S., English, D. R., Wakefield, M., Buller, M. K., Rationale, design, and baseline data of a cross-national randomized trial on the effect of built shade in public parks for sun protection, Contemp Clin Trials, 2017. 55: p. 47-55., https://www.ncbi.nlm.nih.gov/pubmed/28185996

613. Knieling, J., Fröhlich, J., Greiving, S., Kannen, A., Morgenstern, N., Moss, T., et.al. Planerisch-organisatorischeAnpassungspotenziale an den Klimawandel, 2011.

614. Deutsche Gesetzliche Unfallversicherung (DGUV) e.V., Prävention - Sonnenschutz, https://www.dguv.de/de/praevention/themen-a-z/sonne/index.jsp

615. Deutsche Gesetzliche Unfallversicherung (DGUV) e.V., DGUV-Arbeitshilfe „Hautkrebs durch UV-Strahlung", 2013., https://www.dguv.de/medien/inhalt/versicherung/berufskrankheiten/hauterkrankungen/hautkrebs/dguv_arbeitshilfe_hautkrebs.pdf

616. Bundesrepublik Deutschland, Beschluss des Bundesrates: Zweite Verordnung zur Änderung der Verordnung zur arbeitsmedizinischen Vorsorge, 2019. Bundesdrucksache 237/19, 1-21:, https://www.bmas.de/SharedDocs/Downloads/DE/PDF-Gesetze/Regierungsentwuerfe/reg-zweite-verordnung-aenderung-verordnung-zur-arbeitsmedizinischen-vorsorge.pdf;jsessionid=5343C9B39F76571E42C10149A20324A9?__blob=publicationFile&v=3

617. Diffey, B., Personal ultraviolet radiation dosimetry with polysulphone film badges, Photodermatol, 1984. 1(3): p. 151-7., https://www.ncbi.nlm.nih.gov/pubmed/6527960

618. Holman, C.D.J., Gibson, I.M., Stephenson, M., Armstrong, B.K., Ultraviolet irradiation of human body sites in relation to occupation and outdoor activity: field studies using personal UVR dosimeters, 1983.

619. Knuschke, P., Krins, A., UV-Personendosimetrie Teil B: Mit Verwendung des Polysulfonfilms als UV-Sensor; Schlussbericht BMBF-Vorhaben 07UVB54B, 2000.

620. Thieden, E., Agren, M. S., Wulf, H. C., The wrist is a reliable body site for personal dosimetry of ultraviolet radiation, Photodermatol Photoimmunol Photomed, 2000. 16(2): p. 57-61., https://www.ncbi.nlm.nih.gov/pubmed/10823313

621. Thieden, E., Agren, M. S., Wulf, H. C., Solar UVR exposures of indoor workers in a Working and a Holiday Period assessed by personal dosimeters and sun exposure diaries, Photodermatol Photoimmunol Photomed, 2001. 17(6): p. 249-55., https://www.ncbi.nlm.nih.gov/pubmed/11722749

622. Wittlich, M., Westerhausen, S., Kleinespel, P., Rifer, G., Stoppelmann, W., An approximation of occupational lifetime UVR exposure: algorithm for retrospective assessment and current measurements, J Eur Acad Dermatol Venereol, 2016. 30 Suppl 3: p. 27-33., https://www.ncbi.nlm.nih.gov/pubmed/26995020

623. Serrano, M. A., Canada, J., Moreno, J. C., Solar Radiation, Group, Erythemal ultraviolet exposure in two groups of outdoor workers in Valencia, Spain, Photochem Photobiol, 2009. 85(6): p. 1468-73., https://www.ncbi.nlm.nih.gov/pubmed/19709385

624. Serrano, M. A., Canada, J., Moreno, J. C., Gurrea, G., Members of the Valencia Solar Radiation Research, Group, Occupational UV exposure of environmental agents in Valencia, Spain, Photochem Photobiol, 2014. 90(4): p. 911-8., https://www.ncbi.nlm.nih.gov/pubmed/24494834

625. Kovacic, Personal ultraviolet radiation dosimetry and its relationship with environmental data: a longitudinal pilot study in Croatian construction workers, in Review.

626. Wittlich, M., John, S. M., Tiplica, G. S., Salavastru, C. M., Butacu, A. I., Modenese, A., et.al. Personal solar ultraviolet radiation dosimetry in an occupational setting across Europe, J Eur Acad Dermatol Venereol, 2020. n/a(n/a):, https://www.ncbi.nlm.nih.gov/pubmed/32080895

627. Knuschke, P., Unverricht, I., Ott, G., Janßen, M., Personenbezogene Messungder UV-Exposition vonArbeitnehmern im Freien, 2007. ForschungProjekt F 1777:

628. Bundesamt für Justiz, Arbeitsschutzgesetz - ArbSchG, zuletzt geändert am 31.08.2015., https://www.gesetze-im-internet.de/arbschg/__12.html

629. Deutsche Gesetzliche Unfallversicherung e.V. (DGUV), DGUV Information 203-085: Arbeiten unter der Sonne, 2016., https://publikationen.dguv.de/dguv/udt_dguv_main.aspx?FDOCUID=26486

630. Ruppert L., Ofenloch R., Surber C., Diepgen T.L., Wirksamkeit beruflicher Hautkrebspräventionsmaßnahmen - Eine randomisierte Clusterumfrage unter Berufsschülern beschäftigt an Outdoor-Arbeitsplätzen in Deutschland, Dermatologie in Beruf und Umwelt, Jahrgang 66, Nr. 4/2018, 2018. p. 159-174.

631. Andersen, Peter A., Buller, David B., Voeks, Jenifer H., Walkosz, Barbara J., Scott, Michael D., Cutter, Gary R., et.al. Testing the long-term effects of the Go Sun Smart worksite health communication campaign: A group-randomized experimental study, Journal of Communication, 2008. 58(3): p. 447-471., http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc6&AN=2008-12578-003, http://sfx.gbv.de/sfx_subhh?sid=OVID:psycdb&id=pmid:&id=doi:10.1111%2Fj.1460-2466.2008.00394.x&issn=0021-9916&isbn=&volume=58&issue=3&spage=447&pages=447-471&date=2008&title=Journal+of+Communication&atitle=Testing+the+long-term+effects+of+the+Go+Sun+Smart+worksite+health+communication+campaign%3A+A+group-randomized+experimental+study.&aulast=Andersen, http://dx.doi.org/10.1111/j.1460-2466.2008.00394.x

632. Kearney, G. D., Xu, X., Balanay, J. A., Becker, A. J., Sun safety among farmers and farmworkers: a review, J Agromedicine, 2014. 19(1): p. 53-65., https://www.ncbi.nlm.nih.gov/pubmed/24417532

633. Mayer, J. A., Slymen, D. J., Clapp, E. J., Pichon, L. C., Eckhardt, L., Eichenfield, L. F., et.al. Promoting sun safety among US Postal Service letter carriers: impact of a 2-year intervention, Am J Public Health, 2007. 97(3): p. 559-65., https://www.ncbi.nlm.nih.gov/pubmed/17267715

634. Stock, M. L., Gerrard, M., Gibbons, F. X., Dykstra, J. L., Weng, C. Y., Mahler, H. I., et.al. Sun protection intervention for highway workers: long-term efficacy of UV photography and skin cancer information on men's protective cognitions and behavior, Ann Behav Med, 2009. 38(3): p. 225-36., https://www.ncbi.nlm.nih.gov/pubmed/20049658

635. Houdmont, J., Madgwick, P., Randall, R., Sun safety in construction: a U.K. intervention study, Occup Med (Lond), 2016. 66(1): p. 20-6., https://www.ncbi.nlm.nih.gov/pubmed/26409050

636. Thieden, E., Collins, S. M., Philipsen, P. A., Murphy, G. M., Wulf, H. C., Ultraviolet exposure patterns of Irish and Danish gardeners during work and leisure, Br J Dermatol, 2005. 153(4): p. 795-801., https://www.ncbi.nlm.nih.gov/pubmed/16181463

637. Bundesministerium für Arbeit und Soziales (BMAS), Zweite Verordnung zur Änderung der Verordnung zur arbeitsmedizinischen Vorsorge, 2019. Bundesdrucksache 237/19, 1-21:

638. Deutsche Gesetzliche Unfallversicherung (DGUV) e.V., Honorare in der Berufsdermatologie – Ein Leitfaden für die Abrechnung von A bis Z, 2019. Stand 10/2019:, https://publikationen.dguv.de/versicherungleistungen/berufskrankheiten/3207/honorare-in-der-berufsdermatologie-ein-leitfaden-fuer-die-abrechnung-von-a-bis-z

639. Beaglehole, R., Bonita, R., Kjellström, T., Einführung in die EpidemiologieHogrefe, Hans Huber, 1997.

640. Giersiepen, K., Hense, H., Klug, S., Antes, G., Zeeb, H., Entwicklung, Durchführung und Evaluation von Programmen zur Krebsfrüherkennung. Ein Positionspapier, Zeitschrift für ärztliche Fortbildung und Qualität im Gesundheitswesen, 2007. 101(1): p. 43-49.

641. Brantsch, K. D., Meisner, C., Schonfisch, B., Trilling, B., Wehner-Caroli, J., Rocken, M., et.al. Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study, Lancet Oncol, 2008. 9(8): p. 713-20., https://www.ncbi.nlm.nih.gov/pubmed/18617440

642. Wilson, J.M.G., Jungner, G., Principles and Practice of Screening for DiseaseWorld Health Organization, 1968.

643. Spix, C., Blettner, M., Screening: part 19 of a series on evaluation of scientific publications, Dtsch Arztebl Int, 2012. 109(21): p. 385-90., https://www.ncbi.nlm.nih.gov/pubmed/22690254

644. Schwartz. F. W., Holstein, H., Brecht, J. G., Ergebnisse der gesetzlichen Frükerkennung unter Effektivitätsgesichtspunkten, in Probleme einer systematischen Früherkennung, van Eimeren, W. and Neiß, A., Editors. 1979, Springer: Berlin, Heidelberg, New York. p. 62-63.

645. Morrison, A.S., Screening in chronic diseaseUniversity Press, 1992.

646. Andermann, A., Blancquaert, I., Beauchamp, S., Dery, V., Revisiting Wilson and Jungner in the genomic age: a review of screening criteria over the past 40 years, Bull World Health Organ, 2008. 86(4): p. 317-9., https://www.ncbi.nlm.nih.gov/pubmed/18438522

647. Gemeinsamer Bundesausschuss, Richtlinie des Gemeinsamen Bundesausschusses über die Früherkennung von Krebserkrankungen (Krebsfrüherkennungs-Richtlinie / KFE-RL), Bundesanzeiger, 2009. Nr. 148a:

648. Gordis, L., EpidemiologyElsevier / Saunders, 2009.

649. Gordis, L., EpidemiologyElsevier / Saunders, 2009.

650. Schmitt, J., Seidler, A., Heinisch, G., Sebastian, G., Effectiveness of skin cancer screening for individuals age 14 to 34 years, J Dtsch Dermatol Ges, 2011. 9(8): p. 608-16., https://www.ncbi.nlm.nih.gov/pubmed/21501381

651. Engelberg, D., Gallagher, R. P., Rivers, J. K., Follow-up and evaluation of skin cancer screening in British Columbia, J Am Acad Dermatol, 1999. 41(1): p. 37-42., https://www.ncbi.nlm.nih.gov/pubmed/10411408

652. Guther, S., Ramrath, K., Dyall-Smith, D., Landthaler, M., Stolz, W., Development of a targeted risk-group model for skin cancer screening based on more than 100,000 total skin examinations, J Eur Acad Dermatol Venereol, 2012. 26(1): p. 86-94., https://www.ncbi.nlm.nih.gov/pubmed/21371132

653. U.S. Preventive Services Task Force, Screening for Skin Cancer- Recommendations and Rationale, Am J Prev Med, 2001. 20:

654. Wolff, T., Tai, E., Miller, T., Screening for skin cancer: an update of the evidence for the U.S. Preventive Services Task Force, Ann Intern Med, 2009. 150(3): p. 194-8., https://www.ncbi.nlm.nih.gov/pubmed/19189909

655. Australian Cancer Network Melanoma Guidelines Revision Working Party, Clinical Practice Guidelines for the Management of Melanoma in Australia and New ZealandThe Cancer Council Australia and Australian Cancer Network, Sydney and New Zealand Guidelines Group, 2008.

656. Osborne, J. E., Chave, T. A., Hutchinson, P. E., Comparison of diagnostic accuracy for cutaneous malignant melanoma between general dermatology, plastic surgery and pigmented lesion clinics, Br J Dermatol, 2003. 148(2): p. 252-8., https://www.ncbi.nlm.nih.gov/pubmed/12588376

657. Pacifico, M. D., Pearl, R. A., Grover, R., The UK Government two-week rule and its impact on melanoma prognosis: an evidence-based study, Ann R Coll Surg Engl, 2007. 89(6): p. 609-15., https://www.ncbi.nlm.nih.gov/pubmed/18201477

658. U.S. Preventive Services Task Force, Screening for Skin Cancer- Recommendations and Rationale, Am J Prev Med, 2001. 20:, https://www.ncbi.nlm.nih.gov/pubmed/11306231

659. Scottish Intercollegiate Guidelines Network, SIGN 72: Cutaneous Melanoma - A national clinical guidelineScottish Intercollegiate Guidelines Network, 2003., www.sign.ac.uk

660. Titus, L. J., Clough-Gorr, K., Mackenzie, T. A., Perry, A., Spencer, S. K., Weiss, J., et.al. Recent skin self-examination and doctor visits in relation to melanoma risk and tumour depth, Br J Dermatol, 2013. 168(3): p. 571-6., https://www.ncbi.nlm.nih.gov/pubmed/22897437

661. Paddock, L. E., Lu, S. E., Bandera, E. V., Rhoads, G. G., Fine, J., Paine, S., et.al. Skin self-examination and long-term melanoma survival, Melanoma Res, 2016. 26(4): p. 401-8., https://www.ncbi.nlm.nih.gov/pubmed/26990272

662. Chiu, V., Won, E., Malik, M., Weinstock, M. A., The use of mole-mapping diagrams to increase skin self-examination accuracy, J Am Acad Dermatol, 2006. 55(2): p. 245-50., https://www.ncbi.nlm.nih.gov/pubmed/16844506

663. Hanrahan, P. F., D'Este, C. A., Menzies, S. W., Plummer, T., Hersey, P., A randomised trial of skin photography as an aid to screening skin lesions in older males, J Med Screen, 2002. 9(3): p. 128-32., https://www.ncbi.nlm.nih.gov/pubmed/12370325

664. Oliveria, S. A., Chau, D., Christos, P. J., Charles, C. A., Mushlin, A. I., Halpern, A. C., Diagnostic accuracy of patients in performing skin self-examination and the impact of photography, Arch Dermatol, 2004. 140(1): p. 57-62., https://www.ncbi.nlm.nih.gov/pubmed/14732661

665. Muhn, C. Y., From, L., Glied, M., Detection of artificial changes in mole size by skin self-examination, J Am Acad Dermatol, 2000. 42(5 Pt 1): p. 754-9., https://www.ncbi.nlm.nih.gov/pubmed/10775850

666. Moffatt, C. R., Green, A. C., Whiteman, D. C., Diagnostic accuracy in skin cancer clinics: the Australian experience, Int J Dermatol, 2006. 45(6): p. 656-60., https://www.ncbi.nlm.nih.gov/pubmed/16796621

667. Katris, P., Donovan, R. J., Gray, B. N., Nurses screening for skin cancer: an observation study, Aust N Z J Public Health, 1998. 22(3 Suppl): p. 381-3., https://www.ncbi.nlm.nih.gov/pubmed/9629826

668. Mogensen, M., Jemec, G. B., Diagnosis of nonmelanoma skin cancer/keratinocyte carcinoma: a review of diagnostic accuracy of nonmelanoma skin cancer diagnostic tests and technologies, Dermatol Surg, 2007. 33(10): p. 1158-74., https://www.ncbi.nlm.nih.gov/pubmed/17903149

669. Kai, Y., Ishikawa, K., Goto, M., Sakai, T., Ito, A., Shono, T., et.al. Results of second-stage screening for skin cancers in Oita Prefecture, Japan, J Dermatol, 2015. 42(12): p. 1160-4., https://www.ncbi.nlm.nih.gov/pubmed/26177589

670. Burton, R. C., Howe, C., Adamson, L., Reid, A. L., Hersey, P., Watson, A., et.al. General practitioner screening for melanoma: sensitivity, specificity, and effect of training, J Med Screen, 1998. 5(3): p. 156-61., https://www.ncbi.nlm.nih.gov/pubmed/9795877

671. Bono, A., Bartoli, C., Cascinelli, N., Lualdi, M., Maurichi, A., Moglia, D., et.al. Melanoma detection. A prospective study comparing diagnosis with the naked eye, dermatoscopy and telespectrophotometry, Dermatology, 2002. 205(4): p. 362-6., https://www.ncbi.nlm.nih.gov/pubmed/12444332

672. Chen, S. C., Bravata, D. M., Weil, E., Olkin, I., A comparison of dermatologists' and primary care physicians' accuracy in diagnosing melanoma: a systematic review, Arch Dermatol, 2001. 137(12): p. 1627-34., https://www.ncbi.nlm.nih.gov/pubmed/11735713

673. Ferris, L. K., Saul, M. I., Lin, Y., Ding, F., Weinstock, M. A., Geller, A. C., et.al. A Large Skin Cancer Screening Quality Initiative: Description and First-Year Outcomes, JAMA Oncol, 2017. 3(8): p. 1112-1115., https://www.ncbi.nlm.nih.gov/pubmed/28241191

674. Cristofolini, M., Boi, S., Cattoni, D., Sicher, M. C., Decarli, A., Micciolo, R., A 10-Year Follow-Up Study of Subjects Recruited in a Health Campaign for the Early Diagnosis of Cutaneous Melanoma: Suggestions for the Screening Timetable, Dermatology, 2015. 231(4): p. 345-52., https://www.ncbi.nlm.nih.gov/pubmed/26278413

675. Aitken, J. F., Elwood, M., Baade, P. D., Youl, P., English, D., Clinical whole-body skin examination reduces the incidence of thick melanomas, Int J Cancer, 2010. 126(2): p. 450-8., https://www.ncbi.nlm.nih.gov/pubmed/19609948

676. Melia, J., Moss, S., Coleman, D., Frost, T., Graham-Brown, R., Hunter, J. A., et.al. The relation between mortality from malignant melanoma and early detection in the Cancer Research Campaign Mole Watcher Study, Br J Cancer, 2001. 85(6): p. 803-7., https://www.ncbi.nlm.nih.gov/pubmed/11556828

677. Helfand, M., Mahon, S. M., Eden, K. B., Frame, P. S., Orleans, C. T., Screening for skin cancer, Am J Prev Med, 2001. 20(3 Suppl): p. 47-58., https://www.ncbi.nlm.nih.gov/pubmed/11306232

678. Aitken, J. F., Elwood, J. M., Lowe, J. B., Firman, D. W., Balanda, K. P., Ring, I. T., A randomised trial of population screening for melanoma, J Med Screen, 2002. 9(1): p. 33-7., https://www.ncbi.nlm.nih.gov/pubmed/11943795

679. Aitken, J. F., Youl, P. H., Janda, M., Lowe, J. B., Ring, I. T., Elwood, M., Increase in skin cancer screening during a community-based randomized intervention trial, Int J Cancer, 2006. 118(4): p. 1010-6., https://www.ncbi.nlm.nih.gov/pubmed/16152577

680. Janda, M., Lowe, J. B., Elwood, M., Ring, I. T., Youl, P. H., Aitken, J. F., Do centralised skin screening clinics increase participation in melanoma screening (Australia)?, Cancer Causes Control, 2006. 17(2): p. 161-8., https://www.ncbi.nlm.nih.gov/pubmed/16425094

681. Watts, C. G., Dieng, M., Morton, R. L., Mann, G. J., Menzies, S. W., Cust, A. E., Clinical practice guidelines for identification, screening and follow-up of individuals at high risk of primary cutaneous melanoma: a systematic review, Br J Dermatol, 2015. 172(1): p. 33-47., https://www.ncbi.nlm.nih.gov/pubmed/25204572

682. Oliveria, S. A., Dusza, S. W., Phelan, D. L., Ostroff, J. S., Berwick, M., Halpern, A. C., Patient adherence to skin self-examination. effect of nurse intervention with photographs, Am J Prev Med, 2004. 26(2): p. 152-5., https://www.ncbi.nlm.nih.gov/pubmed/14751328

683. Fortes, C., Commentary: Reproductibility of skin characteristic measurments and reported sun exposure history, International Journal of Epidemiology, 2002. 31(2): p. 446-8.

684. Carli, P., Chiarugi, A., De Giorgi, V., Examination of lesions (including dermoscopy) without contact with the patient is associated with improper management in about 30% of equivocal melanomas, Dermatol Surg, 2005. 31(2): p. 169-72., https://www.ncbi.nlm.nih.gov/pubmed/15762209

685. Kaiser, M., Schiller, J., Schreckenberger, C., The effectiveness of a population-based skin cancer screening program: evidence from Germany, Eur J Health Econ, 2018. 19(3): p. 355-367., https://www.ncbi.nlm.nih.gov/pubmed/28353004

686. Eisemann, N., Waldmann, A., Geller, A. C., Weinstock, M. A., Volkmer, B., Greinert, R., et.al. Non-melanoma skin cancer incidence and impact of skin cancer screening on incidence, J Invest Dermatol, 2014. 134(1): p. 43-50., https://www.ncbi.nlm.nih.gov/pubmed/23877569

687. Eisemann, N., Waldmann, A., Katalinic, A., [Incidence of melanoma and changes in stage-specific incidence after implementation of skin cancer screening in Schleswig-Holstein], Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2014. 57(1): p. 77-83., https://www.ncbi.nlm.nih.gov/pubmed/24357176

688. Stang, A., Jöckel, K. H., Heidinger, O., Skin cancer rates in North Rhine-Westphalia, Germany before and after the introduction of the nationwide skin cancer screening program (2000–2015), European Journal of Epidemiology, 2018. 33: p. 303-312.

689. Trautmann, F., Meier, F., Seidler, A., Schmitt, J., Effects of the German skin cancer screening programme on melanoma incidence and indicators of disease severity, Br J Dermatol, 2016. 175(5): p. 912-919., https://www.ncbi.nlm.nih.gov/pubmed/27203791

690. Hubner, J., Waldmann, A., Geller, A. C., Weinstock, M. A., Eisemann, N., Noftz, M., et.al. Interval cancers after skin cancer screening: incidence, tumour characteristics and risk factors for cutaneous melanoma, Br J Cancer, 2017. 116(2): p. 253-259., https://www.ncbi.nlm.nih.gov/pubmed/27898656

691. Boniol, M., Autier, P., Gandini, S., Melanoma mortality following skin cancer screening in Germany, BMJ Open, 2015. 5(9): p. e008158., https://www.ncbi.nlm.nih.gov/pubmed/26373399

692. Stang, A., Jockel, K. H., Does skin cancer screening save lives? A detailed analysis of mortality time trends in Schleswig-Holstein and Germany, Cancer, 2016. 122(3): p. 432-7., https://www.ncbi.nlm.nih.gov/pubmed/26480048

693. Schubert, A., [Malignant melanoma of the skin: does screening for cancer influence the incidence and mortality?], Gesundheitswesen, 2012. 74(3): p. 154-9., https://www.ncbi.nlm.nih.gov/pubmed/21305450

694. Lüken, F., Batz, D., Kutschmann, M., Evaluation der Screeninguntersuchungen auf Hautkrebs gemäß Krebsfrüherkennungs-Richtlinie des Gemeinsamen Bundesauschusses. Abschlussbericht der Jahre 2011-2013.BQS Institut für Qualität & Patientensicherheit, 2016.

695. Arbeitsgemeinschaft Dermatologische Prävention, Abschlussbericht zur Phase III („Pilotphase“) des Projektes Weiterentwicklung der Hautkrebsfrüherkennung im Rahmen der gesetzlichen Krebsfrüherkennungsuntersuchung (KFU) als Vorbereitung für die flächendeckende EinführungGemeinsamer Bundesausschuss (German Joint Federal Committee), 2005., http://www.g-ba.de/downloads/40-268-1748/2007-11-15_HKS-Abschlussbericht_2004.pdf

696. Kommission Hautkrebs-Screening Deutschland, Fortbildungsprogramm Hautkrebs-ScreeningDeutscher Ärzte-Verlag, 2008.

697. Gemeinsamer Bundesausschuss, Richtlinie des Gemeinsamen Bundesausschusses über die Früherkennung von Krebserkrankungen (Krebsfrüherkennungs-Richtlinie / KFE-RL), Bundesanzeiger, 2018. Nr. 148a:, https://www.g-ba.de/downloads/39-261-3203/2018-01-18_KFE-RL_Anpassung-Doku-Hautkrebsscreening_BAnz.pdf?

698. Anders, M. P., Fengler, S., Volkmer, B., Greinert, R., Breitbart, E. W., Nationwide skin cancer screening in Germany: Evaluation of the training program, Int J Dermatol, 2017. 56(10): p. 1046-1051., https://www.ncbi.nlm.nih.gov/pubmed/28832980

699. Choudhury, K., Unveröffentlichter Abschlussbericht SCSES, 2019.

700. Markova, A., Weinstock, M. A., Risica, P., Kirtania, U., Shaikh, W., Ombao, H., et.al. Effect of a web-based curriculum on primary care practice: basic skin cancer triage trial, Fam Med, 2013. 45(8): p. 558-68., https://www.ncbi.nlm.nih.gov/pubmed/24129868

701. Bedlow, A. J., Cliff, S., Melia, J., Moss, S. M., Seyan, R., Harland, C. C., Impact of skin cancer education on general practitioners' diagnostic skills, Clin Exp Dermatol, 2000. 25(2): p. 115-8., https://www.ncbi.nlm.nih.gov/pubmed/10733633

702. Benvenuto-Andrade, C., Dusza, S. W., Hay, J. L., Agero, A. L., Halpern, A. C., Kopf, A. W., et.al. Level of confidence in diagnosis: clinical examination versus dermoscopy examination, Dermatol Surg, 2006. 32(5): p. 738-44., https://www.ncbi.nlm.nih.gov/pubmed/16706773

703. Cliff, S., Bedlow, A. J., Melia, J., Moss, S., Harland, C. C., Impact of skin cancer education on medical students' diagnostic skills, Clin Exp Dermatol, 2003. 28(2): p. 214-7., https://www.ncbi.nlm.nih.gov/pubmed/12653717

704. de Gannes, G. C., Ip, J. L., Martinka, M., Crawford, R. I., Rivers, J. K., Early detection of skin cancer by family physicians: a pilot project, J Cutan Med Surg, 2004. 8(2): p. 103-9., https://www.ncbi.nlm.nih.gov/pubmed/15037942

705. Dolev, J. C., O'Sullivan, P., Berger, T., The eDerm online curriculum: a randomized study of effective skin cancer teaching to medical students, J Am Acad Dermatol, 2011. 65(6): p. e165-71., https://www.ncbi.nlm.nih.gov/pubmed/21112668

706. Gerbert, B., Bronstone, A., Maurer, T., Berger, T., McPhee, S. J., Caspers, N., The effectiveness of an Internet-based tutorial in improving primary care physicians' skin cancer triage skills, J Cancer Educ, 2002. 17(1): p. 7-11., https://www.ncbi.nlm.nih.gov/pubmed/12000111

707. Girgis, A., Sanson-Fisher, R. W., Howe, C., Raffan, B., A skin cancer training programme: evaluation of a postgraduate training for family doctors, Med Educ, 1995. 29(5): p. 364-71., https://www.ncbi.nlm.nih.gov/pubmed/8699975

708. Goulart, J. M., Quigley, E. A., Dusza, S., Jewell, S. T., Alexander, G., Asgari, M. M., et.al. Skin cancer education for primary care physicians: a systematic review of published evaluated interventions, J Gen Intern Med, 2011. 26(9): p. 1027-35., https://www.ncbi.nlm.nih.gov/pubmed/21472502

709. McCormick, L. K., Masse, L. C., Cummings, S. S., Burke, C., Evaluation of a skin cancer prevention module for nurses: change in knowledge, self-efficacy, and attitudes, Am J Health Promot, 1999. 13(5): p. 282-9., https://www.ncbi.nlm.nih.gov/pubmed/10538643

710. Mikkilineni, R., Weinstock, M. A., Goldstein, M. G., Dube, C. E., Rossi, J. S., The impact of the basic skin cancer triage curriculum on provider's skin cancer control practices, J Gen Intern Med, 2001. 16(5): p. 302-7., https://www.ncbi.nlm.nih.gov/pubmed/11359548

711. Gerbert, B., Bronstone, A., Wolff, M., Maurer, T., Berger, T., Pantilat, S., et.al. Improving primary care residents' proficiency in the diagnosis of skin cancer, J Gen Intern Med, 1998. 13(2): p. 91-7., https://www.ncbi.nlm.nih.gov/pubmed/9502368

712. Chen, J. G., Fleischer, A. B., Jr., Smith, E. D., Kancler, C., Goldman, N. D., Williford, P. M., et.al. Cost of nonmelanoma skin cancer treatment in the United States, Dermatol Surg, 2001. 27(12): p. 1035-8., https://www.ncbi.nlm.nih.gov/pubmed/11849266

713. Perry, N., Broeders, M., Wolf, C. de, Toernberg, S., Holland, R., Karsa, L. von, et.al. European guidelines for quality assurance in breast cancer screening and diagnosis (4th edition)Office for Official Publications of the European Communities, 2006. Fourth Edition:, https://www.ncbi.nlm.nih.gov/pubmed/18024988

714. Kassenärztliche Bundesvereinigung, IT in der Arztpraxis: Anforderungskatalog Hautkrebs-Screening (eHKS), 2012.

715. Hentschel, Stefan, Katalinic, Alexander, Das Manual der epidemiologischen KrebsregistrierungZuckschwerdt, 2011. 1. Auflage:

716. Gemeinsamer Bundesausschuss, Richtlinie des Gemeinsamen Bundesausschusses über die Früherkennung von Krebserkrankungen (Krebsfrüherkennungs-Richtlinie / KFE-RL), Bundesanzeiger, 2009. Nr. 148a:

717. Schmidtmann, Irene, Hammer, Gaël, Sariyar, Murat, Gerhold-Ay, Aslihan, Evaluation des Krebsregisters NRW: Schwerpunkt Record Linkage (Abschlussbericht 11.06.2009), 2009., www.krebsregister.nrw.de/fileadmin/user_upload/dokumente/Evaluation/EKR_NRW_Evaluation_Abschlussbericht_2009-06-11.pdf

718. Augustin, Matthias, Stadler, Rudolf, Reusch, Michael, Schäfer, Ines, Kornek, Thomas, Luger, Thomas, Gesetzliches Hautkrebsscreening in Deutschland: Wahrnehmung in der Oeffentlichkeit. Skin cancer screening in Germany - perception by the public, Journal der Deutschen Dermatologischen Gesellschaft, 2012. 10(ger):, http://www.zbmed.de/ccmedimages/2012/ZBMED-20121115153-3.pdf

719. Eissing, L., Schafer, I., Stromer, K., Kaufmann, R., Enk, A., Reusch, M., et.al. [Perception of statutory skin cancer screening in the general population : Current findings on participation, knowledge and evaluation], Hautarzt, 2017. 68(5): p. 371-376., https://www.ncbi.nlm.nih.gov/pubmed/28246676

720. Sullivan, H. W., Rutten, L. J., Hesse, B. W., Moser, R. P., Rothman, A. J., McCaul, K. D., Lay representations of cancer prevention and early detection: associations with prevention behaviors, Prev Chronic Dis, 2010. 7(1): p. A14., https://www.ncbi.nlm.nih.gov/pubmed/20040229

721. Davis, J. L., Buchanan, K. L., Katz, R. V., Green, B. L., Gender differences in cancer screening beliefs, behaviors, and willingness to participate: implications for health promotion, Am J Mens Health, 2012. 6(3): p. 211-7., https://www.ncbi.nlm.nih.gov/pubmed/22071507

722. Janda, M., Youl, P. H., Lowe, J. B., Baade, P. D., Elwood, M., Ring, I. T., et.al. What motivates men age > or =50 years to participate in a screening program for melanoma?, Cancer, 2006. 107(4): p. 815-23., https://www.ncbi.nlm.nih.gov/pubmed/16832794

723. Starker, A., Sass, A. C., [Participation in cancer screening in Germany: results of the German Health Interview and Examination Survey for Adults (DEGS1)], Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2013. 56(5-6): p. 858-67., https://www.ncbi.nlm.nih.gov/pubmed/23703507

724. Bundesministerium für Gesundheit, „Inanspruchnahme Krebsfrüherkennung“, Handlungsfeld 1 „Weiterentwicklung der Krebsfrüherkennung“ des Nationalen Krebsplans, 2017., http://www.bmg.bund.de/fileadmin/dateien/Downloads/N/Nationaler_Krebsplan/Ziel_1_Inanspruchnahme_der_Krebsfrueherkennung.pdf

725. Rimer, B. K., Briss, P. A., Zeller, P. K., Chan, E. C., Woolf, S. H., Informed decision making: what is its role in cancer screening?, Cancer, 2004. 101(5 Suppl): p. 1214-28., https://www.ncbi.nlm.nih.gov/pubmed/15316908

726. Bundesministerium für Gesundheit, „Inanspruchnahme Krebsfrüherkennung“, Handlungsfeld 1 „Weiterentwicklung der Krebsfrüherkennung“ des Nationalen Krebsplans, 2010., http://www.bmg.bund.de/fileadmin/dateien/Downloads/N/Nationaler_Krebsplan/Ziel_1_Inanspruchnahme_der_Krebsfrueherkennung.pdf

727. Luhnen, J., Albrecht, M., Hanssen, K., Hildebrandt, J., Steckelberg, A., [Guideline for the Development of Evidence-based Patient Information: insights into the methods and implementation of evidence-based health information], Z Evid Fortbild Qual Gesundhwes, 2015. 109(2): p. 159-65., https://www.ncbi.nlm.nih.gov/pubmed/26028454

728. Schwartz, L. M., Woloshin, S., Black, W. C., Welch, H. G., The role of numeracy in understanding the benefit of screening mammography, Ann Intern Med, 1997. 127(11): p. 966-72., https://www.ncbi.nlm.nih.gov/pubmed/9412301

729. Akl, E. A., Oxman, A. D., Herrin, J., Vist, G. E., Terrenato, I., Sperati, F., et.al. Using alternative statistical formats for presenting risks and risk reductions, Cochrane Database Syst Rev, 2011. p. CD006776., https://www.ncbi.nlm.nih.gov/pubmed/21412897

730. Reifegerste, D., Gesundheitskommunikation in der Prävention und Gesundheitsförderung für schwer erreichbare Zielgruppen, in Prävention und Gesundheitsförderung, 2019, Springer: Heidelberg.

731. Geber, S., Baumann, E., Klimmt, C., Tailoring in risk communication by linking risk profiles and communication preferences: The case of speeding of young car drivers, Accid Anal Prev, 2016. 97: p. 315-325., https://www.ncbi.nlm.nih.gov/pubmed/26432690

732. Roski, R, Akteure, Ziele und Stakeholder im Gesundheitswesen - Business Marketing, Social Marketing und Zielgruppensegmentierung, in Zielgruppengerechte Gesundheitskommunikation, Roski, R , Editor. 2009, Springer VS: Wiesbaden. p. 3-31.

733. Baumann, E, Auf der Suche nach der Zielgruppe - Das Informationsverhalten hinsichtlich Gesundheit und Krankheit als Grundlage erfolgreicher Gesundheitskommunikation, in Gesundheitsmonitor 2006. Gesundheitsversorgung und Gestaltungsoptionen aus der Perspektive von Bevölkerung und Ärzten, Böcken, JBraun, BAmhof, R and Schnee, M, Editors. 2006, Verlag Bertelsmann Stiftung: Gütersloh. p. 117-153.

734. Robinson, J. K., Stapleton, J., Turrisi, R., Relationship and partner moderator variables increase self-efficacy of performing skin self-examination, J Am Acad Dermatol, 2008. 58(5): p. 755-62., https://www.ncbi.nlm.nih.gov/pubmed/18258332

735. Geller, A. C., Emmons, K. M., Brooks, D. R., Powers, C., Zhang, Z., Koh, H. K., et.al. A randomized trial to improve early detection and prevention practices among siblings of melanoma patients, Cancer, 2006. 107(4): p. 806-14., https://www.ncbi.nlm.nih.gov/pubmed/16832795

736. Manne, S., Jacobsen, P. B., Ming, M. E., Winkel, G., Dessureault, S., Lessin, S. R., Tailored versus generic interventions for skin cancer risk reduction for family members of melanoma patients, Health Psychol, 2010. 29(6): p. 583-93., https://www.ncbi.nlm.nih.gov/pubmed/21090893

737. Mayer, J. A., Eckhardt, L., Stepanski, B. M., Sallis, J. F., Elder, J. P., Slymen, D. J., et.al. Promoting skin cancer prevention counseling by pharmacists, Am J Public Health, 1998. 88(7): p. 1096-9., https://www.ncbi.nlm.nih.gov/pubmed/9663162

738. Youl, P. H., Janda, M., Elwood, M., Lowe, J. B., Ring, I. T., Aitken, J. F., Who attends skin cancer clinics within a randomized melanoma screening program?, Cancer Detect Prev, 2006. 30(1): p. 44-51., https://www.ncbi.nlm.nih.gov/pubmed/16457967

739. King, A. J., Visual Exemplification and Skin Cancer: The Utility of Exemplars in Promoting Skin Self-Exams and Atypical Nevi Identification, J Health Commun, 2016. 21(7): p. 826-36., https://www.ncbi.nlm.nih.gov/pubmed/27337542

740. McWhirter, J. E., Hoffman-Goetz, L., Visual images for patient skin self-examination and melanoma detection: a systematic review of published studies, J Am Acad Dermatol, 2013. 69(1): p. 47-55., https://www.ncbi.nlm.nih.gov/pubmed/23474227

741. Edwards, A. G., Naik, G., Ahmed, H., Elwyn, G. J., Pickles, T., Hood, K., et.al. Personalised risk communication for informed decision making about taking screening tests, Cochrane Database Syst Rev, 2013. p. CD001865., https://www.ncbi.nlm.nih.gov/pubmed/23450534

742. Anders, M. P., Nolte, S., Waldmann, A., Capellaro, M., Volkmer, B., Greinert, R., et.al. The German SCREEN project--design and evaluation of the communication strategy, Eur J Public Health, 2015. 25(1): p. 150-5., https://www.ncbi.nlm.nih.gov/pubmed/24760725

743. Schnabel, P, Bödeker, M, GesundheitskommunikationBeltz Juventa, 2012.

744. Janis, Irving Lester, Mann, Leon, Decision making: A psychological analysis of conflict, choice and commitmentCassel & Collier Macmillian, 1977.

745. Mann, Leon, Use of a balance-sheet procedure to improve the quality of personal decision making: A field experiment with college applicants, Journal of Vocational Behavior, 1972. 2(3): p. 291-300.

746. Mullen, P D, Allen, J D, Glanz, K, Fernandez, M E, Bowen, D J, Pruitt, S L, et.al. Measures Used in Studies of Informed Decision Making About Cancer Screening: A Systematic Review, Annals of Behavioral Medicine, 2006. 32(3): p. 188-201., https://www.ncbi.nlm.nih.gov/pubmed/17107291

747. Eppstein, R. M., Street Jr., R., Patient-Centered Communication in Cancer Care: Promoting Healing and Reducing SufferingBethesda, 2007.

748. Bientzle, M., Fissler, T., Cress, U., Kimmerle, J., The impact of physicians' communication styles on evaluation of physicians and information processing: A randomized study with simulated video consultations on contraception with an intrauterine device, Health Expect, 2017. 20(5): p. 845-851., https://www.ncbi.nlm.nih.gov/pubmed/27860037

749. Eggly, S. S., Albrecht, T. L., Kelly, K., Prigerson, H. G., Sheldon, L. K., Studts, J., The role of the clinician in cancer clinical communication, J Health Commun, 2009. 14 Suppl 1(Suppl1): p. 66-75., https://www.ncbi.nlm.nih.gov/pubmed/19449270

750. Fox, S. A., Heritage, J., Stockdale, S. E., Asch, S. M., Duan, N., Reise, S. P., Cancer screening adherence: does physician-patient communication matter?, Patient Educ Couns, 2009. 75(2): p. 178-84., https://www.ncbi.nlm.nih.gov/pubmed/19250793

751. Riedl, D., Schussler, G., The Influence of Doctor-Patient Communication on Health Outcomes: A Systematic Review, Z Psychosom Med Psychother, 2017. 63(2): p. 131-150., https://www.ncbi.nlm.nih.gov/pubmed/28585507

752. Dillon, E. C., Stults, C. D., Wilson, C., Chuang, J., Meehan, A., Li, M., et.al. An evaluation of two interventions to enhance patient-physician communication using the observer OPTION(5) measure of shared decision making, Patient Educ Couns, 2017. 100(10): p. 1910-1917., https://www.ncbi.nlm.nih.gov/pubmed/28532861

753. Shay, L. A., Dumenci, L., Siminoff, L. A., Flocke, S. A., Lafata, J. E., Factors associated with patient reports of positive physician relational communication, Patient Educ Couns, 2012. 89(1): p. 96-101., https://www.ncbi.nlm.nih.gov/pubmed/22554386

754. Baker, Susan C., Watson, Bernadette M., How Patients Perceive Their Doctors’ Communication, Journal of Language and Social Psychology, 2015. 34(6): p. 621-639., http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc13a&AN=2015-51535-003, http://sfx.gbv.de/sfx_subhh?sid=OVID:psycdb&id=pmid:&id=doi:10.1177%2F0261927X15587015&issn=0261-927X&isbn=&volume=34&issue=6&spage=621&pages=621-639&date=2015&title=Journal+of+Language+and+Social+Psychology&atitle=How+patients+perceive+their+doctors%27+communication%3A+Implications+for+patient+willingness+to+communicate.&aulast=Baker

755. Thomas, Marlyn, Hariharan, Meena, Rana, Suvashisa, Swain, Sunayana, Andrew, Asher, Medical Jargons as Hindrance in Doctor–Patient Communication, Psychological Studies, 2014. 59(4): p. 394-400., http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc11&AN=2014-26202-001, http://sfx.gbv.de/sfx_subhh?sid=OVID:psycdb&id=pmid:&id=doi:10.1007%2Fs12646-014-0262-x&issn=0033-2968&isbn=&volume=59&issue=4&spage=394&pages=394-400&date=2014&title=Psychological+Studies&atitle=Medical+jargons+as+hindrance+in+doctor-patient+communication.&aulast=Thomas

756. Jünger, Jana, Ärtzliche Kommunikation: Praxisbuch zum Masterplan Medizinstudium 2020Schattauer, 2018.

757. Schweickhardt, A., Fritzsche, K., Kursbuch ärztliche Kommunikation: Grundlagen und Fallbeispiele aus Klinik und PraxisDeutscher Ärzte-Verlag, 2009.

758. Bundesministerium fuer Gesundheit, „Inanspruchnahme Krebsfrüherkennung“, Handlungsfeld 1 „Weiterentwicklung der Krebsfrüherkennung“ des Nationalen Krebsplans, 2010.

759. Loescher, L. J., Crist, J. D., Cranmer, L., Curiel-Lewandrowski, C., Warneke, J. A., Melanoma high-risk families' perceived health care provider risk communication, J Cancer Educ, 2009. 24(4): p. 301-7., https://www.ncbi.nlm.nih.gov/pubmed/19838889

760. Loescher, L. J., Crist, J. D., Siaki, L. A., Perceived intrafamily melanoma risk communication, Cancer Nurs, 2009. 32(3): p. 203-10., https://www.ncbi.nlm.nih.gov/pubmed/19295423

761. Graves, J., Fleischman, M. H., Goldstein, G. D., Derm Access: a new triage system to rapidly identify suspicious skin lesions, Dermatol Surg, 2006. 32(12): p. 1486-90., https://www.ncbi.nlm.nih.gov/pubmed/17199657

762. Karri, V., Bragg, T. W., Jones, A., Soldin, M., Misch, K., Patient satisfaction with receiving skin cancer diagnosis by letter: comparison with face-to-face consultation, J Plast Reconstr Aesthet Surg, 2009. 62(8): p. 1059-62., https://www.ncbi.nlm.nih.gov/pubmed/18485851

763. Bahmer, J., Bahmer, F., Konfrontation mit der Diagnose „Melanom”, Aktuelle Dermatologie, 2006. 32(6): p. 243-248.

764. Butow, P. N., Kazemi, J. N., Beeney, L. J., Griffin, A. M., Dunn, S. M., Tattersall, M. H., When the diagnosis is cancer: patient communication experiences and preferences, Cancer, 1996. 77(12): p. 2630-7., https://www.ncbi.nlm.nih.gov/pubmed/8640715

765. Baile, W. F., Buckman, R., Lenzi, R., Glober, G., Beale, E. A., Kudelka, A. P., SPIKES-A six-step protocol for delivering bad news: application to the patient with cancer, Oncologist, 2000. 5(4): p. 302-11., https://www.ncbi.nlm.nih.gov/pubmed/10964998

766. Bafounta, M. L., Beauchet, A., Aegerter, P., Saiag, P., Is dermoscopy (epiluminescence microscopy) useful for the diagnosis of melanoma? Results of a meta-analysis using techniques adapted to the evaluation of diagnostic tests, Arch Dermatol, 2001. 137(10): p. 1343-50., https://www.ncbi.nlm.nih.gov/pubmed/11594860

767. Kittler, H., Pehamberger, H., Wolff, K., Binder, M., Diagnostic accuracy of dermoscopy, Lancet Oncol, 2002. 3(3): p. 159-65., https://www.ncbi.nlm.nih.gov/pubmed/11902502

768. Dolianitis, C., Kelly, J., Wolfe, R., Simpson, P., Comparative performance of 4 dermoscopic algorithms by nonexperts for the diagnosis of melanocytic lesions, Arch Dermatol, 2005. 141(8): p. 1008-14., https://www.ncbi.nlm.nih.gov/pubmed/16103330

769. Westerhoff, K., McCarthy, W. H., Menzies, S. W., Increase in the sensitivity for melanoma diagnosis by primary care physicians using skin surface microscopy, Br J Dermatol, 2000. 143(5): p. 1016-20., https://www.ncbi.nlm.nih.gov/pubmed/11069512

770. Carli, P., de Giorgi, V., Chiarugi, A., Nardini, P., Weinstock, M. A., Crocetti, E., et.al. Addition of dermoscopy to conventional naked-eye examination in melanoma screening: a randomized study, J Am Acad Dermatol, 2004. 50(5): p. 683-9., https://www.ncbi.nlm.nih.gov/pubmed/15097950

771. van der Rhee, J. I., Bergman, W., Kukutsch, N. A., The impact of dermoscopy on the management of pigmented lesions in everyday clinical practice of general dermatologists: a prospective study, Br J Dermatol, 2010. 162(3): p. 563-7., https://www.ncbi.nlm.nih.gov/pubmed/19832836

772. Haenssle, H. A., Vente, C., Bertsch, H. P., Rupprecht, R., Abuzahra, F., Junghans, V., et.al. Results of a surveillance programme for patients at high risk of malignant melanoma using digital and conventional dermoscopy, Eur J Cancer Prev, 2004. 13(2): p. 133-8., https://www.ncbi.nlm.nih.gov/pubmed/15100580

773. Carli, P., De Giorgi, V., Argenziano, G., Palli, D., Giannotti, B., Pre-operative diagnosis of pigmented skin lesions: in vivo dermoscopy performs better than dermoscopy on photographic images, J Eur Acad Dermatol Venereol, 2002. 16(4): p. 339-46., https://www.ncbi.nlm.nih.gov/pubmed/12224689

774. Lorentzen, H. F., Eefsen, R. L., Weismann, K., Comparison of classical dermatoscopy and acrylic globe magnifier dermatoscopy, Acta Derm Venereol, 2008. 88(2): p. 139-42., https://www.ncbi.nlm.nih.gov/pubmed/18311441

775. Zalaudek, I., Kreusch, J., Giacomel, J., Ferrara, G., Catricala, C., Argenziano, G., How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part I. Melanocytic skin tumors, J Am Acad Dermatol, 2010. 63(3): p. 361-74; quiz 375-6., https://www.ncbi.nlm.nih.gov/pubmed/20708469

776. Australian Cancer Network Melanoma Guidelines Revision Working Party, Clinical Practice Guidelines for the Management of Melanoma in Australia and New ZealandThe Cancer Council Australia and Australian Cancer Network, Sydney and New Zealand Guidelines Group, 2008.

777. Carli, P., De Giorgi, V., Crocetti, E., Mannone, F., Massi, D., Chiarugi, A., et.al. Improvement of malignant/benign ratio in excised melanocytic lesions in the 'dermoscopy era': a retrospective study 1997-2001, Br J Dermatol, 2004. 150(4): p. 687-92., https://www.ncbi.nlm.nih.gov/pubmed/15099364

778. Drugge, R. J., Nguyen, C., Drugge, E. D., Gliga, L., Broderick, P. A., McClain, S. A., et.al. Melanoma screening with serial whole body photographic change detection using Melanoscan technology, Dermatol Online J, 2009. 15(6): p. 1., https://www.ncbi.nlm.nih.gov/pubmed/19723475

779. Malvehy, J., Puig, S., Follow-up of melanocytic skin lesions with digital total-body photography and digital dermoscopy: a two-step method, Clin Dermatol, 2002. 20(3): p. 297-304., https://www.ncbi.nlm.nih.gov/pubmed/12074871

780. English, D. R., Burton, R. C., del Mar, C. B., Donovan, R. J., Ireland, P. D., Emery, G., Evaluation of aid to diagnosis of pigmented skin lesions in general practice: controlled trial randomised by practice, BMJ, 2003. 327(7411): p. 375., https://www.ncbi.nlm.nih.gov/pubmed/12919990

781. Del Mar, C. B., Green, A. C., Aid to diagnosis of melanoma in primary medical care, BMJ, 1995. 310(6978): p. 492-5., https://www.ncbi.nlm.nih.gov/pubmed/7888887

782. Guitera, P., Menzies, S. W., Longo, C., Cesinaro, A. M., Scolyer, R. A., Pellacani, G., In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: analysis of 710 consecutive clinically equivocal cases, J Invest Dermatol, 2012. 132(10): p. 2386-2394., https://www.ncbi.nlm.nih.gov/pubmed/22718115

783. Manousaki, A. G., Manios, A. G., Tsompanaki, E. I., Panayiotides, J. G., Tsiftsis, D. D., Kostaki, A. K., et.al. A simple digital image processing system to aid in melanoma diagnosis in an everyday melanocytic skin lesion unit: a preliminary report, Int J Dermatol, 2006. 45(4): p. 402-10., https://www.ncbi.nlm.nih.gov/pubmed/16650167

784. Haenssle, H. A., Krueger, U., Vente, C., Thoms, K. M., Bertsch, H. P., Zutt, M., et.al. Results from an observational trial: digital epiluminescence microscopy follow-up of atypical nevi increases the sensitivity and the chance of success of conventional dermoscopy in detecting melanoma, J Invest Dermatol, 2006. 126(5): p. 980-5., https://www.ncbi.nlm.nih.gov/pubmed/16514414

785. Haenssle, H. A., Mograby, N., Ngassa, A., Buhl, T., Emmert, S., Schon, M. P., et.al. Association of Patient Risk Factors and Frequency of Nevus-Associated Cutaneous Melanomas, JAMA Dermatol, 2016. 152(3): p. 291-8., https://www.ncbi.nlm.nih.gov/pubmed/26536613

786. Kittler, H., Guitera, P., Riedl, E., Avramidis, M., Teban, L., Fiebiger, M., et.al. Identification of clinically featureless incipient melanoma using sequential dermoscopy imaging, Arch Dermatol, 2006. 142(9): p. 1113-9., https://www.ncbi.nlm.nih.gov/pubmed/16982998

787. Menzies, S. W., A method for the diagnosis of primary cutaneous melanoma using surface microscopy, Dermatol Clin, 2001. 19(2): p. 299-305, viii., https://www.ncbi.nlm.nih.gov/pubmed/11556238

788. Robinson, J. K., Nickoloff, B. J., Digital epiluminescence microscopy monitoring of high-risk patients, Arch Dermatol, 2004. 140(1): p. 49-56., https://www.ncbi.nlm.nih.gov/pubmed/14732660

789. Menzies, S. W., Gutenev, A., Avramidis, M., Batrac, A., McCarthy, W. H., Short-term digital surface microscopic monitoring of atypical or changing melanocytic lesions, Arch Dermatol, 2001. 137(12): p. 1583-9., https://www.ncbi.nlm.nih.gov/pubmed/11735708

790. Leitlinienprogramm Onkologie, S3 Leitlinie Diagnostik, Therapie und Nachsorge des Melanoms, 2019., https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Melanom/Melanom_Version_3/LL_Melanom_Langversion_3.1.pdf

791. Menzies, S. W., Emery, J., Staples, M., Davies, S., McAvoy, B., Fletcher, J., et.al. Impact of dermoscopy and short-term sequential digital dermoscopy imaging for the management of pigmented lesions in primary care: a sequential intervention trial, Br J Dermatol, 2009. 161(6): p. 1270-7., https://www.ncbi.nlm.nih.gov/pubmed/19747359

792. Ferrandiz, L., Moreno-Ramirez, D., Nieto-Garcia, A., Carrasco, R., Moreno-Alvarez, P., Galdeano, R., et.al. Teledermatology-based presurgical management for nonmelanoma skin cancer: a pilot study, Dermatol Surg, 2007. 33(9): p. 1092-8., https://www.ncbi.nlm.nih.gov/pubmed/17760600

793. Moreno-Ramirez, D., Ferrandiz, L., Nieto-Garcia, A., Carrasco, R., Moreno-Alvarez, P., Galdeano, R., et.al. Store-and-forward teledermatology in skin cancer triage: experience and evaluation of 2009 teleconsultations, Arch Dermatol, 2007. 143(4): p. 479-84., https://www.ncbi.nlm.nih.gov/pubmed/17438180

794. May, C., Giles, L., Gupta, G., Prospective observational comparative study assessing the role of store and forward teledermatology triage in skin cancer, Clin Exp Dermatol, 2008. 33(6): p. 736-9., https://www.ncbi.nlm.nih.gov/pubmed/18681874

795. Jolliffe, V. M., Harris, D. W., Whittaker, S. J., Can we safely diagnose pigmented lesions from stored video images? A diagnostic comparison between clinical examination and stored video images of pigmented lesions removed for histology, Clin Exp Dermatol, 2001. 26(1): p. 84-7., https://www.ncbi.nlm.nih.gov/pubmed/11260186

796. Warshaw, E. M., Lederle, F. A., Grill, J. P., Gravely, A. A., Bangerter, A. K., Fortier, L. A., et.al. Accuracy of teledermatology for pigmented neoplasms, J Am Acad Dermatol, 2009. 61(5): p. 753-65., https://www.ncbi.nlm.nih.gov/pubmed/19679375

797. Kittler, H., Seltenheim, M., Pehamberger, H., Wolff, K., Binder, M., Diagnostic informativeness of compressed digital epiluminescence microscopy images of pigmented skin lesions compared with photographs, Melanoma Res, 1998. 8(3): p. 255-60., https://www.ncbi.nlm.nih.gov/pubmed/9664147

798. Bono, Aldo, Bartoli, Cesare, Cascinelli, Natale, Lualdi, Manuela, Maurichi, Andrea, Moglia, Daniele, et.al. Melanoma detection - A prospective study comparing diagnosis with the naked eye, dermatoscopy and telespectrophotometry, Dermatology, 2002. 205(4): p. 362-366.

799. Bono, A., Tomatis, S., Bartoli, C., Tragni, G., Radaelli, G., Maurichi, A., et.al. The ABCD system of melanoma detection: a spectrophotometric analysis of the Asymmetry, Border, Color, and Dimension, Cancer, 1999. 85(1): p. 72-7., https://www.ncbi.nlm.nih.gov/pubmed/9921976

800. Haniffa, M. A., Lloyd, J. J., Lawrence, C. M., The use of a spectrophotometric intracutaneous analysis device in the real-time diagnosis of melanoma in the setting of a melanoma screening clinic, Br J Dermatol, 2007. 156(6): p. 1350-2., https://www.ncbi.nlm.nih.gov/pubmed/17535234

801. McIntosh, L. M., Summers, R., Jackson, M., Mantsch, H. H., Mansfield, J. R., Howlett, M., et.al. Towards non-invasive screening of skin lesions by near-infrared spectroscopy, J Invest Dermatol, 2001. 116(1): p. 175-81., https://www.ncbi.nlm.nih.gov/pubmed/11168814

802. S1-Leitlinie Konfokale Lasermikroskopie in der Dermatologie, 2019.

803. Kadouch, D. J., Schram, M. E., Leeflang, M. M., Limpens, J., Spuls, P. I., de Rie, M. A., In vivo confocal microscopy of basal cell carcinoma: a systematic review of diagnostic accuracy, J Eur Acad Dermatol Venereol, 2015. 29(10): p. 1890-7., https://www.ncbi.nlm.nih.gov/pubmed/26290493

804. Edwards, S. J., Osei-Assibey, G., Patalay, R., Wakefield, V., Karner, C., Diagnostic accuracy of reflectance confocal microscopy using VivaScope for detecting and monitoring skin lesions: a systematic review, Clin Exp Dermatol, 2017. 42(3): p. 266-275., https://www.ncbi.nlm.nih.gov/pubmed/28218469

805. Couzan, C., Cinotti, E., Labeille, B., Vercherin, P., Rubegni, P., Cambazard, F., et.al. Reflectance confocal microscopy identification of subclinical basal cell carcinomas during and after vismodegib treatment, J Eur Acad Dermatol Venereol, 2018. 32(5): p. 763-767., https://www.ncbi.nlm.nih.gov/pubmed/29055164

806. Guitera, P., Pellacani, G., Longo, C., Seidenari, S., Avramidis, M., Menzies, S. W., In vivo reflectance confocal microscopy enhances secondary evaluation of melanocytic lesions, J Invest Dermatol, 2009. 129(1): p. 131-8., https://www.ncbi.nlm.nih.gov/pubmed/18633444

807. Lorber, A., Wiltgen, M., Hofmann-Wellenhof, R., Koller, S., Weger, W., Ahlgrimm-Siess, V., et.al. Correlation of image analysis features and visual morphology in melanocytic skin tumours using in vivo confocal laser scanning microscopy, Skin Res Technol, 2009. 15(2): p. 237-41., https://www.ncbi.nlm.nih.gov/pubmed/19622133

808. Stevenson, A. D., Mickan, S., Mallett, S., Ayya, M., Systematic review of diagnostic accuracy of reflectance confocal microscopy for melanoma diagnosis in patients with clinically equivocal skin lesions, Dermatol Pract Concept, 2013. 3(4): p. 19-27., https://www.ncbi.nlm.nih.gov/pubmed/24282659

809. Xiong, Y. D., Ma, S., Li, X., Zhong, X., Duan, C., Chen, Q., A meta-analysis of reflectance confocal microscopy for the diagnosis of malignant skin tumours, J Eur Acad Dermatol Venereol, 2016. 30(8): p. 1295-302., https://www.ncbi.nlm.nih.gov/pubmed/27230832

810. Alarcon, I., Carrera, C., Palou, J., Alos, L., Malvehy, J., Puig, S., Impact of in vivo reflectance confocal microscopy on the number needed to treat melanoma in doubtful lesions, Br J Dermatol, 2014. 170(4): p. 802-8., https://www.ncbi.nlm.nih.gov/pubmed/24124911

811. Pellacani, G., Pepe, P., Casari, A., Longo, C., Reflectance confocal microscopy as a second-level examination in skin oncology improves diagnostic accuracy and saves unnecessary excisions: a longitudinal prospective study, Br J Dermatol, 2014. 171(5): p. 1044-51., https://www.ncbi.nlm.nih.gov/pubmed/24891083

812. Pellacani, G., Witkowski, A., Cesinaro, A. M., Losi, A., Colombo, G. L., Campagna, A., et.al. Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma, J Eur Acad Dermatol Venereol, 2016. 30(3): p. 413-9., https://www.ncbi.nlm.nih.gov/pubmed/26446299

813. Seidenari, S., Arginelli, F., Dunsby, C., French, P. M., Konig, K., Magnoni, C., et.al. Multiphoton laser tomography and fluorescence lifetime imaging of melanoma: morphologic features and quantitative data for sensitive and specific non-invasive diagnostics, PLoS One, 2013. 8(7): p. e70682., https://www.ncbi.nlm.nih.gov/pubmed/23923016

814. Balu, M., Kelly, K. M., Zachary, C. B., Harris, R. M., Krasieva, T. B., Konig, K., et.al. Distinguishing between benign and malignant melanocytic nevi by in vivo multiphoton microscopy, Cancer Res, 2014. 74(10): p. 2688-97., https://www.ncbi.nlm.nih.gov/pubmed/24686168

815. Cheng, H. M., Guitera, P., Systematic review of optical coherence tomography usage in the diagnosis and management of basal cell carcinoma, Br J Dermatol, 2015. 173(6): p. 1371-80., https://www.ncbi.nlm.nih.gov/pubmed/26211438

816. Cheng, H. M., Lo, S., Scolyer, R., Meekings, A., Carlos, G., Guitera, P., Accuracy of optical coherence tomography for the diagnosis of superficial basal cell carcinoma: a prospective, consecutive, cohort study of 168 cases, Br J Dermatol, 2016. 175(6): p. 1290-1300., https://www.ncbi.nlm.nih.gov/pubmed/27146027

817. Coleman, A. J., Richardson, T. J., Orchard, G., Uddin, A., Choi, M. J., Lacy, K. E., Histological correlates of optical coherence tomography in non-melanoma skin cancer, Skin Res Technol, 2013. 19(1): p. 10-9., https://www.ncbi.nlm.nih.gov/pubmed/22738357

818. Hussain, A. A., Themstrup, L., Jemec, G. B., Optical coherence tomography in the diagnosis of basal cell carcinoma, Arch Dermatol Res, 2015. 307(1): p. 1-10., https://www.ncbi.nlm.nih.gov/pubmed/25223745

819. Markowitz, O., Schwartz, M., Feldman, E., Bienenfeld, A., Bieber, A. K., Ellis, J., et.al. Evaluation of Optical Coherence Tomography as a Means of Identifying Earlier Stage Basal Cell Carcinomas while Reducing the Use of Diagnostic Biopsy, J Clin Aesthet Dermatol, 2015. 8(10): p. 14-20., https://www.ncbi.nlm.nih.gov/pubmed/26557214

820. Olsen, J., Themstrup, L., De Carvalho, N., Mogensen, M., Pellacani, G., Jemec, G. B., Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma, Photodiagnosis Photodyn Ther, 2016. 16: p. 44-49., https://www.ncbi.nlm.nih.gov/pubmed/27519350

821. Ulrich, M., von Braunmuehl, T., Kurzen, H., Dirschka, T., Kellner, C., Sattler, E., et.al. The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study, Br J Dermatol, 2015. 173(2): p. 428-35., https://www.ncbi.nlm.nih.gov/pubmed/25904111

822. Gambichler, T., Schmid-Wendtner, M. H., Plura, I., Kampilafkos, P., Stucker, M., Berking, C., et.al. A multicentre pilot study investigating high-definition optical coherence tomography in the differentiation of cutaneous melanoma and melanocytic naevi, J Eur Acad Dermatol Venereol, 2015. 29(3): p. 537-41., https://www.ncbi.nlm.nih.gov/pubmed/25073788

823. Malvehy, J., Hauschild, A., Curiel-Lewandrowski, C., Mohr, P., Hofmann-Wellenhof, R., Motley, R., et.al. Clinical performance of the Nevisense system in cutaneous melanoma detection: an international, multicentre, prospective and blinded clinical trial on efficacy and safety, Br J Dermatol, 2014. 171(5): p. 1099-107., https://www.ncbi.nlm.nih.gov/pubmed/24841846

824. Lassau, N., Spatz, A., Avril, M. F., Tardivon, A., Margulis, A., Mamelle, G., et.al. Value of high-frequency US for preoperative assessment of skin tumors, Radiographics, 1997. 17(6): p. 1559-65., https://www.ncbi.nlm.nih.gov/pubmed/9397463

825. Krahn, G., Gottlober, P., Sander, C., Peter, R. U., Dermatoscopy and high frequency sonography: two useful non-invasive methods to increase preoperative diagnostic accuracy in pigmented skin lesions, Pigment Cell Res, 1998. 11(3): p. 151-4., https://www.ncbi.nlm.nih.gov/pubmed/9730322

826. Wortsman, X., Wortsman, J., Clinical usefulness of variable-frequency ultrasound in localized lesions of the skin, J Am Acad Dermatol, 2010. 62(2): p. 247-56., https://www.ncbi.nlm.nih.gov/pubmed/19962214

827. Elbaum, M., Kopf, A. W., Rabinovitz, H. S., Langley, R. G., Kamino, H., Mihm, M. C., Jr., et.al. Automatic differentiation of melanoma from melanocytic nevi with multispectral digital dermoscopy: a feasibility study, J Am Acad Dermatol, 2001. 44(2): p. 207-18., https://www.ncbi.nlm.nih.gov/pubmed/11174377

828. Monheit, G., Cognetta, A. B., Ferris, L., Rabinovitz, H., Gross, K., Martini, M., et.al. The performance of MelaFind: a prospective multicenter study, Arch Dermatol, 2011. 147(2): p. 188-94., https://www.ncbi.nlm.nih.gov/pubmed/20956633

829. Hauschild, A., Chen, S. C., Weichenthal, M., Blum, A., King, H. C., Goldsmith, J., et.al. To excise or not: impact of MelaFind on German dermatologists' decisions to biopsy atypical lesions, J Dtsch Dermatol Ges, 2014. 12(7): p. 606-14., https://www.ncbi.nlm.nih.gov/pubmed/24944011

830. Lim, L., Nichols, B., Migden, M. R., Rajaram, N., Reichenberg, J. S., Markey, M. K., et.al. Clinical study of noninvasive in vivo melanoma and nonmelanoma skin cancers using multimodal spectral diagnosis, J Biomed Opt, 2014. 19(11): p. 117003., https://www.ncbi.nlm.nih.gov/pubmed/25375350

831. Philipsen, P. A., Knudsen, L., Gniadecka, M., Ravnbak, M. H., Wulf, H. C., Diagnosis of malignant melanoma and basal cell carcinoma by in vivo NIR-FT Raman spectroscopy is independent of skin pigmentation, Photochem Photobiol Sci, 2013. 12(5): p. 770-6., https://www.ncbi.nlm.nih.gov/pubmed/23348560

832. Kassenärztliche Bundesvereinigung, Bekanntmachungen Vereinbarung von Qualitätssicherungsmaßnahmen nach § 135 Abs. 2 SGB V zur histopathologischen Untersuchung im Rahmen des Hautkrebs-Screenings (Qualitätssicherungsvereinbarung Histopathologie Hautkrebs-Screening), Dtsch Arztebl, 2009. 106(39): p. A-1924 / B-1652 / C-1620.

833. Manstein, M. E., Manstein, C. H., Smith, R., How accurate is frozen section for skin cancers?, Ann Plast Surg, 2003. 50(6): p. 607-9., https://www.ncbi.nlm.nih.gov/pubmed/12783011

834. Tran, Kien T., Wright, Natalie A., Cockerell, Clay J., Biopsy of the pigmented lesion—When and how, Journal of the American Academy of Dermatology, 2008. 59(5): p. 852-871., http://linkinghub.elsevier.com/retrieve/pii/S0190962208006579?showall=true

835. Martin, R. C., 2nd, Scoggins, C. R., Ross, M. I., Reintgen, D. S., Noyes, R. D., Edwards, M. J., et.al. Is incisional biopsy of melanoma harmful?, Am J Surg, 2005. 190(6): p. 913-7., https://www.ncbi.nlm.nih.gov/pubmed/16307945

836. Zager, J. S., Hochwald, S. N., Marzban, S. S., Francois, R., Law, K. M., Davis, A. H., et.al. Shave biopsy is a safe and accurate method for the initial evaluation of melanoma, J Am Coll Surg, 2011. 212(4): p. 454-60; discussion 460-2., https://www.ncbi.nlm.nih.gov/pubmed/21463767

837. Kassenärztliche, Bundesvereinigung, IT in der Arztpraxis: Anforderungskatalog Hautkrebs-Screening (eHKS), 2012.

838. Messina, M. C. D. L., Valente, N. Y. S., Castroe, L. G. M., Is incisional biopsy helpful in the histopathological classification of basal cell carcinoma?, Anais Brasileiros de Dermatologia, 2006. p. 81(5)(pp 443-448), 2006.

839. Fawzy, N. W., A psychoeducational nursing intervention to enhance coping and affective state in newly diagnosed malignant melanoma patients, Cancer Nurs, 1995. 18(6): p. 427-38., https://www.ncbi.nlm.nih.gov/pubmed/8564938

840. Trask, P. C., Paterson, A. G., Griffith, K. A., Riba, M. B., Schwartz, J. L., Cognitive-behavioral intervention for distress in patients with melanoma: comparison with standard medical care and impact on quality of life, Cancer, 2003. 98(4): p. 854-64., https://www.ncbi.nlm.nih.gov/pubmed/12910531

841. Loquai, C., Schmidtmann, I., Beutel, M., Sunderkotter, C., Grabbe, S., Schiller, M., et.al. Quality of life in melanoma patients during adjuvant treatment with pegylated interferon-alpha2b: patients' and doctors' views, Eur J Dermatol, 2011. 21(6): p. 976-84., https://www.ncbi.nlm.nih.gov/pubmed/21896421

842. Dunn, J., Watson, M., Aitken, J. F., Hyde, M. K., Systematic review of psychosocial outcomes for patients with advanced melanoma, Psychooncology, 2017. 26(11): p. 1722-1731., https://www.ncbi.nlm.nih.gov/pubmed/27696578

843. Gjorup, C. A., Groenvold, M., Hendel, H. W., Dahlstroem, K., Drzewiecki, K. T., Klausen, T. W., et.al. Health-related quality of life in melanoma patients: Impact of melanoma-related limb lymphoedema, Eur J Cancer, 2017. 85: p. 122-132., https://www.ncbi.nlm.nih.gov/pubmed/28918186

844. Waalboer-Spuij, R., Nijsten, T. E., A review on quality of life in keratinocyte carcinoma patients, G Ital Dermatol Venereol, 2013. 148(3): p. 249-54., https://www.ncbi.nlm.nih.gov/pubmed/23670061

845. Tennvall, G. R., Norlin, J. M., Malmberg, I., Erlendsson, A. M., Haedersdal, M., Health related quality of life in patients with actinic keratosis--an observational study of patients treated in dermatology specialist care in Denmark, Health Qual Life Outcomes, 2015. 13: p. 111., https://www.ncbi.nlm.nih.gov/pubmed/26220553

846. Guy, G. P., Jr., Zhang, Y., Ekwueme, D. U., Rim, S. H., Watson, M., The potential impact of reducing indoor tanning on melanoma prevention and treatment costs in the United States: An economic analysis, J Am Acad Dermatol, 2017. 76(2): p. 226-233., https://www.ncbi.nlm.nih.gov/pubmed/27939556

847. Hirst, N., Gordon, L., Gies, P., Green, A. C., Estimation of avoidable skin cancers and cost-savings to government associated with regulation of the solarium industry in Australia, Health Policy, 2009. 89(3): p. 303-11., https://www.ncbi.nlm.nih.gov/pubmed/18760857

848. Waters, Hugh R., Adamson, Adewole, The health and economic implications of the use of tanning devices, Journal of Cancer Policy, 2018. 17: p. 45-50., http://www.sciencedirect.com/science/article/pii/S2213538316300340

849. Pil, L., Hoorens, I., Vossaert, K., Kruse, V., Tromme, I., Speybroeck, N., et.al. Burden of skin cancer in Belgium and cost-effectiveness of primary prevention by reducing ultraviolet exposure, Prev Med, 2016. 93: p. 177-182., https://www.ncbi.nlm.nih.gov/pubmed/27713103

850. Kyle, J. W., Hammitt, J. K., Lim, H. W., Geller, A. C., Hall-Jordan, L. H., Maibach, E. W., et.al. Economic evaluation of the US Environmental Protection Agency's SunWise program: sun protection education for young children, Pediatrics, 2008. 121(5): p. e1074-84., https://www.ncbi.nlm.nih.gov/pubmed/18450850

851. Shih, S. T., Carter, R., Sinclair, C., Mihalopoulos, C., Vos, T., Economic evaluation of skin cancer prevention in Australia, Prev Med, 2009. 49(5): p. 449-53., https://www.ncbi.nlm.nih.gov/pubmed/19747936

852. Shih, S. T., Carter, R., Heward, S., Sinclair, C., Economic evaluation of future skin cancer prevention in Australia, Prev Med, 2017. 99: p. 7-12., https://www.ncbi.nlm.nih.gov/pubmed/28131778

853. Gordon, L. G., Rowell, D., Health system costs of skin cancer and cost-effectiveness of skin cancer prevention and screening: a systematic review, Eur J Cancer Prev, 2015. 24(2): p. 141-9., https://www.ncbi.nlm.nih.gov/pubmed/25089375

854. Gordon, L. G., Brynes, J., Baade, P. D., Neale, R. E., Whiteman, D. C., Youl, P. H., et.al. Cost-Effectiveness Analysis of a Skin Awareness Intervention for Early Detection of Skin Cancer Targeting Men Older Than 50 Years, Value Health, 2017. 20(4): p. 593-601., https://www.ncbi.nlm.nih.gov/pubmed/28408001

855. Hirst, N. G., Gordon, L. G., Scuffham, P. A., Green, A. C., Lifetime cost-effectiveness of skin cancer prevention through promotion of daily sunscreen use, Value Health, 2012. 15(2): p. 261-8., https://www.ncbi.nlm.nih.gov/pubmed/22433757

856. Anderson, A. J. M., Ferris, L. K., Binion, D. G., Smith, K. J., Cost-Effectiveness of Melanoma Screening in Inflammatory Bowel Disease, Dig Dis Sci, 2018. 63(10): p. 2564-2572., https://www.ncbi.nlm.nih.gov/pubmed/29948569

857. Wilson, E. C. F., Usher-Smith, J. A., Emery, J., Corrie, P., Walter, F. M., A Modeling Study of the Cost-Effectiveness of a Risk-Stratified Surveillance Program for Melanoma in the United Kingdom, Value Health, 2018. 21(6): p. 658-668., https://www.ncbi.nlm.nih.gov/pubmed/29909870

858. Watts, C. G., Cust, A. E., Menzies, S. W., Mann, G. J., Morton, R. L., Cost-Effectiveness of Skin Surveillance Through a Specialized Clinic for Patients at High Risk of Melanoma, J Clin Oncol, 2017. 35(1): p. 63-71., https://www.ncbi.nlm.nih.gov/pubmed/28034073

859. Okafor, P. N., Stallwood, C. G., Nguyen, L., Sahni, D., Wasan, S. K., Farraye, F. A., et.al. Cost-effectiveness of nonmelanoma skin cancer screening in Crohn's disease patients, Inflamm Bowel Dis, 2013. 19(13): p. 2787-95., https://www.ncbi.nlm.nih.gov/pubmed/24193153

860. Losina, E., Walensky, R. P., Geller, A., Beddingfield, F. C., 3rd, Wolf, L. L., Gilchrest, B. A., et.al. Visual screening for malignant melanoma: a cost-effectiveness analysis, Arch Dermatol, 2007. 143(1): p. 21-8., https://www.ncbi.nlm.nih.gov/pubmed/17224538

861. Beddingfield, Iii, Melanoma: A Decision Analysis to Estimate the Effectiveness and Cost-Effectiveness of Screening and an Analysis of the Relevant Epidemiology of the Disease, 2002.

862. Freedberg, K. A., Geller, A. C., Miller, D. R., Lew, R. A., Koh, H. K., Screening for malignant melanoma: A cost-effectiveness analysis, J Am Acad Dermatol, 1999. 41(5 Pt 1): p. 738-45., https://www.ncbi.nlm.nih.gov/pubmed/10534637

863. Girgis, A., Clarke, P., Burton, R. C., Sanson-Fisher, R. W., Screening for melanoma by primary health care physicians: a cost-effectiveness analysis, J Med Screen, 1996. 3(1): p. 47-53., https://www.ncbi.nlm.nih.gov/pubmed/8861052

864. Siebert, U., When should decision-analytic modeling be used in the economic evaluation of health care? [Editorial], European Journal of Health Economics, 2003. 4(3): p. 143-150., pdf, C:\!Fulltext\Siebert\Siebert_2003_Eur, J, Health, Econom_When, should, DA, modeling, be, used, in, econom, eval.pdf

865. Siebert, U., Transparente Entscheidungen in Public Health mittels systematischer Entscheidungsanalyse, in Public Health. Gesundheit und Gesundheitswesen, Schwartz, F. W.Walter, U.Siegrist, J.Kolip, P.Leidl, R.Dierks, M.-L.Busse, R. and Schneider, N., Editors. 2012, Urban & Fischer in Elsevier: München. p. 517-535., pdf

866. Siebert, U., Alagoz, O., Bayoumi, A.M., Jahn, B., Owens, D.K., Cohen, D.J., et.al. State-Transition Modeling: A Report of the ISPOR-SMDM Modeling Good Research Practices Task Force -3, Medical Decision Making, 2012. 32(5): p. 690-700., pdf

867. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF), Erarbeitung von Leitlinien für Diagnostik und Therapie - Methodische Empfehlungen ("Leitlinie für Leitlinien", Stand Dez. 2004).Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF), 2004.

868. Lorenz, W., Ollenschläger, G., Geraedts, M., Gerlach, F., Gandjour, A., Helou, A., et.al. Das Leitlinien-Manual: Entwicklung und Implementierung von Leitlinien in der Medizin, Zeitschrift für ärztliche Fortbildung und Qualitätssicherung, 2001. 95(Suppl I): p. 1-84.

869. IQWiG, Allgemeine Methoden (Version 4.2)Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG), 2015.

870. Leidl, R., von der Schulenburg, J.M., Wasem, J., Ansätze und Methoden der ökonomischen Evaluation - eine internationale Perspektive Health Technology AssessmentNomos, 1999.